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View Structure Prediction Details

Protein: daf-16
Organism: Caenorhabditis elegans
Length: 487 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for daf-16.

Description E-value Query
Range
Subject
Range
daf-16 - status:Partially_confirmed
216.0 [0..13] [487..94]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFSTDFDDD FFNLDLHQQE RSASFGGVTQ YSQQFLREKC SFSPYFHTSL ETVDSGRTSL  60
   61 YGSNEQCGQL GGASSNGSTA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [81-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHTPDGSNS HQTSFPSDFR MSESPDDTVS GKKTTTRRNA WGNMSYAELI TTAIMASPEK  60
   61 RLTLAQVYEW MVQNVPYFRD KGDSNSSAGW KNSIRHNLSL HSRFMRIQNE GAGKSSWWVI 120
  121 NPDAKPGRNP RRTRERSNTI ETTTKAQLEK SR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.045757
Match: 1e17A
Description: Afx (Foxo4)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [233-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGAKKRIKER ALMGSLHSTL NGNSIAGSIQ TISHDLYDDD SMQGAFDNVP SSFRPRTQSN  60
   61 LSIPGSSSRV SPAIGSDIYD DLEFPSWVGE SVPAIPSDIV DRTDQMRIDA TTHIGGVQIK 120
  121 QESKPIKTEP IAPPPSYHEL NSVRGSCAQN PLLRNPIVPS TNFKPMPLPG AYGNYQNGGI 180
  181 TPINWLSTSN SSPLPGIQSC GIVAAQHTVA SSSALPIDLE NLTLPDQPLM DTMDVDALIR 240
  241 HELSQAGGQH IHFDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle