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View Structure Prediction Details

Protein: SMP1
Organism: Saccharomyces cerevisiae
Length: 452 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMP1.

Description E-value Query
Range
Subject
Range
SMP1_YEAST - Transcription factor SMP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SMP1 PE=1 SV=1
SMP1 - Putative transcription factor involved in regulating the response to osmotic stress; member of the M...
0.0 [1..452] [1..452]
gi|3688591 - gi|3688591|dbj|BAA33458.1| MADS box transcription factor [Triticum aestivum]
4.0E-71 [1..255] [1..253]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-70 [1..257] [1..239]
gi|6092009 - gi|6092009|dbj|BAA85630.1| GpMADS3 [Gnetum parvifolium]
2.0E-69 [1..237] [1..248]
gi|13958339 - gi|13958339|gb|AAK50865.1|AF372840_1 mads1 [Poa annua]
7.0E-68 [1..255] [1..254]
gi|5019456 - gi|5019456|emb|CAB44455.1| putative MADS domain transcription factor GGM9 [Gnetum gnemon]
2.0E-67 [1..237] [1..249]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRRKIEIEP IKDDRNRTVT FIKRKAGLFK KAHELSVLCQ VDIAVIILGS NNTFYEYSSV  60
   61 DMSNLLNVHQ NNTDLPHNII 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 189.616428
Match: 1egwA_
Description: Mef2a core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.47820295830817 bayes_pls_golite062009
DNA binding 4.34885522982729 bayes_pls_golite062009
nucleic acid binding 4.22473647889076 bayes_pls_golite062009
sequence-specific DNA binding 3.75742221961238 bayes_pls_golite062009
binding 3.73009730829487 bayes_pls_golite062009
transcription factor activity 3.68208249443337 bayes_pls_golite062009
transcription activator activity 2.70980744336671 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.63280961628615 bayes_pls_golite062009
protein binding 2.32692027935469 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.37351258349543 bayes_pls_golite062009
DNA bending activity 0.167327205417291 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [81-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPSDYGDYVK KPRVVLNERK RRRRRATVLQ PASHSGSCTV SSQDSSSVQN NGNLSAPLAS  60
   61 NDAGNAGVST PLVHCHGAIS RSGSNHSDCA RNSADYQMLQ GGLNSGGSFH ANDYKESVDQ 120
  121 QHVANEAIHR NFMNKRIRPD THLLLSESNH SNYHNFYPSP YENLPKPSLP ASLVGNIPSF 180
  181 QSQFVQVIPA NSNPMGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [278-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFNGTGDSES FEAKQKIHPT VAISNTLEGP APVQAMVHHL HQLNSNRGKL SGKPYLKLNI  60
   61 PKATNDACQR SPAMYSGTAS PKTDVQATPN QMLASNMSSP LSRSKFLGFK NNDMDDLYHN 120
  121 GRCGSTYVNN KTFFLKPPIG RPPKFPKSPS SSIVVFPSSV ASSTLKSTSS TNSPD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [348-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPAMYSGTAS PKTDVQATPN QMLASNMSSP LSRSKFLGFK NNDMDDLYHN GRCGSTYVNN  60
   61 KTFFLKPPIG RPPKFPKSPS SSIVVFPSSV ASSTLKSTSS TNSPD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle