YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258455, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	712 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258455, gi|....

Description	E-value	Query Range	Subject Range
PNP_BACLD - Polyribonucleotide nucleotidyltransferase OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JC...	0.0	[1..705]	[1..705]
gi\|25311841, gi\|... - pir\|\|AE2586 polyribonucleotide nucleotidyltransferase pnpA [imported] - Agrobacterium tumefaciens (s... PNP_AGRFC - Polyribonucleotide nucleotidyltransferase OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=pnp P...	0.0	[3..709]	[2..709]
PNP_RHIL3 - Polyribonucleotide nucleotidyltransferase OS=Rhizobium leguminosarum bv. viciae (strain 3841) GN=pnp...	0.0	[3..709]	[2..709]
PNP_BACSU - Polyribonucleotide nucleotidyltransferase OS=Bacillus subtilis GN=pnp PE=1 SV=3 gi\|221313871 - gi\|221313871\|ref\|ZP_03595676.1\| polynucleotide phosphorylase/polyadenylase [Bacillus subtilis subsp.... gi\|221318794 - gi\|221318794\|ref\|ZP_03600088.1\| polynucleotide phosphorylase/polyadenylase [Bacillus subtilis subsp.... gi\|221323066 - gi\|221323066\|ref\|ZP_03604360.1\| polynucleotide phosphorylase/polyadenylase [Bacillus subtilis subsp.... PNP_BACSU - Polyribonucleotide nucleotidyltransferase OS=Bacillus subtilis (strain 168) GN=pnp PE=1 SV=3	0.0	[1..695]	[1..695]
PNP_BACCR - Polyribonucleotide nucleotidyltransferase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 ...	0.0	[1..712]	[1..712]
PNP_METFK - Polyribonucleotide nucleotidyltransferase OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / D...	0.0	[5..708]	[3..707]
PNP_RHILO - Polyribonucleotide nucleotidyltransferase OS=Rhizobium loti (strain MAFF303099) GN=pnp PE=3 SV=1 PNP_RHILO - Polyribonucleotide nucleotidyltransferase OS=Rhizobium loti GN=pnp PE=3 SV=1	0.0	[3..711]	[2..712]
PNP_BACHK - Polyribonucleotide nucleotidyltransferase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) ... PNP_BACAH - Polyribonucleotide nucleotidyltransferase OS=Bacillus thuringiensis (strain Al Hakam) GN=pnp PE=3 SV... PNP_BACHK - Polyribonucleotide nucleotidyltransferase OS=Bacillus thuringiensis subsp. konkukian GN=pnp PE=3 SV=... PNP_BACCZ - Polyribonucleotide nucleotidyltransferase OS=Bacillus cereus (strain ZK / E33L) GN=pnp PE=3 SV=1 gi\|47569084, gi\|... - gi\|47569084\|ref\|ZP_00239773.1\| polyribonucleotide nucleotidyltransferase [Bacillus cereus G9241], gi... gi\|228928856, gi... - gi\|228928856\|ref\|ZP_04091888.1\| Polyribonucleotide nucleotidyltransferase [Bacillus thuringiensis se... PNP_BACAC - Polyribonucleotide nucleotidyltransferase OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN=pnp ... gi\|228772728, gi... - gi\|228986950\|ref\|ZP_04147076.1\| Polyribonucleotide nucleotidyltransferase [Bacillus thuringiensis se... gi\|228824487, gi... - gi\|228935122\|ref\|ZP_04097949.1\| Polyribonucleotide nucleotidyltransferase [Bacillus thuringiensis se... gi\|229123320, gi... - gi\|229123320\|ref\|ZP_04252524.1\| Polyribonucleotide nucleotidyltransferase [Bacillus cereus 95/8201],... gi\|228690470, gi... - gi\|229092848\|ref\|ZP_04223982.1\| Polyribonucleotide nucleotidyltransferase [Bacillus cereus Rock3-42]... gi\|228597463, gi... - gi\|229186044\|ref\|ZP_04313214.1\| Polyribonucleotide nucleotidyltransferase [Bacillus cereus BGSC 6E1]... gi\|228626111, gi... - gi\|229157384\|ref\|ZP_04285462.1\| Polyribonucleotide nucleotidyltransferase [Bacillus cereus ATCC 4342... gi\|254735845 - gi\|254735845\|ref\|ZP_05193551.1\| polynucleotide phosphorylase/polyadenylase [Bacillus anthracis str. ... gi\|254683486 - gi\|254683486\|ref\|ZP_05147346.1\| polynucleotide phosphorylase/polyadenylase [Bacillus anthracis str. ... gi\|254755998 - gi\|254755998\|ref\|ZP_05208029.1\| polynucleotide phosphorylase/polyadenylase [Bacillus anthracis str. ... gi\|254739629 - gi\|254739629\|ref\|ZP_05197323.1\| polynucleotide phosphorylase/polyadenylase [Bacillus anthracis str. ... gi\|167512267, gi... - gi\|167639866\|ref\|ZP_02398135.1\| polyribonucleotide nucleotidyltransferase [Bacillus anthracis str. A... gi\|170668150, gi... - gi\|170687834\|ref\|ZP_02879048.1\| polyribonucleotide nucleotidyltransferase [Bacillus anthracis str. A... gi\|165872621, gi... - gi\|165872621\|ref\|ZP_02217252.1\| polyribonucleotide nucleotidyltransferase [Bacillus anthracis str. A... gi\|167635853, gi... - gi\|167635853\|ref\|ZP_02394162.1\| polyribonucleotide nucleotidyltransferase [Bacillus anthracis str. A... gi\|196042164, gi... - gi\|196042164\|ref\|ZP_03109447.1\| polyribonucleotide nucleotidyltransferase [Bacillus cereus NVH0597-9... gi\|196024617, gi... - gi\|196044582\|ref\|ZP_03111817.1\| polyribonucleotide nucleotidyltransferase [Bacillus cereus 03BB108],... gi\|177652128, gi... - gi\|177652128\|ref\|ZP_02934674.1\| polyribonucleotide nucleotidyltransferase [Bacillus anthracis str. A... gi\|190568447, gi... - gi\|190568447\|ref\|ZP_03021354.1\| polyribonucleotide nucleotidyltransferase [Bacillus anthracis Tsiank...	0.0	[1..712]	[1..712]
PNP_BACC1 - Polyribonucleotide nucleotidyltransferase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=pnp PE...	0.0	[1..712]	[1..712]
gi\|606104 - gi\|606104\|gb\|AAA57967.1\| polynucleotide phosphorylase [Escherichia coli] gi\|49176320, gi\|... - gi\|49176320\|ref\|NP_417633.3\| polynucleotide phosphorylase/polyadenylase [Escherichia coli K12], gi\|1... gi\|170082701, gi... - gi\|170082701\|ref\|YP_001732021.1\| polynucleotide phosphorylase/polyadenylase [Escherichia coli str. K... gi\|242378709, gi... - gi\|251786436\|ref\|YP_003000740.1\| hypothetical protein B21_02982 [Escherichia coli BL21], gi\|24237870... gi\|606104\|gb\|AAA... - polynucleotide phosphorylase [Escherichia coli] gi\|253979165, gi... - gi\|254289858\|ref\|YP_003055606.1\| polynucleotide phosphorylase/polyadenylase [Escherichia coli BL21(D... gi\|254163108, gi... - gi\|254163108\|ref\|YP_003046216.1\| polynucleotide phosphorylase/polyadenylase [Escherichia coli B str.... gi\|89109929, gi\|... - gi\|89109929\|ref\|AP_003709.1\| polynucleotide phosphorylase/polyadenylase [Escherichia coli str. K-12 ...	0.0	[3..696]	[25..718]

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Predicted Domain #1

Region A:
Residues: [1-712]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEKQVFSI DLAGRQLTVE TGQLAKQANG AVLVRYGDTA VLSTATASKE AKNVDFFPLT  60
   61 VNYEERLYAV GKIPGGFIKR EGRPSEKAIL ASRLIDRPIR PLFADGFRNE VQVVNIVMSV 120
  121 DQDCSSEMAA MLGSSLALSI SDIPFEGPIA GATVGRINGE FVINPTVEQQ EQSDIHLVVA 180
  181 GTKDAINMVE AGADQVPEET MLEAIMFGHD EIKRLIAFQE EIVQAVGKEK SEVKLYEVDA 240
  241 DLNQAVREMA EKDMHSAIQV HEKHAREDAI NEVKKRVIEH YEAQEADADT LGQVNEILYK 300
  301 IVKEEVRRLI TVEKIRPDGR KGDEIRPLAS EVGILSRTHG SGLFTRGQTQ ALSICTLGAL 360
  361 GDVQILDGLG VEESKRFMHH YNFPSFSVGE TRPMRGPGRR EIGHGALGER ALEPVIPSEK 420
  421 DFPYTVRLVS EVLESNGSTS QASICGSTLA MMDAGVPLKA PVAGIAMGLV KTGEHYTILS 480
  481 DIQGMEDHLG DMDFKVAGTA HGVTALQMDI KIDGLSREIL EEALQQAKVG RVHILNHMLS 540
  541 VIAEPRTELS AYAPKIITMT INPDKIRDVI GPSGKQINKI IEETGVKIDI EQDGTVFISS 600
  601 INQEMNDKAK KIIEDIVREV QVGEIYEGKV KRVEKFGAFV ELFSGKDGLV HISELALERV 660
  661 GKVEDVVKIG DVITVKVIEI DKQGRVNLSR KVLLKEEQEK EAAKEENKQE QQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	146.0
Match:	1e3hA
Description:	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
exoribonuclease activity	7.55877202113513	bayes_pls_golite062009
ribonuclease activity	7.54644729272203	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	7.5310318714913	bayes_pls_golite062009
3'-5'-exoribonuclease activity	6.46930372693262	bayes_pls_golite062009
3'-5' exonuclease activity	4.29895100594643	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3.83939403332553	bayes_pls_golite062009
exonuclease activity	3.40686901061667	bayes_pls_golite062009
transcription regulator activity	3.24341202600661	bayes_pls_golite062009
RNA binding	2.47373172667773	bayes_pls_golite062009
structural constituent of ribosome	2.13956481798878	bayes_pls_golite062009
structural molecule activity	1.95031459523051	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.71222144385878	bayes_pls_golite062009
nucleic acid binding	1.45130233071198	bayes_pls_golite062009
binding	1.38311294671926	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	1.35850109411274	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	1.35845277283398	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	1.35845277283398	bayes_pls_golite062009
	1.2099360907571	bayes_pls_golite062009
exoribonuclease II activity	1.18248519339188	bayes_pls_golite062009
transcription termination factor activity	1.01993495617192	bayes_pls_golite062009
DNA binding	1.01454217691792	bayes_pls_golite062009
hydrolase activity	0.722411371082264	bayes_pls_golite062009
ATP-dependent peptidase activity	0.66778558090199	bayes_pls_golite062009
carbohydrate kinase activity	0.51810239718467	bayes_pls_golite062009
mRNA binding	0.403794675006504	bayes_pls_golite062009
tRNA-specific ribonuclease activity	0.383567539949931	bayes_pls_golite062009
ligase activity	0.346041081217685	bayes_pls_golite062009
transcription factor activity	0.298729064067577	bayes_pls_golite062009
protein binding	0.292595239533272	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.151650064901878	bayes_pls_golite062009
translation initiation factor activity	0.11625379846973	bayes_pls_golite062009
catalytic activity	0.10089766806364	bayes_pls_golite062009
DNA-directed RNA polymerase activity	0.0740938021136293	bayes_pls_golite062009
RNA polymerase activity	0.0740938021136293	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0287026367466632	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: