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View Structure Prediction Details

Protein: gi|23496088, gi|...
Organism: Plasmodium falciparum 3D7
Length: 484 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|23496088, gi|....

Description E-value Query
Range
Subject
Range
gi|9719448, gi|9... - gi|9719450|gb|AAF97807.1|AF282977_1 falcipain 2 [Plasmodium falciparum], gi|9719448|gb|AAF97806.1|AF...
432.0 [0..1] [484..1]
gi|62240121 - gi|62240121|gb|AAX77225.1| falcipain-2' [Plasmodium falciparum]
gi|124803848, gi... - gi|23508352|ref|NP_701021.1| falcipain-2 precursor, putative [Plasmodium falciparum 3D7], gi|2349608...
420.0 [0..1] [484..1]
gi|47606558 - gi|47606558|gb|AAT36263.1| vivapain-2 [Plasmodium vivax]
391.0 [0..1] [484..1]

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Predicted Domain #1
Region A:
Residues: [1-157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYNMDYAPH EVISQQGERF VDKYVDRKIL KNKKSLLVII SLSVLSVVGF VLFYFTPNSR  60
   61 KSDLFKNSSV ENNNDDYIIN SLLKSPNGKK FIVSKIDEAL SFYDSKKNDI NKYNEGNNNN 120
  121 NADFKGLSLF KENTPSNNFI HNKDYFINFF DNKFLMN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1k3bA
Description: Dipeptidyl peptidase I (cathepsin C), exclusion domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [158-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAEHINQFYM FIKTNNKQYN SPNEMKERFQ VFLQNAHKVN MHNNNKNSLY KKELNRFADL  60
   61 TYHEFKNKYL SLRSSKPLKN SKYL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.82
Match: 1pciA
Description: Caricain (protease omega)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [242-484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDQMNYEEVI KKYKGNENFD HAAYDWRLHS GVTPVKDQKN CGSCWAFSSI GSVESQYAIR  60
   61 KNKLITLSEQ ELVDCSFKNY GCNGGLINNA FEDMIELGGI CTDDDYPYVS DAPNLCNIDR 120
  121 CTEKYGIKNY LSVPDNKLKE ALRFLGPISI SVAVSDDFAF YKEGIFDGEC GDQLNHAVML 180
  181 VGFGMKEIVN PLTKKGEKHY YYIIKNSWGQ QWGERGFINI ETDESGLMRK CGLGTDAFIP 240
  241 LIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 1yvbA
Description: No description for 1yvbA was found.

Predicted functions:

Term Confidence Notes
peptidase activity 4.90619850296986 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.64381885397949 bayes_pls_golite062009
endopeptidase activity 3.75054525912786 bayes_pls_golite062009
hydrolase activity 3.74079711298952 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
binding 1.29265216891074 bayes_pls_golite062009
cytoskeletal protein binding 1.12653729823589 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.774177093888744 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.649171767629235 bayes_pls_golite062009
thiolester hydrolase activity 0.59115205419466 bayes_pls_golite062009
kininogen binding 0.41283715939055 bayes_pls_golite062009
signal transducer activity 0.12644030784065 bayes_pls_golite062009
molecular transducer activity 0.12644030784065 bayes_pls_golite062009
structural molecule activity 0.102555314244558 bayes_pls_golite062009
tubulin binding 0.0482209771629902 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009
microtubule binding 0.00635493133568055 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle