| Protein: | EDS1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 919 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EDS1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..919] | [1..919] |
|
|
3.0E-45 | [35..390] | [56..488] |
|
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3.0E-44 | [3..335] | [61..428] |
|
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6.0E-44 | [5..350] | [723..1075] |
|
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9.0E-39 | [5..400] | [930..1308] |
|
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1.0E-37 | [1..321] | [1..312] |
|
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4.0E-36 | [14..321] | [7..312] |
|
Region A: Residues: [1-134] |
1 11 21 31 41 51
| | | | | |
1 MSHHVPNLYG TPIRDPHERK RNSASMGEVN QSVSSRNCER GSEKGTKQRK KASHACDQCR 60
61 RKRIKCRFDK HTGVCQGCLE VGEKCQFIRV PLKRGPAKKR GSVVSIEKFS SDNDPLQYRP 120
121 RTHSYPMNSG NNYL
|
| Detection Method: |  |
| Confidence: | 8.69897 |
| Match: | 1hwtC_ |
| Description: | Hap1 (Cyp1); HAP1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 0.625108569999163 | bayes_pls_golite062009 |
| nucleic acid binding | 0.297563906361978 | bayes_pls_golite062009 |
| DNA binding | 0.187456195219132 | bayes_pls_golite062009 |
| transcription regulator activity | 0.0382143741325586 | bayes_pls_golite062009 |
|
Region A: Residues: [135-221] |
1 11 21 31 41 51
| | | | | |
1 PSLARNSSFP SISSLFVPSI TAQSQQFVKV PYDDIKRRSS LAILGSDSSI STEFGGNYRL 60
61 DENLNVRQEG KDIVAKGMIT PVEEMGA
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.569 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.569 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.506 | N/A | N/A | d.31.1 | Cdc48 domain 2-like |
| View | Download | 0.506 | N/A | N/A | d.31.1 | Cdc48 domain 2-like |
| View | Download | 0.413 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.384 | N/A | N/A | d.31.1 | Cdc48 domain 2-like |
| View | Download | 0.352 | N/A | N/A | b.114.1 | N-utilization substance G protein NusG, insert domain |
| View | Download | 0.352 | N/A | N/A | b.114.1 | N-utilization substance G protein NusG, insert domain |
| View | Download | 0.296 | N/A | N/A | b.33.1 | ISP domain |
| View | Download | 0.281 | N/A | N/A | b.84.1 | Single hybrid motif |
| View | Download | 0.260 | N/A | N/A | d.15.4 | 2Fe-2S ferredoxin-like |
| View | Download | 0.225 | N/A | N/A | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.218 | N/A | N/A | d.93.1 | SH2 domain |
|
Region A: Residues: [222-393] |
1 11 21 31 41 51
| | | | | |
1 CSSNVRRQGS QSLPIQEQRA SPYINPFISG RSRLSSLSYT SEATTSEGNT QGKNQCMLTP 60
61 NSVRSIEKER LNSLTAGFPN KKLGTDGRSD KWDKNSTWKP VYRSSNPSHP STEKNVSLNQ 120
121 EASAKPLMLG TYRQFDATSF YKVLGIYYNF FHINFPVIPI NKSKFTDMLD PE
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [394-447] |
1 11 21 31 41 51
| | | | | |
1 KPNVIDEIRQ INNEIIQCFK TALEVLVFCK IKQRRSSKST KSWSRDSLCD FQKG
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.537 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.506 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.480 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.464 | a.179.1 | Replisome organizer (g39p helicase loader/inhibitor protein) |
| View | Download | 0.421 | a.4.1 | Homeodomain-like |
| View | Download | 0.402 | a.2.9 | C-terminal UvrC-binding domain of UvrB |
| View | Download | 0.373 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.303 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.288 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.278 | a.4.1 | Homeodomain-like |
| View | Download | 0.272 | a.55.1 | IHF-like DNA-binding proteins |
| View | Download | 0.268 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.250 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.236 | d.47.1 | Ribosomal protein L11, N-terminal domain |
| View | Download | 0.233 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.218 | a.74.1 | Cyclin-like |
| View | Download | 0.209 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.204 | a.126.1 | Serum albumin-like |
|
Region A: Residues: [448-807] |
1 11 21 31 41 51
| | | | | |
1 LYYIQNFNKC IADCFQSLIT IKPVLKQNSS VIPSRIKFIY FSTIIVLNFI LILAGEESSL 60
61 LLGPSVGVFN EFQAHKLFLP FQNTSPMLLL NSNEESGDEI LDYAVLFKRL YILLNILDTL 120
121 QSFRLGQPKL INLNFGSAIE TYFSDKTGHN QVVEKAPVAL DNILRNLKLG EFITYFVLNR 180
181 KSLQVNVPHH LLFTNQTDYG EFAVEKGEHD NIAGKFETLL KKKEILIRKL LNIEQKNDHI 240
241 LENCCNSDAE MKNIGELVCS MITLVSGILD SITNMNAENS VDLDSKPLPN AYFAQDSEEE 300
301 LMSPTQSITS NLASEENTRC TTKDLMGTVS IFMLPMVEEC YNIISLIGPI PTTLISLYIR 360
361
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| Detection Method: | |
| Confidence: | 7.04 |
| Match: | 1b8fA |
| Description: | Histidine ammonia-lyase (HAL) |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [808-919] |
1 11 21 31 41 51
| | | | | |
1 NGNMAKGIND RIMTLSTALN ELVQITALFN TLEPFRKNAH DRAKRYYVSA TSSTGCYESV 60
61 MKSMYSGKCA ASNASNVAPS EEENKKILKK FADIGWKLMD DSELGCCCCF FN
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.597 | a.7.7 | BAG domain |
| View | Download | 0.597 | a.7.7 | BAG domain |
| View | Download | 0.431 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.431 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.336 | a.7.1 | Spectrin repeat |
| View | Download | 0.336 | a.7.1 | Spectrin repeat |
| View | Download | 0.329 | d.58.49 | YajQ-like |
| View | Download | 0.329 | d.58.49 | YajQ-like |
| View | Download | 0.297 | a.74.1 | Cyclin-like |
| View | Download | 0.297 | a.74.1 | Cyclin-like |
| View | Download | 0.285 | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.253 | c.47.1 | Thioredoxin-like |
| View | Download | 0.252 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.251 | d.58.34 | Formiminotransferase domain of formiminotransferase-cyclodeaminase. |
| View | Download | 0.242 | c.45.1 | (Phosphotyrosine protein) phosphatases II |
| View | Download | 0.237 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.226 | d.227.1 | OsmC-like |
| View | Download | 0.221 | a.1.1 | Globin-like |
| View | Download | 0.209 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.207 | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.207 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.204 | a.118.1 | ARM repeat |
