YRC Public Data Repository - Protein Structure Prediction

Protein:	ATPE_ECOLI
Organism:	Escherichia coli
Length:	139 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATPE_ECOLI.

Description	E-value	Query Range	Subject Range
ATPE_JASNU - ATP synthase epsilon chain, chloroplastic OS=Jasminum nudiflorum GN=atpE PE=3 SV=1	164.0	[0..3]	[136..1]
ATPE_SPIOL - ATP synthase epsilon chain, chloroplastic OS=Spinacia oleracea GN=atpE PE=1 SV=1	164.0	[0..3]	[136..1]
ATPE_SOYBN - ATP synthase epsilon chain, chloroplastic OS=Glycine max GN=atpE PE=3 SV=1	164.0	[0..3]	[136..1]
gi\|110456644 - gi\|110456644\|gb\|ABG74763.1\| ATPase epsilon subunit [Jasminum leratii]	163.0	[0..3]	[136..1]
gi\|110456681 - gi\|110456681\|gb\|ABG74790.1\| ATPase epsilon subunit [Jasminum abyssinicum]	163.0	[0..3]	[136..1]
gi\|69215466, gi\|... - gi\|85540810\|gb\|ABC70762.1\| ATP synthase CF1 epsilon subunit [Ranunculus macranthus], gi\|69215466\|gb\|...	162.0	[0..3]	[135..1]
ATPE_NYMAL - ATP synthase epsilon chain, chloroplastic OS=Nymphaea alba GN=atpE PE=3 SV=1	162.0	[0..3]	[136..1]
gi\|110456713 - gi\|110456713\|gb\|ABG74816.1\| ATPase epsilon subunit [Jasminum subhumile]	162.0	[0..3]	[136..1]
ATPE_PIPCE - ATP synthase epsilon chain, chloroplastic OS=Piper cenocladum GN=atpE PE=3 SV=1	162.0	[0..3]	[136..1]
ATPE_GOSHI - ATP synthase epsilon chain, chloroplastic OS=Gossypium hirsutum GN=atpE PE=3 SV=1 ATPE_GOSBA - ATP synthase epsilon chain, chloroplastic OS=Gossypium barbadense GN=atpE PE=3 SV=1	161.0	[0..3]	[136..1]

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Predicted Domain #1

Region A:
Residues: [1-139]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMTYHLDVV SAEQQMFSGL VEKIQVTGSE GELGIYPGHA PLLTAIKPGM IRIVKQHGHE  60
   61 EFIYLSGGIL EVQPGNVTVL ADTAIRGQDL DEARAMEAKR KAEEHISSSH GDVDYAQASA 120
  121 ELAKAIAQLR VIELTKKAM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.39794
Match:	1bshA
Description:	Epsilon subunit of F1F0-ATP synthase C-terminal domain; Epsilon subunit of F1F0-ATP synthase N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism	15.1720697754538	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	13.6529705629238	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	11.9026865749616	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	10.7877912738726	bayes_pls_golite062009
cation transmembrane transporter activity	7.04576606325732	bayes_pls_golite062009
ion transmembrane transporter activity	6.93719537711825	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	6.50602203414328	bayes_pls_golite062009
transporter activity	4.8547700902431	bayes_pls_golite062009
substrate-specific transporter activity	4.63538407963677	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	4.62830792765529	bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism	4.61670151363313	bayes_pls_golite062009
transmembrane transporter activity	4.61435843335343	bayes_pls_golite062009
cation-transporting ATPase activity	2.69852213608942	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.4827138122635	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.855628009778066	bayes_pls_golite062009
pyrophosphatase activity	0.794161773208528	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.778506103358595	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.776107953088367	bayes_pls_golite062009
ATPase activity	0.742244064108415	bayes_pls_golite062009
binding	0.722114655317395	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	0.687044063077645	bayes_pls_golite062009
primary active transmembrane transporter activity	0.631168739658504	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.624478110809949	bayes_pls_golite062009
active transmembrane transporter activity	0.606481520159459	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.594302421859398	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.590777866773001	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.590773381625548	bayes_pls_golite062009
ATPase activity, coupled	0.18018208923602	bayes_pls_golite062009
protein binding	0.0680638759907405	bayes_pls_golite062009
catalytic activity	0.0571176024160711	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: