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View Structure Prediction Details

Protein: RDH54
Organism: Saccharomyces cerevisiae
Length: 958 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RDH54.

Description E-value Query
Range
Subject
Range
CHD5 - chromodomain helicase DNA binding protein 5
gi|151555557, gi... - gi|151555557|gb|AAI48804.1| Chromodomain helicase DNA binding protein 5 [synthetic construct], gi|14...
0.0 [38..958] [448..1313]
kis-PA - The gene kismet is referred to in FlyBase by the symbol Dmel\kis (CG3696, FBgn0086902). It is a prot...
0.0 [10..920] [1700..2630]
gi|45384078, gi|... - gi|996020|emb|CAA62832.1| BRM protein [Gallus gallus], gi|45384078|ref|NP_990470.1| SWI/SNF related,...
0.0 [2..943] [421..1337]

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Predicted Domain #1
Region A:
Residues: [1-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVISVKPRR REKILQEVKN SSVYQTVFDS GTTQMQIPKY ENKPFKPPRR VGSNKYTQLK  60
   61 PTATAVTTAP ISKAKVTVNL KRSISAGPTL NLAKKPNNLS SNENTRYFTI MYRKPTTKKH 120
  121 KTWSGDGYAT LKASSDKLCF YNEAGKFLGS SMLPSDSDSL FETLFKAGSN EVQLDYELKE 180
  181 NAEIRSAKEA LSQNMGNPSP PTTSTTETVP STKNDGGKYQ MPLSQLFSLN TVKRFKSVTK 240
  241 QTNEHMTTVP KTSQNSKAKK YYPVFDVNK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [270-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDNPIVMNKN AAAEVDVIVD PLLGKFLRPH QREGVKFMYD CLMGLARPTI ENPDIDCTTK  60
   61 SLVLENDSD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [339-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISGCLLADDM GLGKTLMSIT LIWTLIRQTP FASKVSCSQS GIPLTGLCKK ILVVCPVTLI  60
   61 GNWKREFGKW LNLSRIGVLT LSSRNSPDMD KMAVRNFLKV QRTYQVLIIG YEKLLSVSEE 120
  121 LEKNKHLIDM LVCDEGHRLK NGASKILNTL KSLDIRRKLL LTGTPIQNDL NEFFTIIDFI 180
  181 NPGILG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.96
Match: 1gm5A
Description: RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [525-656]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFASFKRRFI IPITRARDTA NRYNEELLEK GEERSKEMIE ITKRFILRRT NAILEKYLPP  60
   61 KTDIILFCKP YSQQILAFKD ILQGARLDFG QLTFSSSLGL ITLLKKVCNS PGLVGSDPYY 120
  121 KSHIKDTQSQ DS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.39794
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [657-958]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSRSLNSGKL KVLMTLLEGI RKGTKEKVVV VSNYTQTLDI IENLMNMAGM SHCRLDGSIP  60
   61 AKQRDSIVTS FNRNPAIFGF LLSAKSGGVG LNLVGRSRLI LFDNDWNPSV DLQAMSRIHR 120
  121 DGQKKPCFIY RLVTTGCIDE KILQRQLMKN SLSQKFLGDS EMRNKESSND DLFNKEDLKD 180
  181 LFSVHTDTKS NTHDLICSCD GLGEEIEYPE TNQQQNTVEL RKRSTTTWTS ALDLQKKMNE 240
  241 AATNDDAKKS QYIRQCLVHY KHIDPARQDE LFDEVITDSF TELKDSITFA FVKPGEICLR 300
  301 EQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1c4oA_
Description: Nucleotide excision repair enzyme UvrB
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle