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View Structure Prediction Details

Protein: rdx-PE
Organism: Drosophila melanogaster
Length: 829 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rdx-PE.

Description E-value Query
Range
Subject
Range
gi|109465202 - gi|109465202|ref|XP_227869.2| PREDICTED: similar to TD and POZ domain containing 2 [Rattus norvegicu...
475.0 [0..435] [828..85]

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Predicted Domain #1
Region A:
Residues: [1-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFEPYVKIKK KRSVNEIYEN ENLEQQQHHL QQQQQQPATS DNCCCENGEP QNAPEVATAT  60
   61 VAATSVAATS AAATVATGAA ASSSSSGNCS RLQQLISTPP VLLRRSSLQQ QQHQQQQHHP 120
  121 HTPAATATPP QQQQQQQAAP SVLQQHLGHL NYESGATAAA AATAAAAAAT VATSRSGSAT 180
  181 LAQHLATPSN ILQAAFGSSN LQHILTRSAP SPSSSAISSN NCSSACAGNT HYNGGNSNSG 240
  241 SSSSNSNHHS NSIIASRLFG AASSSSSSSS SSASASSSSV AASSSSSSHH LHSHHSALTN 300
  301 SITNRINQSI RRHLNQQQHH HPLSASSSSA SASPSASTSS SSSYQQSSVQ QQHYNCAHPA 360
  361 QQQQHHHHHH SSSSSSSSSS SSSHHHHNSS SSSNSNNQQQ PQQSPLCLVL LVKCPNSKEF 420
  421 CNAAANFCDK RLPVNECQAS QTARVTSNLH ASSSTMAVSR VPSPPL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.045757
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [467-629]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEVNTPVAEN WCYTQVKVVK FSYMWTINNF SFCREEMGEV LKSSTFSAGA NDKLKWCLRV  60
   61 NPKGLDEESK DYLSLYLLLV SCNKSEVRAK FKFSILNAKR EETKAMESQR AYRFVQGKDW 120
  121 GFKKFIRRDF LLDEANGLLP EDKLTIFCEV SVVADSVNIS GQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.154902
Match: 2cr2A
Description: Solution structure of N-terminal domain of speckle-type POZ protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 3.89053628409867 bayes_pls_golite062009
small conjugating protein ligase activity 3.68249288112226 bayes_pls_golite062009
acid-amino acid ligase activity 2.77614213354896 bayes_pls_golite062009
binding 2.72457822303946 bayes_pls_golite062009
protein binding 1.74340583625887 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 1.37597575764906 bayes_pls_golite062009
transcription regulator activity 1.31204855886285 bayes_pls_golite062009
nucleic acid binding 1.07240204386411 bayes_pls_golite062009
DNA binding 0.996677220619186 bayes_pls_golite062009
catalytic activity 0.00622013180681097 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [630-752]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIVQFKVPEC KLSEDLGNLF DNEKFSDVTL SVGGREFQAH KAILAARSDV FAAMFEHEME  60
   61 ERKLNRVAIT DVDHEVLKEM LRFIYTGKAP NLEKMADDLL AAADKYALEK LKVMCEEALC 120
  121 VNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 2nn2A
Description: No description for 2nn2A was found.

Predicted Domain #4
Region A:
Residues: [753-829]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVETAAETLI LADLHSADQL KAQTIDFINT HATDVMETSG WQNMITTHSH LIAEAFRALA  60
   61 TQQIPPIGPP RKRVKMS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 2eqxA
Description: No description for 2eqxA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle