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Protein Overview: RDH54

General Information:
Name(s) found: RDH54 / YBR073W [SGD]
Description(s) found:
Found 15 descriptions.
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  • DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 958 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: reciprocal meiotic recombination [IGILink to PubMed articleLink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    heteroduplex formation [IDALink to PubMed article]
    meiotic sister chromatid segregation [IMPLink to PubMed article]
    double-strand break repair via break-induced replication [TASLink to PubMed article]
    Molecular Function: DNA-dependent ATPase activity [IDALink to PubMed article]
    DNA topoisomerase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVISVKPRR REKILQEVKN SSVYQTVFDS GTTQMQIPKY ENKPFKPPRR VGSNKYTQLK  60
   61 PTATAVTTAP ISKAKVTVNL KRSISAGPTL NLAKKPNNLS SNENTRYFTI MYRKPTTKKH 120
  121 KTWSGDGYAT LKASSDKLCF YNEAGKFLGS SMLPSDSDSL FETLFKAGSN EVQLDYELKE 180
  181 NAEIRSAKEA LSQNMGNPSP PTTSTTETVP STKNDGGKYQ MPLSQLFSLN TVKRFKSVTK 240
  241 QTNEHMTTVP KTSQNSKAKK YYPVFDVNKI DNPIVMNKNA AAEVDVIVDP LLGKFLRPHQ 300
  301 REGVKFMYDC LMGLARPTIE NPDIDCTTKS LVLENDSDIS GCLLADDMGL GKTLMSITLI 360
  361 WTLIRQTPFA SKVSCSQSGI PLTGLCKKIL VVCPVTLIGN WKREFGKWLN LSRIGVLTLS 420
  421 SRNSPDMDKM AVRNFLKVQR TYQVLIIGYE KLLSVSEELE KNKHLIDMLV CDEGHRLKNG 480
  481 ASKILNTLKS LDIRRKLLLT GTPIQNDLNE FFTIIDFINP GILGSFASFK RRFIIPITRA 540
  541 RDTANRYNEE LLEKGEERSK EMIEITKRFI LRRTNAILEK YLPPKTDIIL FCKPYSQQIL 600
  601 AFKDILQGAR LDFGQLTFSS SLGLITLLKK VCNSPGLVGS DPYYKSHIKD TQSQDSYSRS 660
  661 LNSGKLKVLM TLLEGIRKGT KEKVVVVSNY TQTLDIIENL MNMAGMSHCR LDGSIPAKQR 720
  721 DSIVTSFNRN PAIFGFLLSA KSGGVGLNLV GRSRLILFDN DWNPSVDLQA MSRIHRDGQK 780
  781 KPCFIYRLVT TGCIDEKILQ RQLMKNSLSQ KFLGDSEMRN KESSNDDLFN KEDLKDLFSV 840
  841 HTDTKSNTHD LICSCDGLGE EIEYPETNQQ QNTVELRKRS TTTWTSALDL QKKMNEAATN 900
  901 DDAKKSQYIR QCLVHYKHID PARQDELFDE VITDSFTELK DSITFAFVKP GEICLREQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..269] MSA 3.282997 View MSA. No confident structure predictions are available.
    2 View Details [270..338] deduced N/A No confident structure predictions are available.
    3 View Details [339..524] ORFEUS 11.96 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    4 View Details [525..656] PSI-BLAST 19.39794 Putative DEAD box RNA helicase
    5 View Details [657..958] PSI-BLAST 5.69897 Nucleotide excision repair enzyme UvrB


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle