YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: MSI1
Organism: Saccharomyces cerevisiae
Length: 422 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSI1.

Description E-value Query
Range
Subject
Range
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [4..417] [846..1251]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..422] [951..1368]

Back

Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQCAKDITH EASSIPIDLQ ERYSHWKKNT KLLYDYLNTN STKWPSLTCQ FFPDLDTTSD  60
   61 EHRILLSSFT SSQKPEDETI YISKISTLGH IKWSSLNNFD MDEMEFKPEN S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.0
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
acetyltransferase activity 3.85374902981345 bayes_pls_golite062009
acyltransferase activity 3.35098520158193 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.31615347567536 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.14917998298348 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.79445416141967 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
transcription repressor activity 2.29049708962212 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.18628561734369 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
dynein binding 1.62099593211487 bayes_pls_golite062009
transcription corepressor activity 1.41752877005447 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
cytoskeletal protein binding 1.19593750149343 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
transcription initiation factor activity 1.01962930136588 bayes_pls_golite062009
0.88172763425403 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.676924760416604 bayes_pls_golite062009
DNA-dependent ATPase activity 0.625780732991652 bayes_pls_golite062009
actin binding 0.529861581509437 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
DNA polymerase activity 0.428715007921149 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.426429095658617 bayes_pls_golite062009
kinase activity 0.387572734234845 bayes_pls_golite062009
snoRNA binding 0.347797037104681 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
transporter activity 0.284701931503833 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226335610368636 bayes_pls_golite062009
DNA helicase activity 0.220747580531792 bayes_pls_golite062009
enzyme regulator activity 0.161639372576406 bayes_pls_golite062009
chromatin binding 0.151977098745772 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [112-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRFPSKHLVN DISIFFPNGE CNRARYLPQN PDIIAGASSD GAIYIFDRTK HGSTRIRQSK  60
   61 ISHPFETKLF GSHGVIQDVE AMDTSSADIN EATSLAWNLQ QEALLLSSHS NGQVQVWDIK 120
  121 QYSHENPIID LPLVSINSDG TAVNDVTWMP THDSLFAACT EGNAVSLLDL RTKKEKLQSN 180
  181 REKHDGGVNS CRFNYKNSLI LASADSNGRL NLWDIRNMNK SPIATMEHGT SVSTLEWSPN 240
  241 FDTVLATAGQ EDGLVKLWDT SCEETIFTHG GHMLGVNDIS WDAHDPWLMC SVANDNSVHI 300
  301 WKPAGNLVGH S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 132.10721
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle