| Protein: | ALK2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 676 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALK2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..676] | [1..676] |
|
|
0.0 | [9..664] | [95..772] |
|
|
0.0 | [9..664] | [13..669] |
|
|
0.0 | [9..664] | [12..689] |
|
|
0.0 | [51..671] | [41..686] |
|
|
0.0 | [25..661] | [141..796] |
|
|
0.0 | [89..661] | [8..593] |
|
Region A: Residues: [1-368] |
1 11 21 31 41 51
| | | | | |
1 MNFDAVADQQ MTDRRYFALE VAESDDADSS LNSSSMGSPA VDVGRKVYKI TSHKGSAEDE 60
61 SQSFFTSSDS PTSKTRPVGK TIENDDYYGK RSSTGSSLKQ LFNKININDT AHSSNKENVS 120
121 QSVLSENKLL SPSKRLSKQG LTKVTNSKFR TPLRPISNQS TLSRDEPVKD FRSLKFRSGS 180
181 DFKCWGDEKT SSHVHSSSVN SVNSFTSTTS SSKWKFWKND NLLSRSLSSR SVNDQDPNFV 240
241 QPKPTNSLQK KSSISSFHNS IFGGGKHTEK KRNSGFIMPD HQSTKELNHK HSSSNLSFRS 300
301 LKHKTSHSSL NKLKVRRKGN TQELNHPIKK TCQISLPVPD QVSKDKIQLK LKNSTSLASL 360
361 SSEVTPIN
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [369-489] |
1 11 21 31 41 51
| | | | | |
1 TLDYNDSILQ QILQLCDVKY ILHDLREAQS LGLFTLNTRS VQLSHNFWQT YHSDMQTSLI 60
61 CKKVCLGALS DLTTSNLISL HELKSLRLIQ GTSGVANLLQ AYVVPSNQCE NDQNLILYLF 120
121 F
|
| Detection Method: | |
| Confidence: | 101.0 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [490-561] |
1 11 21 31 41 51
| | | | | |
1 KYQGTPLSRC SNIDYSQALS IFWQCSSILY VAESKFQLEH RNLTLDHILI DSKGNVTLID 60
61 MKCCRFLNID NN
|
| Detection Method: | |
| Confidence: | 101.0 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 5.08693983533348 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 4.80278598786839 | bayes_pls_golite062009 |
| kinase activity | 4.59756610116144 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.25355168820731 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.23864440079487 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| ATP binding | 1.87003701072722 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.82650528610717 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.79644024762454 | bayes_pls_golite062009 |
| binding | 1.69939147712641 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.56978145564551 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.56956819263374 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.54471996792105 | bayes_pls_golite062009 |
| nucleotide binding | 1.53595022832543 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| protein binding | 1.17747188575743 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.17063753242103 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.05410128646972 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.98751004123886 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.439470338563384 | bayes_pls_golite062009 |
| magnesium ion binding | 0.0936583701619971 | bayes_pls_golite062009 |
|
Region A: Residues: [562-612] |
1 11 21 31 41 51
| | | | | |
1 KASYTRLDHH YFFQGRGTLQ FEIYELMRSM LPQPISWATF EPRTNLLWLY H
|
| Detection Method: | |
| Confidence: | 101.0 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [613-676] |
1 11 21 31 41 51
| | | | | |
1 LSSSLLKMAK KAVVSGALNR EENILIELTH LLDPARKHSK TIFKKELVIR TCGDLLSLKG 60
61 EIMQ
|
| Detection Method: | |
| Confidence: | 101.0 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
| Matching Structure (courtesy of the PDB): |
|
