| Protein: | CDC24 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 854 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC24.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..854] | [1..854] |
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|
0.0 | [119..854] | [1..736] |
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0.0 | [23..851] | [14..757] |
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8.0E-94 | [155..839] | [104..846] |
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2.0E-88 | [67..727] | [924..1585] |
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5.0E-86 | [151..730] | [355..920] |
|
Region A: Residues: [1-133] |
1 11 21 31 41 51
| | | | | |
1 MAIQTRFASG TSLSDLKPKP SATSISIPMQ NVMNKPVTEQ DSLFHICANI RKRLEVLPQL 60
61 KPFLQLAYQS SEVLSERQSL LLSQKQHQEL LKSNGANRDS SDLAPTLRSS SISTATSLMS 120
121 MEGISYTNSN PSA
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.431 | 0.092 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.118.8 | TPR-like |
| View | Download | 0.421 | 0.019 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.571 | 0.009 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.490 | 0.007 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.17.1 | p8-MTCP1 |
| View | Download | 0.571 | N/A | N/A | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.521 | N/A | N/A | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.521 | N/A | N/A | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.490 | N/A | N/A | a.17.1 | p8-MTCP1 |
| View | Download | 0.431 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.421 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.402 | N/A | N/A | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.394 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.392 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.372 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.359 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.332 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.306 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.305 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.303 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.300 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.296 | N/A | N/A | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.276 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.266 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.251 | N/A | N/A | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.242 | N/A | N/A | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.233 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.232 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.232 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.225 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.223 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.220 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.220 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.217 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.214 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.208 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.208 | N/A | N/A | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.202 | N/A | N/A | f.1.2 | Diphtheria toxin, middle domain |
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Region A: Residues: [134-253] |
1 11 21 31 41 51
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1 TPNMEDTLLT FSMGILPITM DCDPVTQLSQ LFQQGAPLCI LFNSVKPQFK LPVIASDDLK 60
61 VCKKSIYDFI LGCKKHFAFN DEELFTISDV FANSTSQLVK VLEVVETLMN SSPTIFPSKS 120
121
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| Detection Method: | |
| Confidence: | 11.69897 |
| Match: | 1h67A_ |
| Description: | Calponin |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [254-458] |
1 11 21 31 41 51
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1 KTQQIMNAEN QHRHQPQQSS KKHNEYVKII KEFVATERKY VHDLEILDKY RQQLLDSNLI 60
61 TSEELYMLFP NLGDAIDFQR RFLISLEINA LVEPSKQRIG ALFMHSKHFF KLYEPWSIGQ 120
121 NAAIEFLSST LHKMRVDESQ RFIINNKLEL QSFLYKPVQR LCRYPLLVKE LLAESSDDNN 180
181 TKELEAALDI SKNIARSINE NQRRT
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| Detection Method: | |
| Confidence: | 202.457575 |
| Match: | 1foeA_ |
| Description: | GEF of TIAM1 (T-Lymphoma invasion and metastasis indusing protein 1) |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [459-642] |
1 11 21 31 41 51
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1 ENHQVVKKLY GRVVNWKGYR ISKFGELLYF DKVFISTTNS SSEPEREFEV YLFEKIIILF 60
61 SEVVTKKSAS SLILKKKSST SASISASNIT DNNGSPHHSY HKRHSNSSSS NNIHLSSSSA 120
121 AAIIHSSTNS SDNNSNNSSS SSLFKLSANE PKLDLRGRIM IMNLNQIIPQ NNRSLNITWE 180
181 SIKE
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| Detection Method: | |
| Confidence: | 202.457575 |
| Match: | 1foeA_ |
| Description: | GEF of TIAM1 (T-Lymphoma invasion and metastasis indusing protein 1) |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [643-754] |
1 11 21 31 41 51
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1 QGNFLLKFKN EETRDNWSSC LQQLIHDLKN EQFKARHHSS TSTTSSTAKS SSMMSPTTTM 60
61 NTPNHHNSRQ THDSMASFSS SHMKRVSDVL PKRRTTSSSF ESEIKSISEN FK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.555 | 0.519 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.1.1 | Globin-like |
| View | Download | 0.758 | 0.262 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.26.1 | 4-helical cytokines |
| View | Download | 0.422 | 0.240 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.1.1 | Globin-like |
| View | Download | 0.382 | 0.034 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | d.80.1 | Tautomerase/MIF |
| View | Download | 0.423 | 0.028 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | d.110.4 | SNARE-like |
| View | Download | 0.371 | 0.009 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.467 | 0.006 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.500 | 0.004 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.411 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.371 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.354 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.347 | N/A | N/A | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.324 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.314 | N/A | N/A | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.306 | N/A | N/A | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.302 | N/A | N/A | d.189.1 | PX domain |
| View | Download | 0.302 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.302 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.299 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.290 | N/A | N/A | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.283 | N/A | N/A | a.134.1 | Fungal elicitin |
| View | Download | 0.277 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.269 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.268 | N/A | N/A | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.267 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.266 | N/A | N/A | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.259 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.255 | N/A | N/A | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.254 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.251 | N/A | N/A | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.248 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.247 | N/A | N/A | d.52.2 | GMP synthetase C-terminal dimerisation domain |
| View | Download | 0.242 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.239 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.238 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.226 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.223 | N/A | N/A | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.222 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.220 | N/A | N/A | d.58.43 | Mechanosensitive channel protein MscS (YggB), C-terminal domain |
| View | Download | 0.220 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.218 | N/A | N/A | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.216 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.215 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.214 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.213 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.210 | N/A | N/A | a.112.1 | Description not found. |
| View | Download | 0.208 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.205 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.204 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| Term | Confidence | Notes |
| binding | 2.24212855645397 | bayes_pls_golite062009 |
| protein binding | 1.04550817342273 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.993282922991536 | bayes_pls_golite062009 |
| kinase activity | 0.682664093464385 | bayes_pls_golite062009 |
| signal transducer activity | 0.639296022362811 | bayes_pls_golite062009 |
| molecular transducer activity | 0.639296022362811 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.459633124432679 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.457933659119243 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.390993828682912 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.217422685675578 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.0693380673720717 | bayes_pls_golite062009 |
| protein kinase activity | 0.0278354564906339 | bayes_pls_golite062009 |
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Region A: Residues: [755-854] |
1 11 21 31 41 51
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1 NSIPESSILF RISYNNNSNN TSSSEIFTLL VEKVWNFDDL IMAINSKISN THNNNISPIT 60
61 KIKYQDEDGD FVVLGSDEDW NVAKEMLAEN NEKFLNIRLY
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
