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View Structure Prediction Details

Protein: PNP_PSEAE
Organism: Pseudomonas aeruginosa
Length: 701 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNP_PSEAE.

Description E-value Query
Range		 Subject
Range
PNP_METFK - Polyribonucleotide nucleotidyltransferase OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / D...
 0.0 [1..700] [1..699]
PNP_PSEA7 - Polyribonucleotide nucleotidyltransferase OS=Pseudomonas aeruginosa (strain PA7) GN=pnp PE=3 SV=1
 0.0 [1..701] [1..701]
gi|25311841, gi|... - pir||AE2586 polyribonucleotide nucleotidyltransferase pnpA [imported] - Agrobacterium tumefaciens (s...
PNP_AGRFC - Polyribonucleotide nucleotidyltransferase OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=pnp P...
 0.0 [2..701] [3..701]
gi|78701235, gi|... - gi|78701235|ref|ZP_00865687.1| Polyribonucleotide nucleotidyltransferase [Alkalilimnicola ehrlichei ...
 0.0 [5..697] [27..720]
PNP_RHIL3 - Polyribonucleotide nucleotidyltransferase OS=Rhizobium leguminosarum bv. viciae (strain 3841) GN=pnp...
 0.0 [4..701] [5..701]
PNP_RHILO - Polyribonucleotide nucleotidyltransferase OS=Rhizobium loti (strain MAFF303099) GN=pnp PE=3 SV=1
PNP_RHILO - Polyribonucleotide nucleotidyltransferase OS=Rhizobium loti GN=pnp PE=3 SV=1
 0.0 [2..701] [3..702]
PNP_CHESB - Polyribonucleotide nucleotidyltransferase OS=Chelativorans sp. (strain BNC1) GN=pnp PE=3 SV=1
 0.0 [2..701] [3..702]
PNP_BARBK - Polyribonucleotide nucleotidyltransferase OS=Bartonella bacilliformis (strain ATCC 35685 / KC583) GN...
 0.0 [4..701] [5..702]
gi|90335247, gi|... - gi|90420519|ref|ZP_01228426.1| polyribonucleotide nucleotidyltransferase [Aurantimonas sp. SI85-9A1]...
gi|90335247, gi|... - gi|90420519|ref|ZP_01228426.1| polyribonucleotide nucleotidyltransferase [Aurantimonas sp. SI85-9A1]...
 0.0 [4..701] [5..702]
gi|85714171, gi|... - gi|85714171|ref|ZP_01045160.1| polyribonucleotide nucleotidyltransferase [Nitrobacter sp. Nb-311A], ...
 0.0 [3..701] [9..706]

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Predicted Domain #1
Region A:
Residues: [1-701] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPVTKQFQF GQSTVTLETG RIARQATGAV LVTMDDVSVL VTVVGAKSPA EGRDFFPLSV  60
   61 HYQEKTYAAG RIPGGFFKRE GRPSEKETLT SRLIDRPIRP LFPEGFMNEV QVVCTVVSTN 120
  121 KKSDPDIAAM IGTSAALAIS GIPFAGPIGA ARVGFHPEIG YILNPTYEQL QSSSLDMVVA 180
  181 GTEDAVLMVE SEADELTEDQ MLGAVLFAHD EFQAVIRAVK ELAAEAGKPA WDWKAPAENT 240
  241 VLVNAIKAEL GEAISQAYTI TIKQDRYNRL GELRDQAVAL FAGEEEGKFP ASEVKDVFGL 300
  301 LEYRTVRENI VNGKPRIDGR DTRTVRPLRI EVGVLGKTHG SALFTRGETQ ALVVATLGTA 360
  361 RDAQLLDTLE GERKDAFMLH YNFPPFSVGE CGRMGSPGRR EIGHGRLARR GVAAMLPTQD 420
  421 EFPYTIRVVS EITESNGSSS MASVCGASLA LMDAGVPVKA PVAGIAMGLV KEGEKFAVLT 480
  481 DILGDEDHLG DMDFKVAGTD KGVTALQMDI KINGITEEIM EIALGQALEA RLNILGQMNQ 540
  541 VIAKPRAELS ENAPTMLQMK IDSDKIRDVI GKGGATIRGI CEETKASIDI EDDGSVKIYG 600
  601 ETKEAAEAAK LRVLAITAEA EIGKIYVGKV ERIVDFGAFV NILPGKDGLV HISQISDKRI 660
  661 DKVTDVLQEG QEVKVLVLDV DNRGRIKLSI KDVAAAEASG V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 157.0
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 3.62650207668685 bayes_pls_golite062009
transcription regulator activity 2.64513435028798 bayes_pls_golite062009
exoribonuclease activity 2.49584565422948 bayes_pls_golite062009
3'-5'-exoribonuclease activity 2.48625785660839 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 2.46667410843173 bayes_pls_golite062009
RNA binding 1.96263727771326 bayes_pls_golite062009
nucleic acid binding 1.06121115244578 bayes_pls_golite062009
transcription termination factor activity 1.01993495617192 bayes_pls_golite062009
binding 0.953779727473657 bayes_pls_golite062009
structural constituent of ribosome 0.82905129800799 bayes_pls_golite062009
ATP-dependent peptidase activity 0.66778558090199 bayes_pls_golite062009
structural molecule activity 0.61730676636766 bayes_pls_golite062009
carbohydrate kinase activity 0.51810239718467 bayes_pls_golite062009
DNA binding 0.42372608430605 bayes_pls_golite062009
0.416217645025381 bayes_pls_golite062009
hydrolase activity 0.355379071501158 bayes_pls_golite062009
catalytic activity 0.10089766806364 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0287026367466632 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
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