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Protein Overview: nhr-130

General Information:
Name(s) found: nhr-130 / CE18167 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00003720 locus:nhr-130 Nuclear hormone receptor family member nhr-130 status:Partially_confirmed UniProt:O16963 protein_id:CCD73123.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 440 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIATSSTSP SIFYTPSISP MEEDMNCQEL VVNLYTCQVC ALPAHGNHFG AISCRACAAF  60
   61 FRRACTGTKT TYKCKKQNNC DIWENGRYKC KKCRLDRCNE VGMDPGRFQF DRDLISATEK 120
  121 YPNSKNFRRT FGMSRLPETI EHFLGRPHFI IFLERHIYSH SEKNFVDLQH LIAKASKLLE 180
  181 LGSEKPLIAR NNLEKLALGL NLVRDQPAGS HDVQLVTKLG KDEALTFWET DFLTVAKWLT 240
  241 YFDDFQLLPH NQQILLLKSV WHVWNRLEKL ALTATSRRQN VCEQKQLMLT YNSVCNPKTI 300
  301 ELDYSWFTKY PKEQLCFFFD EMEDYMLTSA LDPLTSLEPT DIELTYMLCQ LCFHYAGKRY 360
  361 GGEILEVTEK FQENLADNLH DYYVNELNMP RYCGRLNQML KINNLIQQDI WEKRAKHELA 420
  421 KVFDIFCIEF SHPEMFEDTG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] PSI-BLAST 21.30103 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    2 View Details [104..440] PSI-BLAST 29.154902 hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle