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Protein Overview: EG11540

General Information:
Name(s) found: wrbA / EG11540 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • NAD(P)H:quinone oxidoreductase / NAD(P)H:quinone oxidoreductase, type IV NQO; may protect against oxidative stress; dimeric, binds one FMN per monomer [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 198 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    membrane [IDALink to PubMed article]
    Biological Process: response to oxidative stress [IEPLink to PubMed article]
    negative regulation of transcription [IEA]
    Molecular Function: FMN binding [IDALink to PubMed article][IEA]
    oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVLVLYYS MYGHIETMAR AVAEGASKVD GAEVVVKRVP ETMPPQLFEK AGGKTQTAPV  60
   61 ATPQELADYD AIIFGTPTRF GNMSGQMRTF LDQTGGLWAS GALYGKLASV FSSTGTGGGQ 120
  121 EQTITSTWTT LAHHGMVIVP IGYAAQELFD VSQVRGGTPY GATTIAGGDG SRQPSQEELS 180
  181 IARYQGEYVA GLAVKLNG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] PSI-BLAST 39.39794 Structure of WrbA from Pseudomonas aeruginosa

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.32880196921974 bayes_pls_golite062009
  • binding
    		•  1.54529414520518 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.2698167260481 bayes_pls_golite062009
  • catalytic activity
    		•  0.275631658558537 bayes_pls_golite062009
  • protein binding
    		•  0.191220795572558 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0852528568191628 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle