YRC Public Data Repository - Protein Structure Prediction

Protein:	RPE_ECOL6
Organism:	Escherichia coli O6
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPE_ECOL6.

Description	E-value	Query Range	Subject Range
gi\|170718563, gi... - gi\|53728308\|ref\|ZP_00348123.1\| COG0036: Pentose-5-phosphate-3-epimerase [Haemophilus somnus 2336], g... gi\|23467805, gi\|... - gi\|23467805\|ref\|ZP_00123383.1\| COG0036: Pentose-5-phosphate-3-epimerase [Haemophilus somnus 129PT], ...	229.0	[0..1]	[225..1]
gi\|12722019, gi\|... - gi\|15603484\|ref\|NP_246558.1\| ribulose-phosphate 3-epimerase [Pasteurella multocida subsp. multocida ...	229.0	[0..1]	[222..16]
gi\|59712895, gi\|... - gi\|59712895\|ref\|YP_205671.1\| ribulose-phosphate 3-epimerase [Vibrio fischeri ES114], gi\|59480996\|gb\|...	227.0	[0..1]	[224..1]
gi\|120326270, gi... - gi\|77953959\|ref\|ZP_00818361.1\| Ribulose-phosphate 3-epimerase [Marinobacter aquaeolei VT8], gi\|77867...	227.0	[0..1]	[224..1]
gi\|52308437, gi\|... - gi\|52426385\|ref\|YP_089522.1\| ribulose-phosphate 3-epimerase [Mannheimia succiniciproducens MBEL55E],...	226.0	[0..1]	[224..1]
gi\|78702071, gi\|... - gi\|78702071\|ref\|ZP_00866514.1\| Ribulose-phosphate 3-epimerase [Alkalilimnicola ehrlichei MLHE-1], gi...	225.0	[0..1]	[222..1]
gi\|86147333, gi\|... - gi\|86147333\|ref\|ZP_01065647.1\| ribulose-phosphate 3-epimerase [Vibrio sp. MED222], gi\|85834898\|gb\|EA...	225.0	[0..1]	[222..1]
gi\|68249166, gi\|... - gi\|68249166\|ref\|YP_248278.1\| ribulose-phosphate 3-epimerase [Haemophilus influenzae 86-028NP], gi\|68...	225.0	[0..1]	[223..11]
gi\|84376617, gi\|... - gi\|84390814\|ref\|ZP_00991506.1\| ribulose-phosphate 3-epimerase [Vibrio splendidus 12B01], gi\|84376617...	224.0	[0..1]	[222..1]
gi\|88949336, gi\|... - gi\|88949336\|ref\|ZP_01151954.1\| Ribulose-phosphate 3-epimerase [Halorhodospira halophila SL1], gi\|889...	223.0	[0..1]	[224..1]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQYLIAPSI LSADFARLGE DTAKALAAGA DVVHFDVMDN HYVPNLTIGP MVLKSLRNYG  60
   61 ITAPIDVHLM VKPVDRIVPD FAAAGASIIT FHPEASEHVD RTLQLIKENG CKAGLVFNPA 120
  121 TPLSYLDYVM DKLDVILLMS VNPGFGGQSF IPQTLDKLRE VRRRIDESGF DIRLEVDGGV 180
  181 KVNNIGEIAA AGADMFVAGS AIFDQPDYKK VIDEMRSELA KVSHE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.39794
Match:	1tqjA
Description:	Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribulose-phosphate 3-epimerase activity	3.28372503209224	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
intramolecular oxidoreductase activity	1.86158562896415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.36492964250879	bayes_pls_golite062009
isomerase activity	0.935800409577999	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.764608070506109	bayes_pls_golite062009
orotidine-5'-phosphate decarboxylase activity	0.758594564254247	bayes_pls_golite062009
binding	0.595171555788202	bayes_pls_golite062009
racemase and epimerase activity	0.288948763149344	bayes_pls_golite062009
carboxy-lyase activity	0.1100847613283	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: