| Protein: | VAM6 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1049 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VAM6.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1049] | [1..1049] |
|
|
5.0E-84 | [483..1019] | [321..880] |
|
|
7.0E-84 | [483..1019] | [321..880] |
|
|
3.0E-76 | [423..903] | [339..823] |
|
|
1.0E-73 | [358..1048] | [307..917] |
|
Region A: Residues: [1-420] |
1 11 21 31 41 51
| | | | | |
1 MLRAQKLHSL KSSDITAILP TEQSQKLVLA KKNGDVEVYS RDGNTLKLFQ VYPDLLQNAK 60
61 NDPLPPVIEN FYFANELSTI FAQCKETLIL LSTTNLHEYD RIIDRRGINH CWLFERSHKN 120
121 KEEKNTYLIY STINTAKMRV LIWEGRTYKN MMEASLSYRK ETIRSIYPGE TGITLATDLG 180
181 IYHWPYNKPS LIRIEKTVKN KFPKDMISAL TELKEQAEKV IEKKPKKNSH FDAQSFSSMD 240
241 RMSRKSSMSS LWYRTIRNER GNKIRYTFEL DGNDATPMII DGATKKIFKV ELMHNNEEPF 300
301 LIATDHATFS ESNSEFDHMQ YLSSNLLMLY NSSTIKFVDY ENGFTFLQQK IPEGIKWVKN 360
361 LSGTYFLVWT SNDEVQLFSY HVDDGSEDDD QESICGDIND PDFYQLWRKV LFYKFFIDSP 420
421
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [421-544] |
1 11 21 31 41 51
| | | | | |
1 HSKELCVSDN PEESLDICAM KLRDLTVMWC LRIFDKFQNY MVQLERSRNS RMIRSKCEEM 60
61 IIKSIFDLFI KFWAPPQLVI LKVFPSAISS LVLEITGQEH HCLLKEAEEV KETYDIPPHL 120
121 LNRW
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.775 | 0.172 | vacuolar membrane | a.25.1 | Ferritin-like |
| View | Download | 0.663 | 0.008 | vacuolar membrane | a.63.1 | Apolipophorin-III |
| View | Download | 0.521 | 0.007 | vacuolar membrane | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.805 | 0.005 | vacuolar membrane | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.545 | 0.003 | vacuolar membrane | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.502 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.497 | N/A | N/A | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.487 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.469 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.461 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.460 | N/A | N/A | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.455 | N/A | N/A | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.454 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.440 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.434 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.429 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.426 | N/A | N/A | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.419 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.418 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.410 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.409 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.387 | N/A | N/A | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.377 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.367 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.366 | N/A | N/A | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.364 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.353 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.351 | N/A | N/A | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.344 | N/A | N/A | a.146.1 | Telomeric repeat binding factor (TRF) dimerisation domain |
| View | Download | 0.341 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.338 | N/A | N/A | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.333 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.320 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.294 | N/A | N/A | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.292 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.289 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.285 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.277 | N/A | N/A | a.118.16 | Testis/brain RNA-binding protein (TB-RBP) |
| View | Download | 0.272 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.266 | N/A | N/A | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.263 | N/A | N/A | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.260 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.260 | N/A | N/A | a.84.1 | Scaffolding protein gpD of bacteriophage procapsid |
| View | Download | 0.256 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.256 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.253 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.252 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.251 | N/A | N/A | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.249 | N/A | N/A | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.246 | N/A | N/A | a.118.7 | 14-3-3 protein |
| View | Download | 0.238 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.232 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.232 | N/A | N/A | d.95.2 | Homing endonucleases |
| View | Download | 0.229 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.229 | N/A | N/A | d.81.1 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| View | Download | 0.229 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.228 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.226 | N/A | N/A | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.224 | N/A | N/A | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.219 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.217 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.217 | N/A | N/A | d.58.22 | TRADD, N-terminal domain |
| View | Download | 0.216 | N/A | N/A | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.210 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.210 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.209 | N/A | N/A | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.207 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.207 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.206 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.204 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.202 | N/A | N/A | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.201 | N/A | N/A | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.200 | N/A | N/A | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
|
Region A: Residues: [545-859] |
1 11 21 31 41 51
| | | | | |
1 CLPYLTDTRR HLQNLLSKEN DDESRITWCY RDREIKQSFD FFLISNHDDV DLNTMLTLID 60
61 TVLFKCYLYY NPPMVGPFIR VENHCDSHVI VTELKIRHMF KDLIDFYYKR GNHEEALKFL 120
121 TDLVDELEND NTDQKQRQKI DHGVKILVIY YLKKLSNPQL DVIFTYTDWL LNRHNDSIKE 180
181 ILSSIFFYDS QACSSRDHLK VYGYIKKFDK LLAIQYLEFA ISTFRLEGNK LHTVLIKLYL 240
241 ENLDIPSTRI KLKSLLETTS VYEPRTILKL LNDAIESGSD QLPTNQLNFV KYLKIFPLSK 300
301 LENHKEAVHI LLDEI
|
| Detection Method: | |
| Confidence: | 41.045757 |
| Match: | 1b89A_ |
| Description: | Clathrin heavy chain proximal leg segment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [860-974] |
1 11 21 31 41 51
| | | | | |
1 DDYKAATSYC NDVYQSDSTK GEELLLYLYS KLVSIYDSNR NSKLILNFLQ DHGSKLNSAE 60
61 IYKNLPQDIS LYDIGRVVSQ LLKKHTSKMD ETRLEKALLQ VELVATTYKL NERMS
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.826 | 0.067 | vacuolar membrane | a.118.8 | TPR-like |
| View | Download | 0.736 | 0.051 | vacuolar membrane | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.664 | 0.035 | vacuolar membrane | a.24.3 | Cytochromes |
| View | Download | 0.853 | 0.020 | vacuolar membrane | a.24.4 | Hemerythrin |
| View | Download | 0.634 | N/A | N/A | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.624 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.611 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.583 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.566 | N/A | N/A | a.7.8 | GAT domain |
| View | Download | 0.538 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.532 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.511 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.495 | N/A | N/A | c.53.1 | Resolvase-like |
| View | Download | 0.493 | N/A | N/A | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.480 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.474 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.471 | N/A | N/A | a.28.1 | ACP-like |
| View | Download | 0.464 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.449 | N/A | N/A | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.437 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.424 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.421 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.413 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.395 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.385 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.366 | N/A | N/A | a.118.6 | Protein prenylyltransferase |
| View | Download | 0.361 | N/A | N/A | a.118.13 | Arp2/3 complex 16 kDa subunit ARPC5 |
| View | Download | 0.356 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.354 | N/A | N/A | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.353 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.353 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.341 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.332 | N/A | N/A | a.141.1 | Frizzled cystein-rich domain |
| View | Download | 0.331 | N/A | N/A | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.330 | N/A | N/A | b.82.4 | Regulatory protein AraC |
| View | Download | 0.330 | N/A | N/A | d.130.1 | S-adenosylmethionine synthetase |
| View | Download | 0.318 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.313 | N/A | N/A | c.30.1 | PreATP-grasp domain |
| View | Download | 0.306 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.302 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.302 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.300 | N/A | N/A | c.57.1 | Molybdenum cofactor biosynthesis proteins |
| View | Download | 0.295 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.288 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.277 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.272 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.269 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.269 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.267 | N/A | N/A | d.55.1 | Ribosomal protein L22 |
| View | Download | 0.261 | N/A | N/A | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.261 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.259 | N/A | N/A | a.79.1 | Antitermination factor NusB |
| View | Download | 0.258 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.253 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.249 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.245 | N/A | N/A | a.126.1 | Serum albumin-like |
| View | Download | 0.245 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.244 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.244 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.243 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.241 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.241 | N/A | N/A | a.39.3 | Cloroperoxidase |
| View | Download | 0.237 | N/A | N/A | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.233 | N/A | N/A | c.95.1 | Thiolase-like |
| View | Download | 0.229 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.223 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.222 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.218 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.218 | N/A | N/A | a.65.1 | Annexin |
| View | Download | 0.216 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.215 | N/A | N/A | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.214 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.213 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.210 | N/A | N/A | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.210 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.208 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.207 | N/A | N/A | a.92.1 | Carbamoyl phosphate synthetase, large subunit connection domain |
| View | Download | 0.205 | N/A | N/A | a.39.2 | Insect pheromon/odorant-binding proteins |
| View | Download | 0.204 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.204 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.201 | N/A | N/A | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
|
Region A: Residues: [975-1049] |
1 11 21 31 41 51
| | | | | |
1 SYGVLSDSHK CPICKKVISN FGTDSISWFT REGRNIITHY NCGKVLQERF NAKNEKSSRI 60
61 KQKTLGEVIN ELNNK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.582 | 0.267 | vacuolar membrane | a.3.1 | Cytochrome c |
| View | Download | 0.783 | 0.069 | vacuolar membrane | a.60.1 | SAM/Pointed domain |
| View | Download | 0.685 | 0.009 | vacuolar membrane | a.60.4 | DNA repair protein Rad51, N-terminal domain |
| View | Download | 0.448 | 0.003 | vacuolar membrane | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.590 | N/A | N/A | a.60.1 | SAM/Pointed domain |
| View | Download | 0.428 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.427 | N/A | N/A | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.425 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.414 | N/A | N/A | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.387 | N/A | N/A | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.343 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.342 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.325 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.316 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.313 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.282 | N/A | N/A | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.275 | N/A | N/A | a.21.1 | HMG-box |
| View | Download | 0.255 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.243 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.243 | N/A | N/A | a.180.1 | N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |
| View | Download | 0.233 | N/A | N/A | a.17.1 | p8-MTCP1 |
| View | Download | 0.231 | N/A | N/A | a.22.1 | Histone-fold |
| View | Download | 0.218 | N/A | N/A | a.144.1 | PABC (PABP) domain |
| View | Download | 0.215 | N/A | N/A | b.34.1 | C-terminal domain of transcriptional repressors |
| View | Download | 0.205 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
