YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30260089, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	423 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30260089, gi|....

Description	E-value	Query Range	Subject Range
gi\|42784563, gi\|... - gi\|42784563\|ref\|NP_981810.1\| D-alanyl-D-alanine carboxypeptidase, putative [Bacillus cereus ATCC 109...	2.0E-98	[1..423]	[1..423]
gi\|56961794, gi\|... - gi\|56961794\|ref\|YP_173516.1\| D-alanyl-D-alanine carboxypeptidase [Bacillus clausii KSM-K16], gi\|5690...	5.0E-95	[9..422]	[2..420]
gi\|116052037, gi... - gi\|116052037\|ref\|YP_789120.1\| D-ala-D-ala-carboxypeptidase [Pseudomonas aeruginosa UCBPP-PA14], gi\|1... gi\|126196061, gi... - gi\|254242683\|ref\|ZP_04936005.1\| D-ala-D-ala-carboxypeptidase [Pseudomonas aeruginosa 2192], gi\|19455... gi\|194547876, gi... - gi\|254236891\|ref\|ZP_04930214.1\| D-ala-D-ala-carboxypeptidase [Pseudomonas aeruginosa C3719], gi\|1945... gi\|11348401, gi\|... - gi\|4887207\|gb\|AAD32234.1\|AF147448_5 penicillin-binding protein 5 [Pseudomonas aeruginosa], pir\|\|C831... gi\|9950191, gi\|1... - gi\|9950191\|gb\|AAG07386.1\|AE004817_10 D-ala-D-ala-carboxypeptidase [Pseudomonas aeruginosa PAO1], gi\|... gi\|218769943, gi... - gi\|218889720\|ref\|YP_002438584.1\| D-ala-D-ala-carboxypeptidase [Pseudomonas aeruginosa LESB58], gi\|21...	6.0E-95	[5..420]	[9..386]
gi\|15612584, gi\|... - gi\|15612584\|ref\|NP_240887.1\| serine-type D-Ala-D-Ala carboxypeptidase [Bacillus halodurans C-125], g... gi\|25297777 - pir\|\|E83652 serine-type D-Ala-D-Ala carboxypeptidase dacA [imported] - Bacillus halodurans (strain C...	7.0E-95	[2..420]	[6..433]
gi\|220706073, gi... - gi\|221090010\|ref\|ZP_03559506.1\| Serine-type D-Ala-D-Ala carboxypeptidase [Geobacillus sp. Y412MC61],... gi\|229328468, gi... - gi\|229500653\|ref\|ZP_04394305.1\| Serine-type D-Ala-D-Ala carboxypeptidase [Geobacillus sp. Y412MC52],... DACA_GEOSE - D-alanyl-D-alanine carboxypeptidase DacA OS=Geobacillus stearothermophilus GN=dacA PE=1 SV=1 gi\|56418545, gi\|... - gi\|56418545\|ref\|YP_145863.1\| serine-type D-Ala-D-Ala carboxypeptidase [Geobacillus kaustophilus HTA4...	2.0E-94	[1..422]	[1..444]
gi\|119946648, gi... - gi\|119946648\|ref\|YP_944328.1\| Serine-type D-Ala-D-Ala carboxypeptidase [Psychromonas ingrahamii 37],...	3.0E-94	[1..420]	[16..406]
gi\|148549880, gi... - gi\|82738224\|ref\|ZP_00901061.1\| D-alanyl-D-alanine carboxypeptidase [Pseudomonas putida F1], gi\|82714...	7.0E-94	[5..420]	[26..403]
gi\|89203315, gi\|... - gi\|89203315\|ref\|ZP_01181996.1\| Serine-type D-Ala-D-Ala carboxypeptidase [Bacillus cereus subsp. cyto...	2.0E-93	[2..421]	[7..430]
gi\|24986562, gi\|... - gi\|26991483\|ref\|NP_746908.1\| Serine-type D-Ala-D-Ala carboxypeptidase [Pseudomonas putida KT2440], g...	2.0E-93	[5..420]	[9..386]

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Predicted Domain #1

Region A:
Residues: [1-423]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKILSILLA LLLSISSLGV TTSHAEEKIH IEAAAALLFD ADTGKILHEQ NPDELLAIAS  60
   61 MSKLIVVYAV LEAIKEGKIT WDTKVNISDY AYEVSRNNEF SNVPFEKGRQ YTVRELYHSI 120
  121 VIFSANGSSI ALAELLAGSE KNFLNLANEH AKKLGLKKYK FVNATGLNNT DLKGKHPEGT 180
  181 DPNAENSMSA RDMGILSKAM ITKYPEMLED TKQRFRNFPD NHPKPIRMEN WNWMLPGAAF 240
  241 AYEGTDGLKT GSSDTAGYGF TITAKRGDVR LISVIIKTKS MDERFTESRE LIEYGFNNFE 300
  301 KQKLKVDKNN TLSVAQGKED QVTVAPEKEI TVIAKKGSKN PYKIGTEVDK SLAEDGHLVA 360
  361 PIKKDAKVGS ITLESTDKYG FLDGSNSMKV TAKTTEEVEK ANWFVLTMRS IGDFFSNLWS 420
  421 KVF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.522879
Match:	1xp4A
Description:	Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
drug binding	3.43867028493374	bayes_pls_golite062009
peptidase activity	3.14503902416546	bayes_pls_golite062009
serine-type D-Ala-D-Ala carboxypeptidase activity	3.12650314537616	bayes_pls_golite062009
penicillin binding	2.89507018520983	bayes_pls_golite062009
hydrolase activity	2.80171403488139	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.78480589579188	bayes_pls_golite062009
serine-type carboxypeptidase activity	2.70174066798582	bayes_pls_golite062009
serine-type exopeptidase activity	2.69091897402517	bayes_pls_golite062009
carboxypeptidase activity	1.96547160092829	bayes_pls_golite062009
catalytic activity	1.85492008367309	bayes_pls_golite062009
serine hydrolase activity	1.69122379434116	bayes_pls_golite062009
serine-type peptidase activity	1.6885532900392	bayes_pls_golite062009
exopeptidase activity	1.24775184094433	bayes_pls_golite062009
binding	1.11566650386305	bayes_pls_golite062009
protein binding	0.0666688846338231	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: