YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30265425, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	417 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30265425, gi|....

Description	E-value	Query Range	Subject Range
gi\|7431122 - pir\|\|C70456 homoserine dehydrogenase (EC 1.1.1.3) - Aquifex aeolicus gi\|2984093, gi\|1... - gi\|2984093\|gb\|AAC07631.1\| homoserine dehydrogenase [Aquifex aeolicus VF5], gi\|15606863\|ref\|NP_214243...	0.0	[1..416]	[1..434]
gi\|66044538, gi\|... - gi\|66044538\|ref\|YP_234379.1\| homoserine dehydrogenase [Pseudomonas syringae pv. syringae B728a], gi\|...	0.0	[2..413]	[31..460]
gi\|254242427, gi... - gi\|254242427\|ref\|ZP_04935749.1\| homoserine dehydrogenase [Pseudomonas aeruginosa 2192], gi\|194553412... gi\|126168577, gi... - gi\|254236646\|ref\|ZP_04929969.1\| homoserine dehydrogenase [Pseudomonas aeruginosa C3719], gi\|19454763... gi\|115586955, gi... - gi\|116051734\|ref\|YP_789427.1\| homoserine dehydrogenase [Pseudomonas aeruginosa UCBPP-PA14], gi\|11558...	0.0	[1..413]	[1..431]
gi\|218889986, gi... - gi\|218889986\|ref\|YP_002438850.1\| homoserine dehydrogenase [Pseudomonas aeruginosa LESB58], gi\|218770... DHOM_PSEAE - Homoserine dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12... DHOM_PSEAE - Homoserine dehydrogenase OS=Pseudomonas aeruginosa GN=hom PE=3 SV=2	0.0	[1..413]	[1..431]
gi\|71735728, gi\|... - gi\|71735728\|ref\|YP_273618.1\| homoserine dehydrogenase [Pseudomonas syringae pv. phaseolicola 1448A],...	0.0	[1..413]	[1..431]
tr\|Q886U6\|Q886U6... - Homoserine dehydrogenase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=hom PE=3 SV=1 gi\|28868687, gi\|... - gi\|28868687\|ref\|NP_791306.1\| homoserine dehydrogenase [Pseudomonas syringae pv. tomato str. DC3000],... gi\|213926060, gi... - gi\|213969062\|ref\|ZP_03397201.1\| homoserine dehydrogenase [Pseudomonas syringae pv. tomato T1], gi\|21...	0.0	[1..413]	[1..431]
gi\|24982941, gi\|... - gi\|26988203\|ref\|NP_743628.1\| homoserine dehydrogenase [Pseudomonas putida KT2440], gi\|24982941\|gb\|AA... gi\|82714907, gi\|... - gi\|82738016\|ref\|ZP_00900857.1\| homoserine dehydrogenase [Pseudomonas putida F1], gi\|82714907\|gb\|EAP4... tr\|E4RGM0\|E4RGM0... - Homoserine dehydrogenase OS=Pseudomonas putida (strain BIRD-1) GN=hom PE=3 SV=1 tr\|I7BWZ3\|I7BWZ3... - Homoserine dehydrogenase OS=Pseudomonas putida (strain DOT-T1E) GN=hom PE=3 SV=1	0.0	[1..413]	[1..431]
gi\|46121076, gi\|... - gi\|91775401\|ref\|YP_545157.1\| homoserine dehydrogenase [Methylobacillus flagellatus KT], gi\|91775257\|...	0.0	[1..414]	[1..434]
gi\|95112212 - gi\|95112212\|emb\|CAK16939.1\| homoserine dehydrogenase [Pseudomonas entomophila L48] gi\|104783225, gi... - gi\|95112212\|emb\|CAK16939.1\| homoserine dehydrogenase [Pseudomonas entomophila L48], gi\|104783225\|ref...	0.0	[2..413]	[18..447]
gi\|28211948, gi\|... - gi\|28211948\|ref\|NP_782892.1\| homoserine dehydrogenase [Clostridium tetani E88], gi\|28204391\|gb\|AAO36...	0.0	[1..413]	[1..425]

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Predicted Domain #1

Region A:
Residues: [1-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEIQVGLLG LGTVGSGVVR IITDHQERLI HQVGCPVKVT KVLVQNIEKE REVEVPSTLL  60
   61 TQDAHEILDN PNIDVVIEVM GGIDDAKAYI LQALQSGKHV VTANKDLMAL HGAELLAVAK 120
  121 DNKADLFYEA SVAGGIPILR SIVEGLSSDL ITKVMGIVNG TTNFILTKMS DEGRAYNDVL 180
  181 KEAQQLGFAE ADPTSDVEGL DAARKMTILA TLGFSTNVEL GDVKVKGITS ITEEDIEYSK 240
  241 SLGYTIKLIG LAKRDGEKLE VTVEPTLLPN THPLAAVQNE YNAVYVYGEA VGETMFYGPG 300
  301 AGSLPTATAV VSDLVAVMQN IRL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.0
Match:	1ebfA
Description:	Homoserine dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aspartate-semialdehyde dehydrogenase activity	3.92511214237139	bayes_pls_golite062009
catalytic activity	2.91887313269429	bayes_pls_golite062009
oxidoreductase activity	2.86254373278283	bayes_pls_golite062009
dihydrodipicolinate reductase activity	1.71989205356835	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.19591951564949	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1.07932840802619	bayes_pls_golite062009
ketol-acid reductoisomerase activity	0.57325534211306	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.23458869447046	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.22364954992375	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.22262673350502	bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase activity	0.0876163188309598	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [324-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVTGNSAVVP QYQKVLKEPD EIVVFAKITS LFSERGVSFE KIIQMPLEEK GKAEIVIVTH  60
   61 RASLADYDYI LHTLQGYEEI DCLKANYRIE GDAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.154902
Match:	2pc6A
Description:	No description for 2pc6A was found.

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	5.6098771388969	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	4.76464602837385	bayes_pls_golite062009
catalytic activity	1.01569611874813	bayes_pls_golite062009
transferase activity	0.07375530569672	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: