YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30253589, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	499 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30253589, gi|....

Description	E-value	Query Range	Subject Range
gi\|221321410 - gi\|221321410\|ref\|ZP_03602704.1\| lysyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. SMY] gi\|221317147 - gi\|221317147\|ref\|ZP_03598441.1\| lysyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. JH642] gi\|221312214 - gi\|221312214\|ref\|ZP_03594019.1\| lysyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. NCIB 3... SYK_BACSU - Lysine--tRNA ligase OS=Bacillus subtilis (strain 168) GN=lysS PE=3 SV=1 SYK_BACSU - Lysine--tRNA ligase OS=Bacillus subtilis GN=lysS PE=3 SV=1	0.0	[2..497]	[4..499]
SYK_BACCN - Lysine--tRNA ligase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) GN...	0.0	[1..499]	[1..499]
gi\|52078577, gi\|... - gi\|52783938\|ref\|YP_089767.1\| lysyl-tRNA synthetase [Bacillus licheniformis ATCC 14580], gi\|52346440\|...	0.0	[2..497]	[4..499]
gi\|229329178, gi... - gi\|229499899\|ref\|ZP_04393576.1\| lysyl-tRNA synthetase [Geobacillus sp. Y412MC52], gi\|229329178\|gb\|EE... gi\|56378451, gi\|... - gi\|56418609\|ref\|YP_145927.1\| lysyl-tRNA synthetase [Geobacillus kaustophilus HTA426], gi\|56378451\|db... gi\|220708025, gi... - gi\|221088032\|ref\|ZP_03557566.1\| lysyl-tRNA synthetase [Geobacillus sp. Y412MC61], gi\|220708025\|gb\|EE...	0.0	[4..497]	[1..494]
gi\|228809100, gi... - gi\|228950625\|ref\|ZP_04112760.1\| Lysyl-tRNA synthetase [Bacillus thuringiensis serovar kurstaki str. ... gi\|228956518, gi... - gi\|228956518\|ref\|ZP_04118315.1\| Lysyl-tRNA synthetase [Bacillus thuringiensis serovar pakistani str.... gi\|228919027, gi... - gi\|228919027\|ref\|ZP_04082407.1\| Lysyl-tRNA synthetase [Bacillus thuringiensis serovar huazhongensis ... gi\|228657911, gi... - gi\|229125594\|ref\|ZP_04254627.1\| Lysyl-tRNA synthetase [Bacillus cereus BDRD-Cer4], gi\|228657911\|gb\|E... gi\|229142883, gi... - gi\|229142883\|ref\|ZP_04271325.1\| Lysyl-tRNA synthetase [Bacillus cereus BDRD-ST24], gi\|228640595\|gb\|E... gi\|229039982, gi... - gi\|229039982\|ref\|ZP_04189746.1\| Lysyl-tRNA synthetase [Bacillus cereus AH676], gi\|228727390\|gb\|EEL78... gi\|228675736, gi... - gi\|229107763\|ref\|ZP_04237400.1\| Lysyl-tRNA synthetase [Bacillus cereus Rock1-15], gi\|228675736\|gb\|EE... gi\|229176677, gi... - gi\|229176677\|ref\|ZP_04304082.1\| Lysyl-tRNA synthetase [Bacillus cereus 172560W], gi\|228606844\|gb\|EEK... gi\|228595161, gi... - gi\|229188362\|ref\|ZP_04315411.1\| Lysyl-tRNA synthetase [Bacillus cereus ATCC 10876], gi\|228595161\|gb\|... SYK_BACCR - Lysine--tRNA ligase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9... SYK_BACC4 - Lysine--tRNA ligase OS=Bacillus cereus (strain B4264) GN=lysS PE=3 SV=1 gi\|206972583, gi... - gi\|206972583\|ref\|ZP_03233526.1\| lysyl-tRNA synthetase [Bacillus cereus AH1134], gi\|206732485\|gb\|EDZ4...	0.0	[1..499]	[1..499]
gi\|229053923, gi... - gi\|229053923\|ref\|ZP_04195358.1\| Lysyl-tRNA synthetase [Bacillus cereus AH603], gi\|228721464\|gb\|EEL72... SYK_BACWK - Lysine--tRNA ligase OS=Bacillus weihenstephanensis (strain KBAB4) GN=lysS PE=3 SV=1 gi\|229009586, gi... - gi\|229009586\|ref\|ZP_04166813.1\| Lysyl-tRNA synthetase [Bacillus mycoides DSM 2048], gi\|228751730\|gb\|... gi\|228618450, gi... - gi\|229165065\|ref\|ZP_04292861.1\| Lysyl-tRNA synthetase [Bacillus cereus AH621], gi\|228618450\|gb\|EEK75...	0.0	[1..499]	[1..499]
SYK_GEOSE - Lysine--tRNA ligase OS=Geobacillus stearothermophilus GN=lysS PE=1 SV=1	0.0	[4..497]	[1..494]
gi\|222093847, gi... - gi\|222093847\|ref\|YP_002527896.1\| lysyl-tRNA synthetase [Bacillus cereus Q1], gi\|221237894\|gb\|ACM1060... SYK_BACC7 - Lysine--tRNA ligase OS=Bacillus cereus (strain AH187) GN=lysS PE=3 SV=1 gi\|206743832, gi... - gi\|206977926\|ref\|ZP_03238813.1\| lysyl-tRNA synthetase [Bacillus cereus H3081.97], gi\|206743832\|gb\|ED... gi\|228589057, gi... - gi\|229194467\|ref\|ZP_04321271.1\| Lysyl-tRNA synthetase [Bacillus cereus m1293], gi\|228589057\|gb\|EEK47... SYK_BACC1 - Lysine--tRNA ligase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=lysS PE=3 SV=1 gi\|228646588, gi... - gi\|229136923\|ref\|ZP_04265551.1\| Lysyl-tRNA synthetase [Bacillus cereus BDRD-ST26], gi\|228646588\|gb\|E...	0.0	[1..499]	[1..499]
gi\|47570201, gi\|... - gi\|47570201\|ref\|ZP_00240855.1\| lysyl-tRNA synthetase [Bacillus cereus G9241], gi\|47553145\|gb\|EAL1154... gi\|228776446, gi... - gi\|228983332\|ref\|ZP_04143546.1\| Lysyl-tRNA synthetase [Bacillus thuringiensis serovar tochigiensis B...	0.0	[1..499]	[1..499]
gi\|47093173, gi\|... - gi\|47093173\|ref\|ZP_00230948.1\| lysyl-tRNA synthetase [Listeria monocytogenes str. 4b H7858], gi\|4701...	0.0	[1..497]	[1..497]

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Predicted Domain #1

Region A:
Residues: [1-499]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNMNHEELN DQLLVRREKL HNLREQGIDP FGKRFERTNA TNDLLSLYGE FSKEELEEKE  60
   61 ISVSIAGRIM TKRGKGKAGF AHIQDLHGQV QIYVRKDAVG DEEYELFKTA DLGDLVGIEG 120
  121 KVFKTNVGEL SVKATGFTLL TKSLRPLPDK YHGLKDVEQR YRQRYLDLIT SMESRETFVT 180
  181 RSKIIREMRR YLDDNGYLEV ETPMMHAIAG GASARPFITH HNALDMELYM RIAIELHLKR 240
  241 LIVGGLEKVY EIGRVFRNEG VSTRHNPEFT MIELYEAYAD YKDIMKLTEN MVAHIAKQVL 300
  301 GTTTIQYGDY EINLEPEWTR LHMVDAIKEH SGADFWNPMS VEEARELAKE HNVEIKDTME 360
  361 VGHIINEFFE QKVEDKLIQP TFIYGHPVEI SPLAKKNDED PRFTDRFELF IVAREHANAF 420
  421 TELNDPIDQK ERFEAQLKER EQGNDEAHMM DDDYIEALEY GMPPTGGLGI GIDRLVMLLT 480
  481 NAPSIRDVLL FPAMRHKQD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	154.0
Match:	1bbuA
Description:	Lysyl-tRNA synthetase (LysRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.89468709683036	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.89468709683036	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.88410036819636	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
lysine-tRNA ligase activity	5.79033103181143	bayes_pls_golite062009
asparagine-tRNA ligase activity	5.29805946490109	bayes_pls_golite062009
aspartate-tRNA ligase activity	3.80084837437429	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	2.99105702052936	bayes_pls_golite062009
serine-tRNA ligase activity	2.46505535069103	bayes_pls_golite062009
structural constituent of ribosome	2.43759174701552	bayes_pls_golite062009
glycine-tRNA ligase activity	2.29229136935761	bayes_pls_golite062009
threonine-tRNA ligase activity	2.18642354927	bayes_pls_golite062009
structural molecule activity	2.08258913217268	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
histidine-tRNA ligase activity	1.72215103383322	bayes_pls_golite062009
translation initiation factor activity	0.96756670903925	bayes_pls_golite062009
single-stranded DNA binding	0.56590887755068	bayes_pls_golite062009
binding	0.521863822270226	bayes_pls_golite062009
transcription regulator activity	0.375542987753806	bayes_pls_golite062009
ribonuclease activity	0.305684604963838	bayes_pls_golite062009
nucleic acid binding	0.281662799812287	bayes_pls_golite062009
DNA binding	0.0309732052586011	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: