YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|77629846, gi\|...
Organism:	Yersinia pseudotuberculosis IP 31758
Length:	519 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|77629846, gi|....

Description	E-value	Query Range	Subject Range
gi\|167051313, gi... - gi\|167398809\|ref\|ZP_02304333.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. UG05-0454], ... gi\|108780181, gi... - gi\|108808268\|ref\|YP_652184.1\| exopolyphosphatase [Yersinia pestis Antiqua], gi\|108780181\|gb\|ABG14239...	0.0	[1..519]	[1..519]
gi\|162352033, gi... - gi\|77636354\|ref\|ZP_00798429.1\| COG0248: Exopolyphosphatase [Yersinia pestis Angola], gi\|162419218\|re...	0.0	[1..519]	[1..519]
gi\|187731393, gi... - gi\|75178107\|ref\|ZP_00698166.1\| COG0248: Exopolyphosphatase [Shigella boydii BS512], gi\|187731393\|ref... gi\|82544949, gi\|... - gi\|82544949\|ref\|YP_408896.1\| exopolyphosphatase [Shigella boydii Sb227], gi\|81246360\|gb\|ABB67068.1\| ...	0.0	[1..513]	[1..512]
gi\|213864750 - gi\|213864750\|ref\|ZP_03386869.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|213647473 - gi\|213647473\|ref\|ZP_03377526.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|224582963, gi... - gi\|224582963\|ref\|YP_002636761.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par... gi\|214002891 - gi\|214002891\|ref\|ZP_03413626.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|194450339, gi... - gi\|194450339\|ref\|YP_002046566.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Hei... gi\|168466751, gi... - gi\|195630753\|gb\|EDX49345.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Newport ... gi\|213160884 - gi\|213160884\|ref\|ZP_03346594.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|199604572, gi... - gi\|200387474\|ref\|ZP_03214086.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Virc... gi\|161362107, gi... - gi\|161612743\|ref\|YP_001586708.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par... PPX_SALTI - Exopolyphosphatase OS=Salmonella typhi GN=ppx PE=3 SV=2 PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium GN=ppx PE=3 SV=2 PPX_SALTI - Exopolyphosphatase OS=Salmonella typhi GN=ppx PE=3 SV=2 gi\|238913641 - gi\|238913641\|ref\|ZP_04657478.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Tenn... gi\|29140883, gi\|... - gi\|29140883\|ref\|NP_804225.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typhi s... gi\|16761420 - gi\|16761420\|ref\|NP_457037.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typhi s... lcl\|NC_016856.1_... - [gene=ppx] [protein=exopolyphosphatase] [protein_id=YP_005238595.1] [location=2668560..2670101] PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium GN=ppx PE=3 SV=2 PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=ppx PE=3 SV=2	0.0	[1..513]	[1..512]
gi\|56126872, gi\|... - gi\|56412615\|ref\|YP_149690.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Paratyp... gi\|197361550, gi... - gi\|197361550\|ref\|YP_002141186.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par...	0.0	[1..513]	[1..512]
gi\|82777881, gi\|... - gi\|82777881\|ref\|YP_404230.1\| exopolyphosphatase [Shigella dysenteriae Sd197], gi\|81242029\|gb\|ABB6273...	0.0	[1..513]	[1..512]
gi\|83570721, gi\|... - gi\|83570721\|ref\|ZP_00922164.1\| COG0248: Exopolyphosphatase [Shigella dysenteriae 1012], gi\|194432122...	0.0	[1..513]	[1..512]
gi\|24113830, gi\|... - gi\|24113830\|ref\|NP_708340.1\| exopolyphosphatase [Shigella flexneri 2a str. 301], gi\|24052920\|gb\|AAN4... gi\|30042131, gi\|... - gi\|30063876\|ref\|NP_838047.1\| exopolyphosphatase [Shigella flexneri 2a str. 2457T], gi\|30042131\|gb\|AA...	0.0	[1..513]	[1..512]
gi\|15832618, gi\|... - gi\|15832618\|ref\|NP_311391.1\| exopolyphosphatase [Escherichia coli O157:H7 str. Sakai], gi\|13362834\|d... gi\|89109308, gi\|... - gi\|89109308\|ref\|AP_003088.1\| exopolyphosphatase [Escherichia coli str. K-12 substr. W3110], gi\|18055... gi\|91211823, gi\|... - gi\|91211823\|ref\|YP_541809.1\| exopolyphosphatase [Escherichia coli UTI89], gi\|91073397\|gb\|ABE08278.1\|... PPX_ECOLI - Exopolyphosphatase (EC 3.6.1.11) (ExopolyPase) (Metaphosphatase) - Escherichia coli PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ppx PE=3 SV=2 gi\|188017022, gi... - gi\|188017022\|gb\|EDU55144.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4113], gi\|168748440\|... PPX_ECO57 - Exopolyphosphatase OS=Escherichia coli O157:H7 GN=ppx PE=1 SV=2 gi\|168756273, gi... - gi\|189356554\|gb\|EDU74973.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4401], gi\|168756273\|... EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos... gi\|168773585, gi... - gi\|187770642\|gb\|EDU34486.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4196], gi\|168773585\|... gi\|12516890, gi\|... - gi\|15803025\|ref\|NP_289055.1\| exopolyphosphatase [Escherichia coli O157:H7 EDL933], gi\|12516890\|gb\|AA... gi\|189003181, gi... - gi\|189003181\|gb\|EDU72167.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4076], gi\|168778467\|... gi\|189372364, gi... - gi\|189372364\|gb\|EDU90780.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC869], gi\|168787847\|r... gi\|209398375, gi... - gi\|209398375\|ref\|YP_002271971.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4115], gi\|20915... gi\|209913238, gi... - gi\|209919979\|ref\|YP_002294063.1\| exopolyphosphatase [Escherichia coli SE11], gi\|209913238\|dbj\|BAG783... gi\|217319566, gi... - gi\|217327199\|ref\|ZP_03443282.1\| exopolyphosphatase [Escherichia coli O157:H7 str. TW14588], gi\|21731... EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos... gi\|218559426, gi... - gi\|218559426\|ref\|YP_002392339.1\| exopolyphosphatase [Escherichia coli S88], gi\|218366195\|emb\|CAR0394... gi\|218696129, gi... - gi\|218696129\|ref\|YP_002403796.1\| exopolyphosphatase [Escherichia coli 55989], gi\|218352861\|emb\|CAU98... gi\|254794447, gi... - gi\|254794447\|ref\|YP_003079284.1\| exopolyphosphatase [Escherichia coli O157:H7 str. TW14359], gi\|2545... gi\|218706001, gi... - gi\|218706001\|ref\|YP_002413520.1\| exopolyphosphatase [Escherichia coli UMN026], gi\|218433098\|emb\|CAR1... gi\|253974377, gi... - gi\|254162476\|ref\|YP_003045584.1\| exopolyphosphatase [Escherichia coli B str. REL606], gi\|253974377\|g... gi\|253323650, gi... - gi\|254289237\|ref\|YP_003054985.1\| exopolyphosphatase [Escherichia coli BL21(DE3)], gi\|253978544\|gb\|AC... gi\|251785827, gi... - gi\|251785827\|ref\|YP_003000131.1\| hypothetical protein B21_02356 [Escherichia coli BL21], gi\|24237810... gi\|168798872, gi... - gi\|189378553\|gb\|EDU96969.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC508], gi\|168798872\|r... gi\|238861059, gi... - gi\|238901667\|ref\|YP_002927463.1\| exopolyphosphatase [Escherichia coli BW2952], gi\|238861059\|gb\|ACR63... gi\|169754142, gi... - gi\|170019214\|ref\|YP_001724168.1\| exopolyphosphatase [Escherichia coli ATCC 8739], gi\|169754142\|gb\|AC... gi\|226901374, gi... - gi\|237705008\|ref\|ZP_04535489.1\| exopolyphosphatase [Escherichia sp. 3_2_53FAA], gi\|226901374\|gb\|EEH8... gi\|74313028, gi\|... - gi\|74313028\|ref\|YP_311447.1\| exopolyphosphatase [Shigella sonnei Ss046], gi\|73856505\|gb\|AAZ89212.1\| ... gi\|169889947, gi... - gi\|170082112\|ref\|YP_001731432.1\| exopolyphosphatase [Escherichia coli str. K-12 substr. DH10B], gi\|1... gi\|227835882, gi... - gi\|227887532\|ref\|ZP_04005337.1\| exopolyphosphatase [Escherichia coli 83972], gi\|227835882\|gb\|EEJ4634... PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6 GN=ppx PE=3 SV=2 gi\|170682766, gi... - gi\|170682766\|ref\|YP_001744686.1\| exopolyphosphatase [Escherichia coli SMS-3-5], gi\|170520484\|gb\|ACB1... gi\|195936644 - gi\|195936644\|ref\|ZP_03082026.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4024] gi\|208728650, gi... - gi\|208808849\|ref\|ZP_03251186.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4206], gi\|208728... gi\|208814562, gi... - gi\|208814562\|ref\|ZP_03255891.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4045], gi\|208735... gi\|208739064, gi... - gi\|208818941\|ref\|ZP_03259261.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4042], gi\|208739... gi\|194423464, gi... - gi\|83586849\|ref\|ZP_00925480.1\| COG0248: Exopolyphosphatase [Escherichia coli 101-1], gi\|194437658\|re... gi\|193064767, gi... - gi\|75257309\|ref\|ZP_00728833.1\| COG0248: Exopolyphosphatase [Escherichia coli E22], gi\|193064767\|ref\|... gi\|188493752, gi... - gi\|75515843\|ref\|ZP_00737978.1\| COG0248: Exopolyphosphatase [Escherichia coli 53638], gi\|188493752\|re... gi\|157078836, gi... - gi\|75187254\|ref\|ZP_00700521.1\| COG0248: Exopolyphosphatase [Escherichia coli E24377A], gi\|157156806\|... gi\|75211469, gi\|... - gi\|75211469\|ref\|ZP_00711559.1\| COG0248: Exopolyphosphatase [Escherichia coli B171], gi\|194427254\|ref... gi\|117624686, gi... - gi\|117624686\|ref\|YP_853599.1\| exopolyphosphatase [Escherichia coli APEC O1], gi\|115513810\|gb\|ABJ0188...	0.0	[1..513]	[1..512]
gi\|75196510, gi\|... - gi\|75196510\|ref\|ZP_00706580.1\| COG0248: Exopolyphosphatase [Escherichia coli HS], gi\|157161963\|ref\|Y...	0.0	[1..513]	[1..512]

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Predicted Domain #1

Region A:
Residues: [1-519]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLTNNSTTK PQEIAAIDLG SNSFHMVIAR VVNGALQVLG RLKQRVHLAD GLDSNNMLSE  60
   61 EAIERGLACL ALFAERLQGF SPDNVCIVGT HTLRQAANAE TFLKRAAEVI PYPIEIISGQ 120
  121 EEARLIFMGV EHTQPEKGRK LVIDIGGGST EMVIGEDFEP LLVESRRMGC VSFAQQFFPG 180
  181 GEISKNNFRR ARLAAAQKLE NLAWQYRIQG WQYALGASGT IKATYEVLVE MGEKDGLITP 240
  241 ERLEMLVENV LQFKQFSALS LPGLSEDRQS VFVPGLAILC GVFDALAIKT LRLSDGALRE 300
  301 GVLYEMEGRF RHQDIRQRTA KSLADHYNID REQARRVLET TEQLYTQWLA QNTKLVQPQL 360
  361 EALLKWAAML HEVGLSINHS GMHRHSAYIL QNTNLPGFNQ EQQTLLATLV RMHRKAIKLD 420
  421 ELPRLNLFKK KYYLPLIQLL RLSTLLNNQR QSTTTPESLR LITDDSHWTL RFPHGYLTQN 480
  481 SLVQLDFERE QAYWDDVVGW KLVIEEEEPD EAAKVAPEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	159.0
Match:	1u6zA
Description:	Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	1.87760960987608	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.75615325783105	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.59605394946105	bayes_pls_golite062009
binding	1.25460196265758	bayes_pls_golite062009
polyphosphate kinase activity	1.21204737821821	bayes_pls_golite062009
protein binding	1.01732312833155	bayes_pls_golite062009
phosphoric diester hydrolase activity	0.924155015104714	bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity	0.641327801104871	bayes_pls_golite062009
transferase activity	0.569421514787167	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	0.532800957697682	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
adenyl nucleotide binding	0.232254847278069	bayes_pls_golite062009
ATP binding	0.20090931123533	bayes_pls_golite062009
adenyl ribonucleotide binding	0.164881755458122	bayes_pls_golite062009
protein kinase activity	0.0746500139691637	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: