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View Structure Prediction Details

Protein: nhr-130
Organism: Caenorhabditis elegans
Length: 440 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-130.

Description E-value Query
Range
Subject
Range
gi|73967652 - gi|73967652|ref|XP_548399.2| PREDICTED: similar to Retinoic acid receptor RXR-alpha (Retinoid X rece...
279.0 [0..3] [437..30]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIATSSTSP SIFYTPSISP MEEDMNCQEL VVNLYTCQVC ALPAHGNHFG AISCRACAAF  60
   61 FRRACTGTKT TYKCKKQNNC DIWENGRYKC KKCRLDRCNE VGM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.30103
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [104-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPGRFQFDRD LISATEKYPN SKNFRRTFGM SRLPETIEHF LGRPHFIIFL ERHIYSHSEK  60
   61 NFVDLQHLIA KASKLLELGS EKPLIARNNL EKLALGLNLV RDQPAGSHDV QLVTKLGKDE 120
  121 ALTFWETDFL TVAKWLTYFD DFQLLPHNQQ ILLLKSVWHV WNRLEKLALT ATSRRQNVCE 180
  181 QKQLMLTYNS VCNPKTIELD YSWFTKYPKE QLCFFFDEME DYMLTSALDP LTSLEPTDIE 240
  241 LTYMLCQLCF HYAGKRYGGE ILEVTEKFQE NLADNLHDYY VNELNMPRYC GRLNQMLKIN 300
  301 NLIQQDIWEK RAKHELAKVF DIFCIEFSHP EMFEDTG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.154902
Match: 1z5xE
Description: hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle