| Protein: | NFS1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 497 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NFS1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..497] | [1..497] |
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0.0 | [1..497] | [1..490] |
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0.0 | [93..497] | [6..412] |
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0.0 | [99..497] | [4..404] |
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0.0 | [99..497] | [4..404] |
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0.0 | [99..497] | [4..404] |
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0.0 | [42..497] | [24..488] |
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0.0 | [46..497] | [30..484] |
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0.0 | [41..497] | [8..457] |
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Region A: Residues: [1-70] |
1 11 21 31 41 51
| | | | | |
1 MLKSTATRSI TRLSQVYNVP AATYRACLVS RRFYSPPAAG VKLDDNFSLE THTDIQAAAK 60
61 AQASARASAS
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.629 | a.74.1 | Cyclin-like |
| View | Download | 0.717 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.552 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.729 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.439 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.611 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.503 | d.58.43 | Mechanosensitive channel protein MscS (YggB), C-terminal domain |
| View | Download | 0.494 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.435 | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.432 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.390 | a.74.1 | Cyclin-like |
| View | Download | 0.373 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.362 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.353 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.343 | a.60.12 | DNA polymerase beta-like, second domain |
| View | Download | 0.330 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.321 | a.5.2 | UBA-like |
| View | Download | 0.313 | d.58.36 | Sulfite reductase, domains 1 and 3 |
| View | Download | 0.306 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.285 | a.60.12 | DNA polymerase beta-like, second domain |
| View | Download | 0.257 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.244 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.237 | a.5.2 | UBA-like |
| View | Download | 0.237 | d.66.1 | Alpha-L RNA-binding motif |
| View | Download | 0.235 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.233 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.227 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.220 | a.83.1 | Guanido kinase N-terminal domain |
| View | Download | 0.217 | a.57.1 | Protein HNS-dependent expression A; HdeA |
|
Region A: Residues: [71-104] |
1 11 21 31 41 51
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1 GTTPDAVVAS GSTAMSHAYQ ENTGFGTRPI YLDM
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Region B: Residues: [358-497] |
1 11 21 31 41 51
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1 NDQAHIKRLS DKLVKGLLSA EHTTLNGSPD HRYPGCVNVS FAYVEGESLL MALRDIALSS 60
61 GSACTSASLE PSYVLHALGK DDALAHSSIR FGIGRFSTEE EVDYVVKAVS DRVKFLRELS 120
121 PLWEMVQEGI DLNSIKWSGH
|
| Detection Method: | |
| Confidence: | 860.9897 |
| Match: | 1ecxA_ |
| Description: | NifS-like protein/selenocysteine lyase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 3.40354781002256 | bayes_pls_golite062009 |
| glycine dehydrogenase (decarboxylating) activity | 3.40354781002256 | bayes_pls_golite062009 |
| transferase activity | 2.59075614411581 | bayes_pls_golite062009 |
| L-aspartate:2-oxoglutarate aminotransferase activity | 2.30133284041702 | bayes_pls_golite062009 |
| catalytic activity | 2.29878871754893 | bayes_pls_golite062009 |
| transcription regulator activity | 1.67701710033155 | bayes_pls_golite062009 |
| DNA binding | 1.4774443071095 | bayes_pls_golite062009 |
| nucleic acid binding | 1.39741122443159 | bayes_pls_golite062009 |
| cysteine desulfurase activity | 1.30923778688541 | bayes_pls_golite062009 |
| transferase activity, transferring nitrogenous groups | 1.28316822767388 | bayes_pls_golite062009 |
| transaminase activity | 1.24990480711889 | bayes_pls_golite062009 |
| transcription factor activity | 1.15775909410582 | bayes_pls_golite062009 |
| binding | 1.09053123792737 | bayes_pls_golite062009 |
| L-alanine:2-oxoglutarate aminotransferase activity | 1.06988190956423 | bayes_pls_golite062009 |
| alanine-oxo-acid transaminase activity | 1.06988190956423 | bayes_pls_golite062009 |
| ligase activity | 0.827063849687833 | bayes_pls_golite062009 |
| structural molecule activity | 0.754675308623467 | bayes_pls_golite062009 |
| carbon-sulfur lyase activity | 0.698312655247044 | bayes_pls_golite062009 |
| 5-aminolevulinate synthase activity | 0.54326874956263 | bayes_pls_golite062009 |
| cystathionine gamma-lyase activity | 0.505859361763689 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 0.50269055590758 | bayes_pls_golite062009 |
| cystathionine beta-lyase activity | 0.27933426619091 | bayes_pls_golite062009 |
| glycine hydroxymethyltransferase activity | 0.271623203801431 | bayes_pls_golite062009 |
| O-phospho-L-serine:2-oxoglutarate aminotransferase activity | 0.234399054481664 | bayes_pls_golite062009 |
| RNA binding | 0.222777224430863 | bayes_pls_golite062009 |
| vitamin B6 binding | 0.16957228630576 | bayes_pls_golite062009 |
| pyridoxal phosphate binding | 0.16957228630576 | bayes_pls_golite062009 |
| methyltransferase activity | 0.103986924428507 | bayes_pls_golite062009 |
| sulfurtransferase activity | 0.0450490929307473 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 0.0254276656964899 | bayes_pls_golite062009 |
|
Region A: Residues: [105-357] |
1 11 21 31 41 51
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1 QATTPTDPRV LDTMLKFYTG LYGNPHSNTH SYGWETNTAV ENARAHVAKM INADPKEIIF 60
61 TSGATESNNM VLKGVPRFYK KTKKHIITTR TEHKCVLEAA RAMMKEGFEV TFLNVDDQGL 120
121 IDLKELEDAI RPDTCLVSVM AVNNEIGVIQ PIKEIGAICR KNKIYFHTDA AQAYGKIHID 180
181 VNEMNIDLLS ISSHKIYGPK GIGAIYVRRR PRVRLEPLLS GGGQERGLRS GTLAPPLVAG 240
241 FGEAARLMKK EFD
|
| Detection Method: | |
| Confidence: | 860.9897 |
| Match: | 1ecxA_ |
| Description: | NifS-like protein/selenocysteine lyase |
| Matching Structure (courtesy of the PDB): |
|
