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View Structure Prediction Details

Protein: SSH1
Organism: Saccharomyces cerevisiae
Length: 490 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSH1.

Description E-value Query
Range
Subject
Range
CE14954 - protein transport protein SEC61 alpha subunit status:Confirmed UniProt:O18239 protein_id:CAB16516.1
0.0 [3..480] [2..471]
S61A2_ONCMY - Protein transport protein Sec61 subunit alpha isoform B OS=Oncorhynchus mykiss GN=sec61ab PE=2 SV=3
0.0 [3..480] [2..474]
S61A2_MOUSE - Protein transport protein Sec61 subunit alpha isoform 2 OS=Mus musculus GN=Sec61a2 PE=2 SV=3
gi|34876835 - gi|34876835|ref|XP_341559.1| PREDICTED: similar to Sec61, alpha subunit 2 [Rattus norvegicus]
S61A2_BOVIN - Protein transport protein Sec61 subunit alpha isoform 2 OS=Bos taurus GN=SEC61A2 PE=2 SV=3
SEC61A2 - Sec61 alpha 2 subunit (S. cerevisiae)
0.0 [3..480] [2..474]
gi|13936273, gi|... - gi|24119237|ref|NP_705945.1| Sec61 alpha like 1 [Danio rerio], gi|13936273|gb|AAK40295.1| Sec61 alph...
0.0 [4..480] [3..474]
gi|6581004 - gi|6581004|gb|AAF18411.1|AF190652_1 putative integral membrane protein [Phaseolus vulgaris]
0.0 [2..474] [3..470]
gi|19335712 - gi|19335712|gb|AAL85625.1| probable transport protein Sec61 alpha subunit [Aedes aegypti]
0.0 [3..480] [2..474]
S61A1_MOUSE - Protein transport protein Sec61 subunit alpha isoform 1 OS=Mus musculus GN=Sec61a1 PE=1 SV=2
gi|206886 - gi|206886|gb|AAA42125.1| sec61-like protein [Rattus sp.]
ENSPTRT00000028666 - null
S61A1_PONPY - Protein transport protein Sec61 subunit alpha isoform 1 - Pongo pygmaeus (Orangutan)
gi|157170276, gi... - gi|162319052|gb|AAI56689.1| Sec61 alpha 1 subunit (S. cerevisiae) [synthetic construct], gi|15717027...
CCDS3046.1_1 - null
S61A1_PONAB - Protein transport protein Sec61 subunit alpha isoform 1 OS=Pongo abelii GN=SEC61A1 PE=2 SV=3
SEC61A1 - Sec61 alpha 1 subunit (S. cerevisiae)
ENSCJAT00000010395 - null
S61A1_RAT - Protein transport protein Sec61 subunit alpha isoform 1 OS=Rattus norvegicus GN=Sec61a1 PE=2 SV=2
0.0 [4..480] [3..474]
S61A1_CANLF - Protein transport protein Sec61 subunit alpha isoform 1 OS=Canis lupus familiaris GN=SEC61A1 PE=1 SV...
0.0 [4..480] [3..474]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGFRLIDIV KPILPILPEV ELPFEKLPFD DKIVYTIFAG LIYLFAQFPL VGLPKATTPN  60
   61 VNDPIYFLRG VFGC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.339 0.029 cotranslational protein targeting to membrane a.77.1 DEATH domain
View Download 0.362 0.008 cotranslational protein targeting to membrane a.7.7 BAG domain
View Download 0.453 0.005 cotranslational protein targeting to membrane f.15.1 Small-conductance potassium channel
View Download 0.495 0.003 cotranslational protein targeting to membrane a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.330 0.002 cotranslational protein targeting to membrane a.7.6 Ribosomal protein S20
View Download 0.313 N/A N/A a.28.1 ACP-like
View Download 0.300 N/A N/A a.22.1 Histone-fold
View Download 0.289 N/A N/A a.60.8 HRDC-like
View Download 0.278 N/A N/A a.105.1 FIS-like
View Download 0.253 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.246 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.246 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.242 N/A N/A a.112.1 Description not found.
View Download 0.233 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.232 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.231 N/A N/A a.28.1 ACP-like
View Download 0.211 N/A N/A d.70.1 Yest killer toxins
View Download 0.206 N/A N/A a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.205 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.201 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region

Predicted functions:

Term Confidence Notes
ribonucleoprotein binding 5.96221631042313 bayes_pls_golite062009
protein transporter activity 5.55929343005534 bayes_pls_golite062009
transporter activity 3.32223562584466 bayes_pls_golite062009
substrate-specific transporter activity 3.22714325269757 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 2.12732472524264 bayes_pls_golite062009
macromolecule transmembrane transporter activity 2.12732472524264 bayes_pls_golite062009
protein transmembrane transporter activity 1.76187269823414 bayes_pls_golite062009
transmembrane transporter activity 1.67782980643723 bayes_pls_golite062009
binding 1.4562802789412 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.42890247609405 bayes_pls_golite062009
primary active transmembrane transporter activity 1.15847548838424 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.15316743403707 bayes_pls_golite062009
active transmembrane transporter activity 1.10003802565492 bayes_pls_golite062009
peptide transporter activity 1.01893828721893 bayes_pls_golite062009
protein binding 0.674651002700028 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [75-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPRTLLEFGL FPNISSGLIL QLLAGLKVIK VNFKIQSDRE LFQSLTKVFA IVQYVILTNI  60
   61 FIFAGYFGDD LSVVQIGLIN FQLVGAGIFT TLLAEVIDKG FGFSSGAMII NTVVIATNLV 120
  121 ADTFGVSQIK VGEDDQTEAQ GALINLIQGL RSKHKTFIGG IISAFNRDYL PNLTTTIIVL 180
  181 AIAIIVCYLQ SVRVELPIRS TRARGTNNVY PIKLLYTGCL SVLFSYTILF YIHIFAFVLI 240
  241 QLVAKNEPTH IICKIMGHYE NANNLLAVPT FPLSLLAPPT SFFKGVTQQP LTFITYSAFI 300
  301 LVTGIWFADK WQAISGSSAR DVALEFKDQG ITLMGRREQN VAKELNKVIP IAAVTGASVL 360
  361 SLITVIGESL GLKGKAAGIV VGIAGGFSLL EVITIEYQQS GGQSALNQVL GVPGAM

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 6.142668
Match: PF00344
Description: eubacterial secY protein

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle