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View Structure Prediction Details

Protein: gi|30257267, gi|...
Organism: Bacillus anthracis str. Ames
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257267, gi|....

Description E-value Query
Range
Subject
Range
gi|3395665 - gi|3395665|dbj|BAA32077.1| ampC [Enterobacter cloacae]
1.0E-74 [2..340] [27..374]
gi|22213623 - gi|22213623|gb|AAM93471.1| beta-lactamase; AmpC [Citrobacter freundii]
3.0E-74 [2..333] [27..370]
gi|20136434 - gi|20136434|gb|AAM11664.1|AF492445_2 AmpC [Citrobacter murliniae]
6.0E-74 [2..335] [27..372]
gi|2959390 - gi|2959390|emb|CAA76382.1| beta-lactamase class C [Proteus mirabilis]
8.0E-74 [2..338] [27..378]
gi|21213049 - gi|21213049|emb|CAD32299.1| beta-lactamase precursor [Enterobacter nimipressuralis]
1.0E-73 [2..339] [31..383]

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Predicted Domain #1
Region A:
Residues: [1-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTKDQIDNI VKETYRHIDF SGVILVKEKK GIVYEEVFGY ANRNECINNT LQTRFGIASG  60
   61 CKIFTAIGIC QLVENGVITF QTKLKECLSV NFPNFNEDIT IHHLLTHSSG IPDYFDESIM 120
  121 DNFEDLWKQT PMYLLKSLKD FLPLFQNRDM MYAPGSKFHY NNAGFIILGL IIEEQTGLTF 180
  181 TEYIEKNIFN PIGMNHSGYF SLDRLPRQTA LGYIKDEISQ TWRTNAYSIP IKGGSDGGAF 240
  241 ITASDMLKFW EALFNYEIIS QEYTKILLTP HIQVNNNQSY GYGIWIETRE NKIFKYHVMG 300
  301 YDPGVSFRSA VYPDLGITLV IPSNKGAGAE KLMIEIEGSF 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.30103
Match: 1rgyA
Description: Citrobacter freundii GN346 Class C beta-Lactamase Complexed with Transition-State Analog of Cefotaxime
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
serine-type D-Ala-D-Ala carboxypeptidase activity 3.12650314537616 bayes_pls_golite062009
penicillin binding 2.89507018520983 bayes_pls_golite062009
serine-type carboxypeptidase activity 2.70174066798582 bayes_pls_golite062009
serine-type exopeptidase activity 2.69091897402517 bayes_pls_golite062009
drug binding 2.17649666461595 bayes_pls_golite062009
carboxypeptidase activity 1.96547160092829 bayes_pls_golite062009
catalytic activity 1.85492008367309 bayes_pls_golite062009
exopeptidase activity 1.44522375970439 bayes_pls_golite062009
binding 0.183081253999081 bayes_pls_golite062009
peptidase activity 0.0617672513497823 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle