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View Structure Prediction Details

Protein: gi|30255253, gi|...
Organism: Bacillus anthracis str. Ames
Length: 371 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30255253, gi|....

Description E-value Query
Range
Subject
Range
gi|51977508, gi|... - gi|52144039|ref|YP_082790.1| carbohydrate diacid regulator [Bacillus cereus E33L], gi|51977508|gb|AA...
5.0E-84 [1..371] [1..371]
gi|228944995, gi... - gi|228944995|ref|ZP_04107356.1| Transcriptional regulator [Bacillus thuringiensis serovar monterrey ...
gi|65318664 - gi|65318664|ref|ZP_00391623.1| COG3835: Sugar diacid utilization regulator [Bacillus anthracis str. ...
gi|228932677, gi... - gi|228932677|ref|ZP_04095551.1| Transcriptional regulator [Bacillus thuringiensis serovar andalousie...
gi|229120936, gi... - gi|229120936|ref|ZP_04250178.1| Transcriptional regulator [Bacillus cereus 95/8201], gi|228662596|gb...
9.0E-84 [1..371] [4..374]
gi|42736404, gi|... - gi|42780485|ref|NP_977732.1| transcriptional regulator, putative [Bacillus cereus ATCC 10987], gi|42...
1.0E-82 [1..371] [1..371]
gi|29894993, gi|... - gi|30019449|ref|NP_831080.1| carbohydrate diacid regulator [Bacillus cereus ATCC 14579], gi|29894993...
gi|218233562, gi... - gi|218233562|ref|YP_002366080.1| putative carbohydrate diacid regulator [Bacillus cereus B4264], gi|...
1.0E-82 [1..371] [1..371]
gi|89151094, gi|... - gi|89200933|ref|ZP_01179682.1| Helix-turn-helix, Fis-type [Bacillus cereus subsp. cytotoxis NVH 391-...
1.0E-82 [1..371] [1..371]
gi|47556736, gi|... - gi|47566183|ref|ZP_00237211.1| carbohydrate diacid regulator [Bacillus cereus G9241], gi|47556736|gb...
4.0E-82 [1..371] [1..371]
gi|75760002, gi|... - gi|75760002|ref|ZP_00740069.1| Carbohydrate diacid regulator [Bacillus thuringiensis serovar israele...
7.0E-82 [1..371] [4..374]
gi|89157537, gi|... - gi|89204476|ref|ZP_01183053.1| Helix-turn-helix, Fis-type [Bacillus weihenstephanensis KBAB4], gi|89...
1.0E-79 [1..371] [1..371]
gi|23100285, gi|... - gi|23100285|ref|NP_693752.1| hypothetical protein OB2830 [Oceanobacillus iheyensis HTE831], gi|22778...
3.0E-77 [6..364] [6..366]
gi|28808253 - gi|28808253|dbj|BAC61458.1| conserved hypothetical protein [Vibrio parahaemolyticus RIMD 2210633]
gi|28899970, gi|... - gi|28899970|ref|NP_799625.1| hypothetical protein VPA0115 [Vibrio parahaemolyticus RIMD 2210633], gi...
2.0E-72 [1..359] [3..376]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFPDLANKI VREVRRLIKE NIIIINIQGV IIASTDIERI GQFHEGALRC AKQKKTVIIT  60
   61 KEDERRLHGV KAGMNLPLLF HDEVIGVIGI TGEPENISQY GEILRKMTEL LIHENYFLEQ 120
  121 LELEHRSYEA FVFDWL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.13
Match: 2gx5A
Description: No description for 2gx5A was found.

Predicted Domain #2
Region A:
Residues: [137-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNTDWSPSFL DRAKTLGIDL YKKKQLILFS IDQNDTMLQR KIWQHVRNLL TKEHLFVRWG  60
   61 NDRFILFTAM SSKEQTYQFL KRLKQDCETL FSIPLYIGIG QSVTPSNMNL SYEQALQALS 120
  121 VSLATKKIVF NDDLRLEMCL QD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [279-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISAETREQFL KRTIKNLLSS PELMHTLRLF IDYNQSYKQT AEQLHIHINT LHYRLKKIEE  60
   61 YTGLDPKQFK DLNILYFSLL LLDNHTKKND KID

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.22
Match: 1ntcA
Description: DNA-binding domain of NTRC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.3433274000438 bayes_pls_golite062009
DNA binding 2.69924718143396 bayes_pls_golite062009
binding 2.59564404935518 bayes_pls_golite062009
nucleic acid binding 2.49248256652331 bayes_pls_golite062009
transcription factor activity 2.13079795809497 bayes_pls_golite062009
sequence-specific DNA binding 0.694747504121538 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.611882179195983 bayes_pls_golite062009
protein binding 0.440093783038461 bayes_pls_golite062009
transcription repressor activity 0.382260654915774 bayes_pls_golite062009
transcription activator activity 0.249743327112707 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle