Protein Overview: DHOM_PSEAE

General Information:
Name(s) found:	DHOM_PSEAE [Swiss-Prot]
Description(s) found: Found 7 descriptions. SHOW ALL	Homoserine dehydrogenase OS=Pseudomonas aeruginosa GN=hom PE=3 SV=2 [Swiss-Prot]
Organism:	Pseudomonas aeruginosa
Length:	434 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPVKVGICG LGTVGGGTFN VLERNAEEIA RRAGRGIEVA QIAARRPNPK CDTGATPITA  60
   61 DIFDVACNPE IDVVVELIGG YTLAHELVLK AIENGKHVVT ANKALIAVHG NEIFAKAREK 120
  121 GVIVAFEAAV AGGIPVIKAI REGLSANRIN WLAGIINGTG NFILSEMREK GRTFPDVLAE 180
  181 AQALGYAEAD PTFDVEGIDA AHKLTILASI AFGIPLQFDK AYTEGISKLT SADVNYADAL 240
  241 GYRIKHLGVA RRTESGFELR VHPTLIPSDR LIANVNGVMN AVMVNGDAVG STLYYGAGAG 300
  301 MEPTASSVVA DLVDVVRAMT SDPENRVPHL AFQPDALSDH PILPIEACES AYYLRIQAKD 360
  361 HPGVLAQVAT ILSERGINIE SIMQKEAEEQ DGLVPMILVT HRVIEQRIND AIAALEALEG 420
  421 VSGPVVRIRV EQLN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..325]	PSI-BLAST	30.045757	Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline
2	View Details	[326..434]	PSI-BLAST	4.045757	Crystal structure of Acetolactate synthase- small subunit from Thermotoga maritima

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
aspartate-semialdehyde dehydrogenase activity	3.92511214237139	bayes_pls_golite062009
catalytic activity	2.91887313269429	bayes_pls_golite062009
oxidoreductase activity	2.86254373278283	bayes_pls_golite062009
dihydrodipicolinate reductase activity	1.71989205356835	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.19591951564949	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1.07932840802619	bayes_pls_golite062009
ketol-acid reductoisomerase activity	0.57325534211306	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.23458869447046	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.22364954992375	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.22262673350502	bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase activity	0.0876163188309598	bayes_pls_golite062009

2

Term	Confidence	Notes
acetolactate synthase activity	5.6098771388969	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	4.76464602837385	bayes_pls_golite062009
catalytic activity	1.01569611874813	bayes_pls_golite062009
transferase activity	0.07375530569672	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.72

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle