| Protein: | GDH2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1092 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GDH2.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [25..1087] | [44..1025] |
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0.0 | [1..1092] | [1..1092] |
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0.0 | [24..1086] | [23..1029] |
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0.0 | [29..1081] | [92..1096] |
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0.0 | [231..1082] | [161..982] |
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0.0 | [405..1087] | [1..670] |
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0.0 | [40..660] | [34..677] |
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0.0 | [352..1068] | [548..1303] |
|
Region A: Residues: [1-377] |
1 11 21 31 41 51
| | | | | |
1 MLFDNKNRGA LNSLNTPDIA SLSISSMSDY HVFDFPGKDL QREEVIDLLD QQGFIPDDLI 60
61 EQEVDWFYNS LGIDDLFFSR ESPQLISNII HSLYASKLDF FAKSKFNGIQ PRLFSIKNKI 120
121 ITNDNHAIFM ESNTGVSISD SQQKNFKFAS DAVGNDTLEH GKDTIKKNRI EMDDSCPPYE 180
181 LDSEIDDLFL DNKSQKNCRL VSFWAPESEL KLTFVYESVY PNDDPAGVDI SSQDLLKGDI 240
241 ESISDKTMYK VSSNENKKLY GLLLKLVKER EGPVIKTTRS VENKDEIRLL VAYKRFTTKR 300
301 YYSALNSLFH YYKLKPSKFY LESFNVKDDD IIIFSVYLNE NQQLEDVLLH DVEAALKQVE 360
361 REASLLYAIP NNSFHEV
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [378-471] |
1 11 21 31 41 51
| | | | | |
1 YQRRQFSPKE AIYAHIGAIF INHFVNRLGS DYQNLLSQIT IKRNDTTLLE IVENLKRKLR 60
61 NETLTQQTII NIMSKHYTII SKLYKNFAQI HYYH
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.564 | a.4.1 | Homeodomain-like |
| View | Download | 0.565 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.495 | a.77.1 | DEATH domain |
| View | Download | 0.488 | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.452 | a.77.1 | DEATH domain |
| View | Download | 0.410 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.382 | a.39.1 | EF-hand |
| View | Download | 0.344 | a.77.1 | DEATH domain |
| View | Download | 0.329 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.318 | a.3.1 | Cytochrome c |
| View | Download | 0.318 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.309 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.306 | a.4.1 | Homeodomain-like |
| View | Download | 0.300 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.285 | a.3.1 | Cytochrome c |
| View | Download | 0.285 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.280 | a.74.1 | Cyclin-like |
| View | Download | 0.276 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.266 | c.47.1 | Thioredoxin-like |
| View | Download | 0.253 | d.93.1 | SH2 domain |
| View | Download | 0.249 | a.116.1 | GTPase activation domain, GAP |
| View | Download | 0.244 | d.164.1 | SMAD MH1 domain |
| View | Download | 0.240 | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.226 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.223 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.221 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.218 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.214 | c.47.1 | Thioredoxin-like |
| View | Download | 0.213 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.206 | a.68.1 | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain |
| View | Download | 0.201 | a.4.12 | TrpR-like |
|
Region A: Residues: [472-719] |
1 11 21 31 41 51
| | | | | |
1 NSTKDMEKTL SFQRLEKVEP FKNDQEFEAY LNKFIPNDSP DLLILKTLNI FNKSILKTNF 60
61 FITRKVAISF RLDPSLVMTK FEYPETPYGI FFVVGNTFKG FHIRFRDIAR GGIRIVCSRN 120
121 QDIYDLNSKN VIDENYQLAS TQQRKNKDIP EGGSKGVILL NPGLVEHDQT FVAFSQYVDA 180
181 MIDILINDPL KENYVNLLPK EEILFFGPDE GTAGFVDWAT NHARVRNCPW WKSFLTGKSP 240
241 SLGGIPHD
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|
Region B: Residues: [921-940] |
1 11 21 31 41 51
| | | | | |
1 GVTSSSMEVL ASLALNDNDF
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Region C: Residues: [971-1015] |
1 11 21 31 41 51
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1 AELEFGQLWN LNQLNGTHIS EISNQLSFTI NKLNDDLVAS QELWL
|
| Detection Method: | |
| Confidence: | 117.0 |
| Match: | 1euzA_ |
| Description: | Glutamate dehydrogenase |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [720-920] |
1 11 21 31 41 51
| | | | | |
1 EYGMTSLGVR AYVNKIYETL NLTNSTVYKF QTGGPDGDLG SNEILLSSPN ECYLAILDGS 60
61 GVLCDPKGLD KDELCRLAHE RKMISDFDTS KLSNNGFFVS VDAMDIMLPN GTIVANGTTF 120
121 RNTFHTQIFK FVDHVDIFVP CGGRPNSITL NNLHYFVDEK TGKCKIPYIV EGANLFITQP 180
181 AKNALEEHGC ILFKDASANK G
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|
Region B: Residues: [941-970] |
1 11 21 31 41 51
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1 VHKFIGDVSG ERSALYKSYV VEVQSRIQKN
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| Detection Method: | |
| Confidence: | 117.0 |
| Match: | 1euzA_ |
| Description: | Glutamate dehydrogenase |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | 4.08697502437308 | bayes_pls_golite062009 |
| oxidoreductase activity | 3.54983447672782 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on CH-OH group of donors | 2.66605122152932 | bayes_pls_golite062009 |
| malate dehydrogenase activity | 2.43636049081724 | bayes_pls_golite062009 |
| glutamate dehydrogenase (NADP+) activity | 2.29316799437014 | bayes_pls_golite062009 |
| catalytic activity | 2.0643953589843 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 1.54527841865655 | bayes_pls_golite062009 |
| malic enzyme activity | 1.39067036188188 | bayes_pls_golite062009 |
| glutamate dehydrogenase [NAD(P)+] activity | 0.994926158034199 | bayes_pls_golite062009 |
|
Region A: Residues: [1016-1092] |
1 11 21 31 41 51
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1 NDLKLRNYLL LDKIIPKILI DVAGPQSVLE NIPESYLKVL LSSYLSSTFV YQNGIDVNIG 60
61 KFLEFIGGLK REAEASA
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.538 | a.3.1 | Cytochrome c |
| View | Download | 0.638 | a.64.1 | Saposin |
| View | Download | 0.621 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.480 | a.68.1 | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain |
| View | Download | 0.465 | a.3.1 | Cytochrome c |
| View | Download | 0.424 | f.28.1 | Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.418 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.406 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.400 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.389 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.376 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.375 | a.28.1 | ACP-like |
| View | Download | 0.369 | a.3.1 | Cytochrome c |
| View | Download | 0.333 | a.4.1 | Homeodomain-like |
| View | Download | 0.324 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.313 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.311 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.311 | d.42.1 | POZ domain |
| View | Download | 0.307 | a.3.1 | Cytochrome c |
| View | Download | 0.303 | a.28.1 | ACP-like |
| View | Download | 0.288 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.264 | a.46.1 | Methionine synthase domain |
| View | Download | 0.263 | a.4.7 | Ribosomal protein L11, C-terminal domain |
| View | Download | 0.257 | d.95.2 | Homing endonucleases |
| View | Download | 0.253 | a.28.1 | ACP-like |
| View | Download | 0.247 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.246 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.238 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.233 | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.228 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.226 | a.28.1 | ACP-like |
| View | Download | 0.226 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.226 | a.4.1 | Homeodomain-like |
| View | Download | 0.223 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.219 | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.219 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.218 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.218 | d.75.1 | tRNA splicing endonuclease EdnA, N-terminal domain |
| View | Download | 0.215 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.214 | a.4.1 | Homeodomain-like |
| View | Download | 0.214 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.209 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.206 | a.64.1 | Saposin |
| View | Download | 0.205 | a.77.1 | DEATH domain |
| View | Download | 0.204 | a.118.14 | FliG |
| View | Download | 0.202 | a.134.1 | Fungal elicitin |
