YRC Public Data Repository - Protein Structure Prediction

Protein:	LUG1
Organism:	Saccharomyces cerevisiae
Length:	153 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LUG1.

Description	E-value	Query Range	Subject Range
YC16_YEAST - UPF0743 protein YCR087C-A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YCR087C-A PE=1... LUG1 - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...	9.0E-47	[1..153]	[1..153]
gi\|16041815, gi\|... - gi\|8923398\|ref\|NP_060286.1\| Ly1 antibody reactive homolog [Homo sapiens], gi\|7020518\|dbj\|BAA91162.1\|... HGNC:26021\|Ensem... - antibody reactive homolog (mouse) gi\|208965202 - gi\|208965202\|dbj\|BAG72615.1\| Ly1 antibody reactive homolog [synthetic construct]	2.0E-46	[1..130]	[1..143]
gi\|18033305 - gi\|18033305\|gb\|AAL57050.1\|AF332588_1 cell growth-regulating nucleolar protein [Danio rerio]	2.0E-44	[1..133]	[1..146]
gi\|13384622, gi\|... - gi\|13384622\|ref\|NP_079557.1\| Ly1 antibody reactive clone [Mus musculus], gi\|12839441\|dbj\|BAB24554.1\|...	3.0E-44	[1..130]	[1..143]
CE01499 - cell growth regulating protein status:Confirmed UniProt:Q09464 protein_id:CAA86746.1	6.0E-42	[1..130]	[1..141]
UBA1C_ARATH - UBP1-associated proteins 1C OS=Arabidopsis thaliana GN=UBA1C PE=3 SV=2	7.0E-29	[1..72]	[1..71]
YH56_SCHPO - UPF0743 protein C215.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC215.06c PE=1 ... SPBC215.06c - human LYHRT homolog	1.0E-20	[8..74]	[6..71]

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Predicted Domain #1

Region A:
Residues: [1-153]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTFNCEVCN DTVPKKNTEK HYYRCPNAYY TCIDCSKTFE DGVSYKNHTS CISEDEKYQK  60
   61 ALYKGNKKQK QKQQQKQQQK QHQHQPVATP AKKVEKPVIK KAEKVEKTSN GIELHKGKSL 120
  121 YKILKTMKDK GAKKTFLKSL VVDSEGQIRY AKE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	1.72893576328611	bayes_pls_golite062009
nucleic acid binding	1.69485293197742	bayes_pls_golite062009
DNA binding	1.56529962350735	bayes_pls_golite062009
transcription regulator activity	1.34618935906821	bayes_pls_golite062009
transcription factor activity	0.482168429405299	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [68-153]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQKQKQQQKQ QQKQHQHQPV ATPAKKVEKP VIKKAEKVEK TSNGIELHKG KSLYKILKTM  60
   61 KDKGAKKTFL KSLVVDSEGQ IRYAKE