






| Protein: | unc-49 |
| Organism: | Caenorhabditis elegans |
| Length: | 264 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-49.
| Description | E-value | Query Range |
Subject Range |
|
|
210.0 | [0..1] | [264..185] |
|
Region A: Residues: [1-68] |
1 11 21 31 41 51
| | | | | |
1 MCSDAYSTAE IEYKWCTSKE PNCSTAVKAD ANIELSSYKF TKICQKRTLA STSSGTYSRL 60
61 RVSFIFDR
|
| Detection Method: | |
| Confidence: | 34.69897 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [69-264] |
1 11 21 31 41 51
| | | | | |
1 DSGFYFLQIF FPASLVVVLS WISFWINRDS APSRTLIGTM TVLTETHLMT GTNRRLPPVA 60
61 YVKAVDVFLG FCYLLVILAL IEYACVAYSK KKNEDRRRRE KKTEHKPAPP TPDILHDVRL 120
121 AECTCNAAPT SIIAVIKQSN RFCVSHSHID IVSRAAFPLV FILFNTLFWL ILLYKSKRLP 180
181 YISEHEGDRC DAPDLH
|
| Detection Method: | |
| Confidence: | 26.522879 |
| Match: | 1oedE |
| Description: | Acetylcholine receptor protein, gamma chain |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| transporter activity | 0.8634160537398 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.85769987951557 | bayes_pls_golite062009 |
| channel activity | 0.82494017759356 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.82494017759356 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.699135829541381 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.69403270260693 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.68865958955334 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.67623695447613 | bayes_pls_golite062009 |
| ion channel activity | 0.675765443996379 | bayes_pls_golite062009 |
| gated channel activity | 0.60374435462213 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 0.60262355448371 | bayes_pls_golite062009 |
| ligand-gated channel activity | 0.60262355448371 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.544647628998121 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.537135922480839 | bayes_pls_golite062009 |
| cation channel activity | 0.53391585932077 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 0.463355765957441 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 0.463355765957441 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 0.26375810963714 | bayes_pls_golite062009 |
| binding | 0.227765742225932 | bayes_pls_golite062009 |