| Protein: | AK2H_ECOLI |
| Organism: | Escherichia coli |
| Length: | 810 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AK2H_ECOLI.
| Description | E-value | Query Range |
Subject Range |
|
|
738.0 | [0..12] | [810..87] |
|
|
734.0 | [0..5] | [810..83] |
|
|
732.0 | [0..12] | [810..95] |
|
|
727.0 | [0..12] | [810..94] |
|
|
722.0 | [0..11] | [810..86] |
|
|
707.0 | [0..6] | [805..21] |
|
Region A: Residues: [1-454] |
1 11 21 31 41 51
| | | | | |
1 MSVIAQAGAK GRQLHKFGGS SLADVKCYLR VAGIMAEYSQ PDDMMVVSAA GSTTNQLINW 60
61 LKLSQTDRLS AHQVQQTLRR YQCDLISGLL PAEEADSLIS AFVSDLERLA ALLDSGINDA 120
121 VYAEVVGHGE VWSARLMSAV LNQQGLPAAW LDAREFLRAE RAAQPQVDEG LSYPLLQQLL 180
181 VQHPGKRLVV TGFISRNNAG ETVLLGRNGS DYSATQIGAL AGVSRVTIWS DVAGVYSADP 240
241 RKVKDACLLP LLRLDEASEL ARLAAPVLHA RTLQPVSGSE IDLQLRCSYT PDQGSTRIER 300
301 VLASGTGARI VTSHDDVCLI EFQVPASQDF KLAHKEIDQI LKRAQVRPLA VGVHNDRQLL 360
361 QFCYTSEVAD SALKILDEAG LPGELRLRQG LALVAMVGAG VTRNPLHCHR FWQQLKGQPV 420
421 EFTWQSDDGI SLVAVLRTGP TESLIQGLHQ SVFR
|
| Detection Method: |  |
| Confidence: | 90.221849 |
| Match: | 2hmfA |
| Description: | No description for 2hmfA was found. |
| Term | Confidence | Notes |
| acetolactate synthase activity | 6.25735158730374 | bayes_pls_golite062009 |
| transferase activity, transferring aldehyde or ketonic groups | 5.28856942236052 | bayes_pls_golite062009 |
| aspartate kinase activity | 3.23731032633773 | bayes_pls_golite062009 |
| kinase activity | 3.13431949100327 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 2.94061415123563 | bayes_pls_golite062009 |
| catalytic activity | 2.83338756483354 | bayes_pls_golite062009 |
| phosphotransferase activity, carboxyl group as acceptor | 2.65970393362911 | bayes_pls_golite062009 |
| transcription regulator activity | 2.54193538468834 | bayes_pls_golite062009 |
| amino acid kinase activity | 2.38310367076654 | bayes_pls_golite062009 |
| transferase activity | 2.34413838821786 | bayes_pls_golite062009 |
| nucleic acid binding | 1.77420728550693 | bayes_pls_golite062009 |
| DNA binding | 1.70654139251388 | bayes_pls_golite062009 |
| binding | 1.61057316956254 | bayes_pls_golite062009 |
| acetylglutamate kinase activity | 1.28891782911186 | bayes_pls_golite062009 |
| transcription factor activity | 1.13755026342338 | bayes_pls_golite062009 |
| transcription repressor activity | 0.61058430787131 | bayes_pls_golite062009 |
| glutamate 5-kinase activity | 0.416864856459166 | bayes_pls_golite062009 |
| protein binding | 0.178881469836152 | bayes_pls_golite062009 |
|
Region A: Residues: [455-810] |
1 11 21 31 41 51
| | | | | |
1 AEKRIGLVLF GKGNIGSRWL ELFAREQSTL SARTGFEFVL AGVVDSRRSL LSYDGLDASR 60
61 ALAFFNDEAV EQDEESLFLW MRAHPYDDLV VLDVTASQQL ADQYLDFASH GFHVISANKL 120
121 AGASDSNKYR QIHDAFEKTG RHWLYNATVG AGLPINHTVR DLIDSGDTIL SISGIFSGTL 180
181 SWLFLQFDGS VPFTELVDQA WQQGLTEPDP RDDLSGKDVM RKLVILAREA GYNIEPDQVR 240
241 VESLVPAHCE GGSIDHFFEN GDELNEQMVQ RLEAAREMGL VLRYVARFDA NGKARVGVEA 300
301 VREDHPLASL LPCDNVFAIE SRWYRDNPLV IRGPGAGRDV TAGAIQSDIN RLAQLL
|
| Detection Method: | |
| Confidence: | 68.522879 |
| Match: | 1q7gA |
| Description: | Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| aspartate-semialdehyde dehydrogenase activity | 2.99580112154281 | bayes_pls_golite062009 |
| dihydrodipicolinate reductase activity | 2.74085594134831 | bayes_pls_golite062009 |
| catalytic activity | 2.54843319568228 | bayes_pls_golite062009 |
| transcription regulator activity | 1.90939908578582 | bayes_pls_golite062009 |
| oxidoreductase activity | 1.84451425136793 | bayes_pls_golite062009 |
| DNA binding | 1.61355789916908 | bayes_pls_golite062009 |
| nucleic acid binding | 1.48478425318425 | bayes_pls_golite062009 |
| binding | 1.22114607236074 | bayes_pls_golite062009 |
| transcription factor activity | 0.91090893050278 | bayes_pls_golite062009 |
| phosphoglycerate dehydrogenase activity | 0.639509916626856 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors | 0.610531769148819 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | 0.610013758225609 | bayes_pls_golite062009 |
| saccharopine dehydrogenase activity | 0.495113665163626 | bayes_pls_golite062009 |
| ketol-acid reductoisomerase activity | 0.414784304540676 | bayes_pls_golite062009 |
| structural molecule activity | 0.160242197882814 | bayes_pls_golite062009 |
| N-acetyl-gamma-glutamyl-phosphate reductase activity | 0.0651785123513661 | bayes_pls_golite062009 |
