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View Structure Prediction Details

Protein: nhr-110
Organism: Caenorhabditis elegans
Length: 326 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-110.

Description E-value Query
Range
Subject
Range
nhr-130 - zinc finger protein status:Partially_confirmed UniProt:O16963 protein_id:AAG24183.1
219.0 [0..1] [325..103]

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Predicted Domain #1
Region A:
Residues: [1-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPENIQYDR DKFESILKSS KNNRHLQIPN TVESQLCISP LVSFSNRREK SSKCIDISQI  60
   61 VKKAVAKLLN PAMIRNIDST SNLEQLTSGF KNLQSGQKEN IPKIDHITLA HQTQHFNSSM 120
  121 CSAAVWLGYS DRFKTYSDMQ KIKVLQAIWC IWGRLEGIVM TAKMRIIGKC EKEQFFLTSD 180
  181 TLIVYDNFSS DLDYCSTYPF EEMKYFFIPR EMFHEDVISE LVKVQPDDVE TTYLMSVVCL 240
  241 QLTGKRYGGL IQEEMEQFQD ILSNDLHEYY INNKMPKYLL RIKQLMRVKE MFLRNLNIRM 300
  301 EKYKIAGVFN VFNRPISNLE FFTVPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.09691
Match: 1lbdA
Description: LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.07679393058916 bayes_pls_golite062009
protein binding 1.4692467191721 bayes_pls_golite062009
transcription regulator activity 1.38569381220638 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.33970394025402 bayes_pls_golite062009
receptor activity 1.27827487658808 bayes_pls_golite062009
DNA binding 1.07558579137079 bayes_pls_golite062009
nucleic acid binding 0.843756208408716 bayes_pls_golite062009
signal transducer activity 0.729591594314124 bayes_pls_golite062009
molecular transducer activity 0.729591594314124 bayes_pls_golite062009
transcription factor activity 0.523911554416 bayes_pls_golite062009
sequence-specific DNA binding 0.14253203697325 bayes_pls_golite062009
transcription activator activity 0.0654022419611198 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle