YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258533, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	1072 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258533, gi|....

Description	E-value	Query Range	Subject Range
CARB_BACHK - Carbamoyl-phosphate synthase large chain OS=Bacillus thuringiensis subsp. konkukian GN=carB PE=3 SV=... CARB_BACHK - Carbamoyl-phosphate synthase large chain OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) G...	0.0	[1..1072]	[1..1072]
CARB_BACC1 - Carbamoyl-phosphate synthase large chain OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=carB PE...	0.0	[1..1072]	[1..1072]
CARB_BACCZ - Carbamoyl-phosphate synthase large chain OS=Bacillus cereus (strain ZK / E33L) GN=carB PE=3 SV=1	0.0	[1..1072]	[1..1072]
CARB_BACCR - Carbamoyl-phosphate synthase large chain OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 /...	0.0	[1..1072]	[1..1072]
gi\|47553843, gi\|... - gi\|47569514\|ref\|ZP_00240194.1\| carbamoyl-phosphate synthase, large subunit [Bacillus cereus G9241], ...	0.0	[1..1072]	[1..1072]
CARB_BACWK - Carbamoyl-phosphate synthase large chain OS=Bacillus weihenstephanensis (strain KBAB4) GN=carB PE=3 ...	0.0	[1..1072]	[1..1072]
CARB_BACCN - Carbamoyl-phosphate synthase large chain OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 39...	0.0	[1..1072]	[1..1072]
CARB_PASMU - Carbamoyl-phosphate synthase large chain OS=Pasteurella multocida (strain Pm70) GN=carB PE=3 SV=1 CARB_PASMU - Carbamoyl-phosphate synthase large chain OS=Pasteurella multocida GN=carB PE=3 SV=1	0.0	[1..1065]	[1..1067]
gi\|56379529, gi\|... - gi\|56419687\|ref\|YP_147005.1\| carbamoyl phosphate synthase large subunit [Geobacillus kaustophilus HT...	0.0	[1..1060]	[1..1060]
gi\|11272706 - pir\|\|D81035 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) large chain NMB1855 [s... CARB_NEIMB - Carbamoyl-phosphate synthase large chain OS=Neisseria meningitidis serogroup B (strain MC58) GN=carB... CARB_NEIMB - Carbamoyl-phosphate synthase large chain OS=Neisseria meningitidis serogroup B GN=carB PE=3 SV=1	0.0	[1..1068]	[1..1070]

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Predicted Domain #1

Region A:
Residues: [1-1072]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRLDINTI LVIGSGPIVI GQAAEFDYSG TQACQSLKEE GYKVILVNSN PATIMTDTAT  60
   61 ADKVYIEPLT LEFVSRIIRK ERPDAILPTL GGQTGLNMAV ELAKSGVLEE CGVEILGTKL 120
  121 SAIEQAEDRD LFRTLMQELN EPTPPSEIIH NLDEAYGFVN EIGYPVIVRP AFTLGGTGGG 180
  181 ICHNEEELIE IVTSGLKHSP VTQCLLEKSI AGCKEIEYEV MRDSNDNAIV VCNMENIDPV 240
  241 GVHTGDSIVV APSQTLSDRE YQMLRNTSLR IIRALGIEGG CNVQLALDPY SFQYYVIEVN 300
  301 PRVSRSSALA SKATGYPIAK LAAKIAVGLT LDEIVNPVTQ KTYACFEPAL DYVVSKIPRW 360
  361 PFDKFESANR TLGTQMKATG EVMSIGRNLE ESLLKAVRSL ELGIYHLELD HLKELDKETM 420
  421 KKRIIKADDE RLFIVAEAIR QGVTKEEINE WCEMDFFFLQ KVENIVNMER EVKANVGNME 480
  481 VLQTAKEMGF SDHYIAAAWN KTEREIYDMR KENNMTPVFK MVDTCAAEFE SATPYYYSTY 540
  541 ADENELIVTD RKSVVVLGSG PIRIGQGVEF DYATVHSVWA IKEAGYEAII INNNPETVST 600
  601 DFSISDKLYF EPLTIEDVMH IIDLEKPEGV IVQFGGQTAI NLAAKLEEHG VKILGTSLED 660
  661 LDRAEDRDKF EAALTKLGIP QPVGKTATTV EQAVAIAEEI GYPVLVRPSY VLGGRAMEIV 720
  721 YRQEELLHYM KNAVKVHADH PVLIDRYMVG KEIEVDAISD GENVFIPGIM EHIERAGVHS 780
  781 GDSIGVYPPQ SLSEKLKEQI IEHTIALGKG LNIVGLLNIQ FVVFKDQVYV IEVNPRASRT 840
  841 VPFLSKITGV PMANVATKVI LGQDLVEQGY GTGYHPEEKE VYVKAPVFSF AKLRSVDTTL 900
  901 GPEMKSTGEV MGKDLTLEKA LYKGLVASGI NIPTHGSVII TVADKDKEEA MEIAKRFHEI 960
  961 GYNLLATAGT AQSLTEQNIP VQVVNKIDSE DYNLLDIIRQ GKAQFVINTL TKGKQPARDG1020
 1021 FRIRRESVEN GVACLTSLDT TRAILRVLES MTFSAHSMKE ITQTKRHEVV HA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1bxrA
Description:	Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbamoyl-phosphate synthase activity	10.3961907577933	bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	10.3817460390594	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	7.55690629692775	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	6.95559501787172	bayes_pls_golite062009
ligase activity	1.91091941710895	bayes_pls_golite062009
phosphoribosylaminoimidazole carboxylase activity	1.57708889650281	bayes_pls_golite062009
catalytic activity	1.08688404807699	bayes_pls_golite062009
phosphoribosylamine-glycine ligase activity	1.04915286326924	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	0.964679554894316	bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity	0.898425265043358	bayes_pls_golite062009
acid-amino acid ligase activity	0.730894973410499	bayes_pls_golite062009
carbon-oxygen lyase activity	0.482425669839603	bayes_pls_golite062009
lyase activity	0.432948879967458	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	0.37779550230552	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	0.2431211195117	bayes_pls_golite062009
glutathione synthase activity	0.0685848191991462	bayes_pls_golite062009
biotin carboxylase activity	0.0172732430077291	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: