YRC Public Data Repository - Protein Structure Prediction

Protein:	MRPS9
Organism:	Saccharomyces cerevisiae
Length:	278 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPS9.

Description	E-value	Query Range	Subject Range
RT09_YEAST - 37S ribosomal protein S9, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=... MRPS9 - Mitochondrial ribosomal protein of the small subunit	2.0E-89	[1..278]	[1..278]
RT09_KLUMA - 37S ribosomal protein S9, mitochondrial OS=Kluyveromyces marxianus GN=MRPS9 PE=3 SV=1	2.0E-82	[1..278]	[1..292]
RT09_CANAL - 40S ribosomal protein S9, mitochondrial OS=Candida albicans GN=MRPS9 PE=2 SV=1 RT09_CANAL - 37S ribosomal protein S9, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MRPS9...	1.0E-77	[6..278]	[58..336]
gi\|220949328 - gi\|220949328\|gb\|ACL87207.1\| mRpS9-PA [synthetic construct] mRpS9-PA - The gene mitochondrial ribosomal protein S9 is referred to in FlyBase by the symbol Dmel\mRpS9 (CG29...	1.0E-69	[9..278]	[119..395]
CE24890 - status:Confirmed UniProt:P34388 protein_id:AAK84520.1	7.0E-64	[10..278]	[337..633]
RS9_RHIME - 30S ribosomal protein S9 OS=Rhizobium meliloti (strain 1021) GN=rpsI PE=3 SV=1 RS9_RHIME - 30S ribosomal protein S9 OS=Rhizobium meliloti GN=rpsI PE=3 SV=1	1.0E-48	[131..278]	[8..155]
RS9_CAUCR - 30S ribosomal protein S9 OS=Caulobacter crescentus (strain ATCC 19089 / CB15) GN=rpsI PE=3 SV=1 RS9_CAUCR - 30S ribosomal protein S9 OS=Caulobacter crescentus GN=rpsI PE=3 SV=1 RS9_CAUCN - 30S ribosomal protein S9 OS=Caulobacter crescentus (strain NA1000 / CB15N) GN=rpsI PE=3 SV=1	7.0E-48	[135..278]	[14..157]
RS9_AGRFC - 30S ribosomal protein S9 OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=rpsI PE=3 SV=1 gi\|25294629, gi\|... - gi\|25294633\|pir\|\|AI2729 30S ribosomal protein S9 [imported] - Agrobacterium tumefaciens (strain C58,...	2.0E-47	[137..278]	[14..155]
RS9_LISMC - 30S ribosomal protein S9 OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=rpsI PE=3 SV=1 gi\|254825043 - gi\|254825043\|ref\|ZP_05230044.1\| 30S ribosomal protein S9 [Listeria monocytogenes FSL J1-194] gi\|254854199 - gi\|254854199\|ref\|ZP_05243547.1\| 30S ribosomal protein S9 [Listeria monocytogenes FSL R2-503] gi\|254877846 - gi\|254877846\|ref\|ZP_05250556.1\| 30S ribosomal protein S9 [Listeria monocytogenes FSL J2-071] gi\|254992717 - gi\|254992717\|ref\|ZP_05274907.1\| 30S ribosomal protein S9 [Listeria monocytogenes FSL J2-064] gi\|255022865 - gi\|255022865\|ref\|ZP_05294851.1\| 30S ribosomal protein S9 [Listeria monocytogenes FSL J1-208] gi\|255520579 - gi\|255520579\|ref\|ZP_05387816.1\| 30S ribosomal protein S9 [Listeria monocytogenes FSL J1-175] RS9_LISIN - 30S ribosomal protein S9 OS=Listeria innocua GN=rpsI PE=3 SV=1 RS9_LISMF - 30S ribosomal protein S9 OS=Listeria monocytogenes serotype 4b (strain F2365) GN=rpsI PE=3 SV=1 RS9_LISIN - 30S ribosomal protein S9 OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=rpsI PE=3 SV=1 RS9_LISMC - 30S ribosomal protein S9 OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=rpsI PE=3 SV=1 gi\|254871298, gi... - gi\|254871298\|ref\|ZP_05244008.1\| 30S ribosomal protein S9 [Listeria monocytogenes FSL N1-017], gi\|153... gi\|254931134, gi... - gi\|254931134\|ref\|ZP_05264493.1\| 30S ribosomal protein S9 [Listeria monocytogenes HPB2262], gi\|153204... gi\|47018096, gi\|... - gi\|47093536\|ref\|ZP_00231297.1\| ribosomal protein S9 [Listeria monocytogenes str. 4b H7858], gi\|47018... RS9_LISMH - 30S ribosomal protein S9 OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=rpsI PE=3 SV=1	3.0E-47	[151..278]	[3..130]

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Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSRLSLFRR AALAPAPMRM SFRTIYQKTE DELPRRIVPK LATFYSANPN HEDRINRLER  60
   61 LLRKYIKLPS QNNNEAQQTK APWISFDEYA LIGGGTKLKP TQYTQLLYML NKLHNIDPQL 120
  121 TNDEITSELS QYYKKSSMLS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.425	a.118.9	ENTH/VHS domain
View	Download	0.335	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.430	c.54.1	IIA domain of mannose transporter, IIA-Man
View	Download	0.430	c.54.1	IIA domain of mannose transporter, IIA-Man
View	Download	0.425	a.118.9	ENTH/VHS domain
View	Download	0.351	a.118.9	ENTH/VHS domain
View	Download	0.347	a.118.13	Arp2/3 complex 16 kDa subunit ARPC5
View	Download	0.347	a.118.13	Arp2/3 complex 16 kDa subunit ARPC5
View	Download	0.335	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.293	a.74.1	Cyclin-like
View	Download	0.278	a.131.1	Peridinin-chlorophyll protein
View	Download	0.275	c.56.3	Peptidyl-tRNA hydrolase
View	Download	0.275	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.268	a.39.2	Insect pheromon/odorant-binding proteins
View	Download	0.255	a.1.1	Globin-like
View	Download	0.221	a.78.1	Fatty acid responsive transcription factor FadR, C-terminal domain
View	Download	0.216	a.69.2	Ypt/Rab-GAP domain of gyp1p
View	Download	0.209	d.58.39	Glutamyl tRNA-reductase catalytic, N-terminal domain
View	Download	0.209	a.118.8	TPR-like
View	Download	0.208	d.14.1	Ribosomal protein S5 domain 2-like

Predicted Domain #2

Region A:
Residues: [141-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNIKIKTLDE FGRSIAVGKR KSSTAKVFVV RGTGEILVNG RQLNDYFLKM KDRESIMYPL  60
   61 QVIESVGKYN IFATTSGGGP TGQAESIMHA IAKALVVFNP LLKSRLHKAG VLTRDYRHVE 120
  121 RKKPGKKKAR KMPTWVKR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	264.70927
Match:	1fjgI_
Description:	Ribosomal protein S9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	7.32829196949019	bayes_pls_golite062009
structural molecule activity	6.75880680396215	bayes_pls_golite062009
3'-5'-exoribonuclease activity	1.56111033008721	bayes_pls_golite062009
RNA binding	1.40868766468494	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.35935222635763	bayes_pls_golite062009
exoribonuclease activity	1.31205157616894	bayes_pls_golite062009
3'-5' exonuclease activity	1.10842504252923	bayes_pls_golite062009
binding	0.923114523007774	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
nucleic acid binding	0.555181608481691	bayes_pls_golite062009
protein binding	0.398523921130957	bayes_pls_golite062009
transcription regulator activity	0.368412900600617	bayes_pls_golite062009
ribonuclease activity	0.19921800066954	bayes_pls_golite062009
DNA binding	0.0880977286684361	bayes_pls_golite062009
mRNA binding	0.0491645692672305	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	6.9430052008157E-5	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: