YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29141449, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Length:	577 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29141449, gi|....

Description	E-value	Query Range	Subject Range
SYR_SALPA - Arginine--tRNA ligase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=argS PE=3 SV=1 SYR_SALPA - Arginine--tRNA ligase OS=Salmonella paratyphi A GN=argS PE=3 SV=1 gi\|213426390 - gi\|213426390\|ref\|ZP_03359140.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar... gi\|213163291 - gi\|213163291\|ref\|ZP_03349001.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar... SYR_SALPK - Arginine--tRNA ligase OS=Salmonella paratyphi A (strain AKU_12601) GN=argS PE=3 SV=1	0.0	[1..577]	[1..577]
gi\|167994213, gi... - gi\|205327860\|gb\|EDZ14624.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar 4,[... SYR_SALTS - Arginine--tRNA ligase OS=Salmonella typhimurium (strain SL1344) GN=argS PE=3 SV=1 lcl\|NC_016856.1_... - [gene=argS] [protein=arginyl-tRNA synthetase] [protein_id=YP_005237875.1] [location=2014001..2015734... SYR_SALTY - Arginyl-tRNA synthetase OS=Salmonella typhimurium GN=argS PE=3 SV=2 SYR_SALTY - Arginine--tRNA ligase OS=Salmonella typhimurium GN=argS PE=3 SV=1 SYR_SALTY - Arginine--tRNA ligase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=argS PE=3 S...	0.0	[1..577]	[1..577]
SYR_SALCH - Arginine--tRNA ligase OS=Salmonella choleraesuis (strain SC-B67) GN=argS PE=3 SV=1 SYR_SALCH - Arginyl-tRNA synthetase OS=Salmonella choleraesuis GN=argS PE=3 SV=1 SYR_SALCH - Arginine--tRNA ligase OS=Salmonella choleraesuis GN=argS PE=3 SV=1 SYR_SALHS - Arginine--tRNA ligase OS=Salmonella heidelberg (strain SL476) GN=argS PE=3 SV=1 gi\|205339146, gi... - gi\|205339146\|gb\|EDZ25910.1\| arginyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Hei...	0.0	[1..577]	[1..577]
SYR_SHIBS - Arginine--tRNA ligase OS=Shigella boydii serotype 4 (strain Sb227) GN=argS PE=3 SV=1	0.0	[1..577]	[1..577]
SYR_SHIDS - Arginine--tRNA ligase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=argS PE=3 SV=1	0.0	[1..577]	[1..577]
SYR_ECOLI - Arginyl-tRNA synthetase (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS) - Escherichia coli EG10071 - arginyl-tRNA synthetase / Arginine--tRNA ligase gi\|1736522, gi\|8... - gi\|89108716\|ref\|AP_002496.1\| arginyl-tRNA synthetase [Escherichia coli str. K-12 substr. W3110], gi\|... EG10071 - arginyl-tRNA synthetase / Arginine--tRNA ligase gi\|194417652, gi... - gi\|194434108\|ref\|ZP_03066377.1\| arginyl-tRNA synthetase [Shigella dysenteriae 1012], gi\|194417652\|gb... gi\|242377597, gi... - gi\|251785324\|ref\|YP_002999628.1\| hypothetical protein B21_01836 [Escherichia coli BL21], gi\|24237759... gi\|188488834, gi... - gi\|188493635\|ref\|ZP_03000905.1\| arginyl-tRNA synthetase [Escherichia coli 53638], gi\|188488834\|gb\|ED... SYR_ECOBW - Arginine--tRNA ligase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=argS PE=3 SV=1 SYR_ECODH - Arginine--tRNA ligase OS=Escherichia coli (strain K12 / DH10B) GN=argS PE=3 SV=1 gi\|254161936, gi... - gi\|254161936\|ref\|YP_003045044.1\| arginyl-tRNA synthetase [Escherichia coli B str. REL606], gi\|253973... gi\|253324211, gi... - gi\|254288724\|ref\|YP_003054472.1\| arginyl-tRNA synthetase [Escherichia coli BL21(DE3)], gi\|253978031\|...	0.0	[1..577]	[1..577]
gi\|254793500, gi... - gi\|254793500\|ref\|YP_003078337.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14359], gi... SYR_ECO57 - Arginine--tRNA ligase OS=Escherichia coli O157:H7 GN=argS PE=3 SV=1 gi\|208810380, gi... - gi\|208810380\|ref\|ZP_03252256.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206], gi\|2... gi\|195939580 - gi\|195939580\|ref\|ZP_03084962.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|189376028, gi... - gi\|189376028\|gb\|EDU94444.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC508], gi\|168801... gi\|168789744, gi... - gi\|189370702\|gb\|EDU89118.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC869], gi\|168789... gi\|209767330, gi... - pir\|\|B90952 arginine tRNA synthetase [imported] - Escherichia coli (strain O157:H7, substrain RIMD ... SYR_ECO5E - Arginine--tRNA ligase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=argS PE=3 SV=1 gi\|208818546, gi... - gi\|208818546\|ref\|ZP_03258866.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4042], gi\|2... gi\|13362054, gi\|... - gi\|15831840\|ref\|NP_310613.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|13362... gi\|208731065, gi... - gi\|208816722\|ref\|ZP_03257842.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045], gi\|2... gi\|188017552, gi... - gi\|188017552\|gb\|EDU55674.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4113], gi\|16874... gi\|188999443, gi... - gi\|188999443\|gb\|EDU68429.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi\|16878... gi\|187768070, gi... - gi\|187768070\|gb\|EDU31914.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi\|16877... gi\|189360270, gi... - gi\|189360270\|gb\|EDU78689.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi\|16877... gi\|168757913, gi... - gi\|189355181\|gb\|EDU73600.1\| arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4401], gi\|16875...	0.0	[1..577]	[1..577]
SYR_ECOL6 - Arginine--tRNA ligase OS=Escherichia coli O6 GN=argS PE=3 SV=1 gi\|124498822, gi... - gi\|124531083\|ref\|ZP_01701468.1\| arginyl-tRNA synthetase [Escherichia coli B], gi\|124498822\|gb\|EAY463... gi\|194439027, gi... - gi\|194439027\|ref\|ZP_03071110.1\| arginyl-tRNA synthetase [Escherichia coli 101-1], gi\|194421986\|gb\|ED... gi\|227837269, gi... - gi\|227885696\|ref\|ZP_04003501.1\| arginyl-tRNA synthetase [Escherichia coli 83972], gi\|227837269\|gb\|EE... SYR_ECOSE - Arginine--tRNA ligase OS=Escherichia coli (strain SE11) GN=argS PE=3 SV=1 SYR_ECOLC - Arginine--tRNA ligase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=argS PE=3 SV=1 SYR_ECOL6 - Arginine--tRNA ligase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=argS PE=3 SV...	0.0	[1..577]	[1..577]
SYR_SHIF8 - Arginine--tRNA ligase OS=Shigella flexneri serotype 5b (strain 8401) GN=argS PE=3 SV=1	0.0	[1..577]	[1..577]
gi\|30041576, gi\|... - gi\|30063324\|ref\|NP_837495.1\| arginyl-tRNA synthetase [Shigella flexneri 2a str. 2457T], gi\|30041576\|... gi\|24052255, gi\|... - gi\|24113254\|ref\|NP_707764.1\| arginyl-tRNA synthetase [Shigella flexneri 2a str. 301], gi\|24052255\|gb... SYR_SHIFL - Arginine--tRNA ligase OS=Shigella flexneri GN=argS PE=3 SV=1	0.0	[1..577]	[1..577]

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Predicted Domain #1

Region A:
Residues: [1-577]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIQALLSEK VSQAMIAAGA PADCEPQVRQ SAKVQFGDYQ ANGMMAVAKK LGMAPRQLAE  60
   61 QVLTHLDLSG IASKVEIAGP GFINIFLEPA FLAEQVQQAL TSDRLGVSQP TRQTIVVDYS 120
  121 APNVAKEMHV GHLRSTIIGD AAVRTLEFLG HHVIRANHVG DWGTQFGMLI AWLEKQQQEN 180
  181 AGDMALADLE GFYRDAKKHY DEDETFAERA RNYVVKLQSG DTYFREMWRK LVDITMTQNQ 240
  241 ITYDRLNVTL TRDDVMGESL YNPMLPGIVA DLKAKGLAVE SEGATVVFLD EFKNKEGDPM 300
  301 GVIIQKKDGG YLYTTTDIAC AKYRYETLHA DRVLYYIDSR QHQHLMQAWT IVRKAGYVPD 360
  361 SVPLEHHMFG MMLGKDGKPF KTRTGGTVKL ADLLDEALER ARRLVAEKNP DMPADELEKL 420
  421 ANAVGIGAVK YADLSKNRTT DYIFDWDNML AFEGNTAPYM QYAYTRVLSV FRKADIDEQA 480
  481 LASAPVIISE DREAQLAARL LQFEETLTVV AREGTPHVMC AYLYDVAGLF SGFYEHCPIL 540
  541 SAENDAVRNS RLKLAQLTAK TLKLGLDTLG IETVERM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.154902
Match:	1bs2A
Description:	Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
arginine-tRNA ligase activity	5.72854650987135	bayes_pls_golite062009
isoleucine-tRNA ligase activity	3.76808520367507	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
nucleic acid binding	1.03251266786448	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
nucleotidyltransferase activity	0.564359271862248	bayes_pls_golite062009
binding	0.520077014845626	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: