YRC Public Data Repository - Protein Structure Prediction

Protein:	MCX1
Organism:	Saccharomyces cerevisiae
Length:	520 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCX1.

Description	E-value	Query Range	Subject Range
CLPX_YEAST - ATP-dependent clpX-like chaperone, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S... MCX1 - Mitochondrial matrix protein; putative ATP-binding chaperone with non-proteolytic function; similar ...	0.0	[1..520]	[1..520]
gi\|6513847 - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis] gi\|57640604, gi\|... - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis], gi\|57640604\|ref\|YP_183082.1\| cell d...	0.0	[35..500]	[147..641]
gi\|3257095, gi\|1... - gi\|3257095\|dbj\|BAA29778.1\| 840aa long hypothetical cell division control protein (transitional endop... gi\|7435754 - pir\|\|H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyr...	0.0	[37..507]	[152..653]
gi\|7435762, gi\|5... - pir\|\|D75046 transitional endoplasmic reticulum atpase PAB1478 - Pyrococcus abyssi (strain Orsay), gi... gi\|5458778, gi\|1... - gi\|5458778\|emb\|CAB50265.1\| ATPase of the AAA+ family [Pyrococcus abyssi GE5], gi\|14521559\|ref\|NP_127...	0.0	[37..499]	[152..643]
gi\|18159541, gi\|... - gi\|18312110\|ref\|NP_558777.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	0.0	[39..500]	[112..551]
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1	0.0	[83..514]	[191..594]
gi\|18977335, gi\|... - gi\|18977335\|ref\|NP_578692.1\| cell division protein CDC48 [Pyrococcus furiosus DSM 3638], gi\|18893012...	0.0	[41..507]	[153..650]
CD48D_ARATH - Cell division control protein 48 homolog D OS=Arabidopsis thaliana GN=CDC48D PE=1 SV=1	0.0	[83..514]	[191..594]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[83..507]	[223..619]
SAV_SULAC - Protein SAV OS=Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIM... SAV_SULAC - Protein SAV OS=Sulfolobus acidocaldarius GN=sav PE=3 SV=2	0.0	[81..500]	[193..584]

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Predicted Domain #1

Region A:
Residues: [1-520]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKSASQNFF RAYSSRIGRY AATASGKLAQ SRLSNIPTPK ALKKFLDEYI VGQEIGKKVL  60
   61 SVAVYNHYLR INDKQKKGEL QRQRELMERE KIADDRDEPI FSGNSESKAG WRNLQRQFNL 120
  121 AGREVDEDLE LSKSNVLVVG PSGSGKTLLA TTLAKILNVP IAITDCTQLT QAGYIGEDVE 180
  181 VCIERLLVNA EFDVARAEKG IIVLDEIDKL AKPAASIGTK DVSGEGVQQS LLKIIEGHKV 240
  241 EITVKRPVKH DIDGQKNQTT TKKDEVFVVD TSNILFMIMG AFVGLDKHIV KRIEDMKKIQ 300
  301 KAGESVESSN SKEVEKERAK KFRFSNTLEQ VELDNGKKVC ALDLTTPTDL VSFGLIPELI 360
  361 GRVPIITALQ PLQRDDLFHI LKEPKNALLD QYEYIFKQFG VRLCVTQKAL KKVAQFALKE 420
  421 GTGARGLRGI MERLLLNVNY DCPGSNIAYV LIDEATVDSL QETEHSLASQ VDVKYYSGDE 480
  481 KDSLIRDVSE EDKKLGVMLE KELGHSANIH TPTIPKRSLT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	259.9897
Match:	1g3iA_
Description:	HslU
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.55157966585974	bayes_pls_golite062009
binding	1.62320027057768	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
purine nucleotide binding	0.569910969126728	bayes_pls_golite062009
purine ribonucleotide binding	0.568840867400671	bayes_pls_golite062009
ribonucleotide binding	0.568779924702229	bayes_pls_golite062009
nucleotide binding	0.564275755355315	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.546796591575762	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.543610140926125	bayes_pls_golite062009
pyrophosphatase activity	0.540750418412449	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.517457589081898	bayes_pls_golite062009
nucleic acid binding	0.318452816722389	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009
helicase activity	0.0450969969658499	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: