YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|126195191, gi...
Organism:	Pseudomonas aeruginosa 2192
Length:	360 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|126195191, gi....

Description	E-value	Query Range	Subject Range
gi\|1314267 - gi\|1314267\|gb\|AAC45419.1\| 3-isopropylmalate dehydrogenase [Pseudomonas aeruginosa] gi\|1314267\|gb\|AA... - 3-isopropylmalate dehydrogenase [Pseudomonas aeruginosa]	0.0	[1..360]	[1..360]
gi\|49086956 - gi\|49086956\|gb\|AAT51399.1\| PA3118 [synthetic construct]	0.0	[1..360]	[1..360]
gi\|84320117, gi\|... - gi\|84320117\|ref\|ZP_00968502.1\| COG0473: Isocitrate/isopropylmalate dehydrogenase [Pseudomonas aerugi...	0.0	[1..360]	[1..360]
gi\|95109800 - gi\|95109800\|emb\|CAK14505.1\| 3-isopropylmalate dehydrogenase [Pseudomonas entomophila L48] gi\|104780813, gi... - gi\|95109800\|emb\|CAK14505.1\| 3-isopropylmalate dehydrogenase [Pseudomonas entomophila L48], gi\|104780...	0.0	[1..360]	[1..360]
gi\|152983912, gi... - gi\|94412522\|ref\|ZP_01292439.1\| hypothetical protein PaerP_01005695 [Pseudomonas aeruginosa PA7], gi\|...	0.0	[1..360]	[1..360]
LEU3_PSEF5 - 3-isopropylmalate dehydrogenase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) GN=leuB PE=3...	0.0	[1..360]	[1..360]
LEU3_PSEPF - 3-isopropylmalate dehydrogenase OS=Pseudomonas fluorescens (strain Pf0-1) GN=leuB PE=3 SV=1	0.0	[1..360]	[1..360]
gi\|82713613, gi\|... - gi\|82739313\|ref\|ZP_00902120.1\| 3-isopropylmalate dehydrogenase [Pseudomonas putida F1], gi\|82713613\|... tr\|I7B4Y4\|I7B4Y4... - 3-isopropylmalate dehydrogenase OS=Pseudomonas putida (strain DOT-T1E) GN=leuB PE=3 SV=1 LEU3_PSEPK - 3-isopropylmalate dehydrogenase OS=Pseudomonas putida (strain KT2440) GN=leuB PE=3 SV=1 tr\|E4RBI5\|E4RBI5... - 3-isopropylmalate dehydrogenase OS=Pseudomonas putida (strain BIRD-1) GN=leuB PE=3 SV=1	0.0	[1..360]	[1..360]
LEU3_AQUAE - 3-isopropylmalate dehydrogenase OS=Aquifex aeolicus (strain VF5) GN=leuB PE=3 SV=1 LEU3_AQUAE - 3-isopropylmalate dehydrogenase OS=Aquifex aeolicus GN=leuB PE=3 SV=1	0.0	[2..360]	[3..359]
LEU3_PSE14 - 3-isopropylmalate dehydrogenase OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) G...	0.0	[1..360]	[1..360]

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Predicted Domain #1

Region A:
Residues: [1-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKQILVLPG DGIGPEIMAE AVKVLELAND RFQLGFELAE DVIGGAAIDK HGVPLADQTL  60
   61 QRARQADAVL LGAVGGPKWD RIERDIRPER GLLKIRSQLG LFANLRPAIL YPQLAAASSL 120
  121 KPEVVAGLDI LIVRELTGGI YFGQPREQRV LENGERQAYD TLPYSESEIR RIARVGFDMA 180
  181 RVRNNRLCSV DKANVLASSQ LWREVVEEVA KDYPDVELSH MYVDNAAMQL VRAPKQFDVM 240
  241 VTDNMFGDIL SDEASMLTGS IGMLPSASLD ANNKGMYEPC HGSAPDIAGQ GIANPLATIL 300
  301 SVSMMLRYSF SQATAADAIE QAVSKVLDQG LRTGDIWSEG CRKVGTREMG DAVVAALKNL 360
  361

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Detection Method:	PSI-BLAST
Confidence:	121.0
Match:	1cnzA
Description:	3-isopropylmalate dehydrogenase, IPMDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
isocitrate dehydrogenase (NAD+) activity	5.9567768649084	bayes_pls_golite062009
isocitrate dehydrogenase activity	5.76817846591752	bayes_pls_golite062009
3-isopropylmalate dehydrogenase activity	4.43187390953534	bayes_pls_golite062009
isocitrate dehydrogenase (NADP+) activity	3.47645456015586	bayes_pls_golite062009
malate dehydrogenase activity	3.17013707624362	bayes_pls_golite062009
oxidoreductase activity	2.74237430402883	bayes_pls_golite062009
catalytic activity	2.71251959637136	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.46799258909805	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.38235863668553	bayes_pls_golite062009
binding	1.19820115767498	bayes_pls_golite062009
malic enzyme activity	0.483776792839856	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.466038297142601	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: