YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|54035442
Organism:	Xenopus laevis
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|54035442.

Description	E-value	Query Range	Subject Range
gi\|60475480, gi\|... - gi\|66828131\|ref\|XP_647420.1\| hypothetical protein DDBDRAFT_0189650 [Dictyostelium discoideum AX4], g... gi\|60475480 - gi\|60475480\|gb\|EAL73415.1\| hypothetical protein DDB0189650 [Dictyostelium discoideum]	186.0	[0..3]	[225..789]
gi\|237823654, gi... - gi\|71273690\|emb\|CAG77578.1\| Na, K-ATPase alpha subunit [Squalus acanthias], gi\|237823654\|pdb\|2ZXE\|A ...	185.0	[0..4]	[225..505]
AT1A_TETCF - Sodium/potassium-transporting ATPase subunit alpha OS=Tetronarce californica PE=1 SV=1	183.0	[0..4]	[225..499]
gi\|89268073, gi\|... - gi\|89268073\|emb\|CAJ83211.1\| ATPase, Na+/K+ transporting, alpha 1 polypeptide [Xenopus tropicalis], g...	183.0	[0..4]	[225..500]
gi\|148229987, gi... - gi\|29294657\|gb\|AAH49006.1\| MGC53886 protein [Xenopus laevis], gi\|28277361\|gb\|AAH44670.1\| MGC53886 pr...	183.0	[0..4]	[225..500]
gi\|68391358 - gi\|68391358\|ref\|XP_701983.1\| PREDICTED: hypothetical protein XP_696891 [Danio rerio]	182.0	[0..4]	[225..436]
gi\|19918508, gi\|... - gi\|20093165\|ref\|NP_619240.1\| sodium/potassium-transporting ATPase, alpha subunit [Methanosarcina ace...	182.0	[0..3]	[225..468]
AT1A_ARTSF - Sodium/potassium-transporting ATPase subunit alpha-A OS=Artemia franciscana PE=2 SV=1	182.0	[0..3]	[225..474]
gi\|73948281 - gi\|73948281\|ref\|XP_855286.1\| PREDICTED: similar to Na+/K+ -ATPase alpha 3 subunit [Canis familiaris]	182.0	[0..4]	[225..547]
AT1A3_CHICK - Sodium/potassium-transporting ATPase subunit alpha-3 OS=Gallus gallus GN=ATP1A3 PE=2 SV=1	182.0	[0..4]	[225..487]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSHSELRKL FCSADAVCFD VDSTVIREEG IDELAKFCGV EAAVSEMTRR AMGGALPFKD  60
   61 ALTQRLALIQ PSRDQVQRLL AEHPPHLTPG IRELVSRLQE RNVQVFLISG GFRSIVEHVA 120
  121 AKLNIPTTNV FANRLKFYFN GEYAGFDEMQ PTAESGGKGK VIRFLKEKFH FKKIIMIGDG 180
  181 ATDMEACPPA DAFIGFGGNV IRQQVKDNAK WYITDFVELL GELEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.221849
Match:	1nnlA
Description:	Phosphoserine phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoserine phosphatase activity	2.609399110972	bayes_pls_golite062009
hydrolase activity	1.64652153606264	bayes_pls_golite062009
catalytic activity	1.55296860681783	bayes_pls_golite062009
transporter activity	1.14896368703744	bayes_pls_golite062009
transmembrane transporter activity	1.05797491861618	bayes_pls_golite062009
substrate-specific transporter activity	0.993187180025513	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.927418188183455	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.90274219445561	bayes_pls_golite062009
ion transmembrane transporter activity	0.877641462417465	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.851191468282636	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	0.787963367346595	bayes_pls_golite062009
cation transmembrane transporter activity	0.579515117605331	bayes_pls_golite062009
ATPase activity, coupled	0.53313021679328	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.506075412583888	bayes_pls_golite062009
calcium ion transmembrane transporter activity	0.493750063720989	bayes_pls_golite062009
active transmembrane transporter activity	0.478053552351263	bayes_pls_golite062009
pyrophosphatase activity	0.457373743206143	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.436378691321164	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.435443892463434	bayes_pls_golite062009
ATPase activity	0.430637728534119	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.403861776663831	bayes_pls_golite062009
primary active transmembrane transporter activity	0.402056642959593	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.375649206782765	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.375649206782765	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.374004042755094	bayes_pls_golite062009
binding	0.309823128403058	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.273204868537985	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.204834938376666	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.117331448391929	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: