YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30260106, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	410 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30260106, gi|....

Description	E-value	Query Range	Subject Range
gi\|50745842 - gi\|50745842\|ref\|XP_420265.1\| PREDICTED: similar to chloride channel CLC-5 [Gallus gallus]	1.0E-81	[2..406]	[951..1466]
gi\|74006441 - gi\|74006441\|ref\|XP_856046.1\| PREDICTED: similar to Chloride channel protein 4 (ClC-4) isoform 4 [Can...	3.0E-81	[12..406]	[71..549]
gi\|74177944, gi\|... - gi\|74177944\|dbj\|BAE29767.1\| unnamed protein product [Mus musculus], gi\|74141979\|dbj\|BAE41053.1\| unna...	6.0E-81	[12..406]	[129..627]
gi\|119625190, gi... - gi\|55770840\|ref\|NP_776297.2\| chloride channel 3 isoform e [Homo sapiens], gi\|119625190\|gb\|EAX04785.1... gi\|114596816 - gi\|114596816\|ref\|XP_001153846.1\| PREDICTED: chloride channel 3 isoform 3 [Pan troglodytes]	7.0E-81	[12..406]	[129..627]
gi\|220061722, gi... - gi\|47210785\|emb\|CAF91095.1\| unnamed protein product [Tetraodon nigroviridis], gi\|220061722\|gb\|ACL795...	1.0E-80	[12..406]	[106..593]
gi\|114596822 - gi\|114596822\|ref\|XP_001154032.1\| PREDICTED: similar to chloride channel 3 isoform 6 [Pan troglodytes...	3.0E-80	[12..406]	[102..600]

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Predicted Domain #1

Region A:
Residues: [1-410]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNTKDMHYM LVLYGILLGS IVGATVWLFL VTINIGIHFI WEYLPTIFAS PPYYTICVTT  60
   61 IGGILVGLTQ KYFGTYPRLM PEVMGEYKKT GRIEYRFVHK ATLTAIIVLI FGASLGPEAA 120
  121 LVGIIGGLCT WVGDRFTFAL KGMNGLTEVG IGATLSVIFN APLFGYLAPN ENEGEQINEF 180
  181 SKGKKAIVYL ATTFAGFSVY LLLSKFDNRG SFIVDFGKGS LSLNEWIAFL PLASIGAIVG 240
  241 FFYFKLEFTL EKLIHPLKEY KLALGIIGGI LLGITGTFLP YTLFSGEHQL KDLVVEWSHL 300
  301 SFWVLLLSGI LKLCITAVCL NTGWRGGHIF PIIFAGSSIG YAIASIIPID PIASVAVVTT 360
  361 AISSYALRKP IAITLLLLMF FPLNLLLPML GAAAIGNAFP LPKNNEATNE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.69897
Match:	1kplA
Description:	Clc chloride channel
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	1.40104538148014	bayes_pls_golite062009
transmembrane transporter activity	1.27040739514162	bayes_pls_golite062009
substrate-specific transporter activity	0.99765601803889	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.87653733645387	bayes_pls_golite062009
ion transmembrane transporter activity	0.67051140447735	bayes_pls_golite062009
anion transmembrane transporter activity	0.64978720715189	bayes_pls_golite062009
channel activity	0.37948130863591	bayes_pls_golite062009
passive transmembrane transporter activity	0.37948130863591	bayes_pls_golite062009
substrate-specific channel activity	0.374530204979559	bayes_pls_golite062009
ion channel activity	0.30974369003321	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: