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View Structure Prediction Details

Protein: MATALPHA1, HMLALPHA1
Organism: Saccharomyces cerevisiae
Length: 175 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MATALPHA1, HMLALPHA1.

Description E-value Query
Range		 Subject
Range
MATALPHA1, HMLALPHA1 - Transcriptional co-activator involved in regulation of mating-type-specific gene expression; targets...
MTAL1_YEAST, HMA... - Mating-type protein ALPHA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MATALPHA1 PE=...
gi|190406385 - gi|190406385|gb|EDV09652.1| MTAL1_YEAST?Mating-type?protein?ALPHA1 [Saccharomyces cerevisiae RM11-1a...
 5.0E-63 [1..175] [1..175]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 4.0E-42 [1..157] [1..171]
MAT1_COCHE - Mating-type protein MAT-1 OS=Cochliobolus heterostrophus GN=MAT1 PE=3 SV=1
 4.0E-27 [53..144] [31..117]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 1.0E-26 [53..144] [31..117]
MAT1_COCCA - Mating-type protein MAT-1 OS=Cochliobolus carbonum GN=MAT1 PE=3 SV=1
 1.0E-26 [53..144] [31..117]
MATA_NEUCR - Mating-type protein A-1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257...
MATA_NEUCR - Mating-type protein A-1 OS=Neurospora crassa GN=mtA-1 PE=1 SV=2
 2.0E-26 [86..175] [40..115]
MAT1_COCCY - Mating-type protein MAT-1 OS=Cochliobolus cymbopogonis GN=MAT1 PE=3 SV=1
 5.0E-26 [53..144] [31..117]
MAT1_COCEL - Mating-type protein MAT-1 OS=Cochliobolus ellisii GN=MAT1 PE=3 SV=1
 5.0E-26 [53..144] [31..117]
MAT1_COCSA - Mating-type protein MAT-1 OS=Cochliobolus sativus GN=MAT1 PE=3 SV=1
 6.0E-26 [53..144] [31..117]
gi|4928164 - gi|4928164|gb|AAD33439.1|AF129740_2 mating type protein MAT-1/2 [Cochliobolus luttrellii]
 1.0E-25 [53..144] [31..117]

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Predicted Domain #1
Region A:
Residues: [1-175] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTSKPAFKI KNKASKSYRN TAVSKKLKEK RLAEHVRPSC FNIIRPLKKD IQIPVPSSRF  60
   61 LNKIQIHRIA SGSQNTQFRQ FNKTSIKSSK KYLNSFMAFR AYYSQFGSGV KQNVLSSLLA 120
  121 EEWHADKMQH GIWDYFAQQY NFINPGFGFV EWLTNNYAEV RGDGYWEDVF VHLAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
DNA binding 4.84246149108405 bayes_pls_golite062009
nucleic acid binding 4.73451137188048 bayes_pls_golite062009
transcription regulator activity 4.70526716815828 bayes_pls_golite062009
transcription factor activity 3.57291699480776 bayes_pls_golite062009
binding 3.45976454780353 bayes_pls_golite062009
sequence-specific DNA binding 2.64790748689391 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.54168984559574 bayes_pls_golite062009
transcription activator activity 1.46271038594364 bayes_pls_golite062009
chromatin binding 1.42879477692352 bayes_pls_golite062009
transcription repressor activity 1.35292098889847 bayes_pls_golite062009
protein binding 1.06660874927515 bayes_pls_golite062009
transcription factor binding 0.97374076531363 bayes_pls_golite062009
four-way junction DNA binding 0.646384703124195 bayes_pls_golite062009
DNA bending activity 0.428738547626155 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.0671309267769598 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle