YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30253959, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	459 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30253959, gi|....

Description	E-value	Query Range	Subject Range
gi\|228751341, gi... - gi\|229009910\|ref\|ZP_04167129.1\| Uncharacterized RNA methyltransferase [Bacillus mycoides DSM 2048], ... gi\|163938416, gi... - gi\|89204676\|ref\|ZP_01183252.1\| 23S rRNA methyltransferase/RumA [Bacillus weihenstephanensis KBAB4], ... gi\|228652007, gi... - gi\|229131423\|ref\|ZP_04260319.1\| Uncharacterized RNA methyltransferase [Bacillus cereus BDRD-ST196], ...	0.0	[1..459]	[1..459]
gi\|228726986, gi... - gi\|229042327\|ref\|ZP_04190077.1\| Uncharacterized RNA methyltransferase [Bacillus cereus AH676], gi\|22... gi\|228913174, gi... - gi\|228913174\|ref\|ZP_04076813.1\| Uncharacterized RNA methyltransferase [Bacillus thuringiensis serova... gi\|47556095, gi\|... - gi\|47567252\|ref\|ZP_00237966.1\| RNA methyltransferase, TrmA family [Bacillus cereus G9241], gi\|475560...	0.0	[1..459]	[1..459]
gi\|196023809, gi... - gi\|196045225\|ref\|ZP_03112457.1\| 23S rRNA (uracil-5-)-methyltransferase RumA [Bacillus cereus 03BB108... gi\|229182811, gi... - gi\|229182811\|ref\|ZP_04310050.1\| Uncharacterized RNA methyltransferase [Bacillus cereus BGSC 6E1], gi... gi\|229194804, gi... - gi\|229194804\|ref\|ZP_04321591.1\| Uncharacterized RNA methyltransferase [Bacillus cereus m1293], gi\|22... gi\|118476178, gi... - gi\|118476178\|ref\|YP_893329.1\| tRNA (uracil-5-)-methyltransferase [Bacillus thuringiensis str. Al Hak... Y542_BACC1 - Uncharacterized RNA methyltransferase BCE_0542 OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=B... gi\|225862467, gi... - gi\|225862467\|ref\|YP_002747845.1\| 23S rRNA (uracil-5-)-methyltransferase RumA [Bacillus cereus 03BB10...	0.0	[1..459]	[1..459]
Y687_BACHD - Uncharacterized RNA methyltransferase BH0687 OS=Bacillus halodurans GN=BH0687 PE=3 SV=1 Y687_BACHD - Uncharacterized RNA methyltransferase BH0687 OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197...	0.0	[4..459]	[2..457]
gi\|196040108, gi... - gi\|196040108\|ref\|ZP_03107410.1\| 23S rRNA (uracil-5-)-methyltransferase RumA [Bacillus cereus NVH0597... gi\|195992765, gi... - gi\|196034722\|ref\|ZP_03102130.1\| 23S rRNA (uracil-5-)-methyltransferase RumA [Bacillus cereus W], gi\|... gi\|49328374, gi\|... - gi\|49476818\|ref\|YP_034754.1\| tRNA (uracil-5-)-methyltransferase [Bacillus thuringiensis serovar konk... gi\|51978290, gi\|... - gi\|52144821\|ref\|YP_082009.1\| RNA methyltransferase [Bacillus cereus E33L], gi\|51978290\|gb\|AAU19840.1... gi\|228833955, gi... - gi\|228925680\|ref\|ZP_04088767.1\| Uncharacterized RNA methyltransferase [Bacillus thuringiensis serova... gi\|228640293, gi... - gi\|229143212\|ref\|ZP_04271644.1\| Uncharacterized RNA methyltransferase [Bacillus cereus BDRD-ST24], g... gi\|228663326, gi... - gi\|229120088\|ref\|ZP_04249340.1\| Uncharacterized RNA methyltransferase [Bacillus cereus 95/8201], gi\|... gi\|228956903, gi... - gi\|228956903\|ref\|ZP_04118684.1\| Uncharacterized RNA methyltransferase [Bacillus thuringiensis serova... gi\|228815391, gi... - gi\|228944240\|ref\|ZP_04106616.1\| Uncharacterized RNA methyltransferase [Bacillus thuringiensis serova... gi\|218901630, gi... - gi\|218901630\|ref\|YP_002449464.1\| 23S rRNA (uracil-5-)-methyltransferase RumA [Bacillus cereus AH820]... gi\|218159316, gi... - gi\|218231359\|ref\|YP_002365269.1\| 23S rRNA (uracil-5-)-methyltransferase RumA [Bacillus cereus B4264]...	0.0	[1..459]	[1..459]
gi\|52784541, gi\|... - gi\|52784541\|ref\|YP_090370.1\| YefA [Bacillus licheniformis ATCC 14580], gi\|52347043\|gb\|AAU39677.1\| Ye...	0.0	[5..459]	[2..458]
gi\|51978385, gi\|... - gi\|52144916\|ref\|YP_081914.1\| RNA methyltransferase [Bacillus cereus E33L], gi\|51978385\|gb\|AAU19935.1...	0.0	[2..456]	[1..455]
Y364_BACCR - Uncharacterized RNA methyltransferase BC_0364 OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2...	0.0	[2..456]	[1..455]

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Predicted Domain #1

Region A:
Residues: [1-459]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQKQHESKL EVGQTFPVTI KRLGINGEGV GYFKRQVVFI PGALPGEEVV AETTKIQRGF  60
   61 AEAKVKKVRK ASPHRVKAPC PVYEECGGCQ LQHLDYKEQL NQKRDIVVQA FEKYMKNSME 120
  121 EKIRPTLGME NPWHYRNKSQ LQVGRKDEKV ITGLYKQNSH QLIDIAHCMI QHKATNEATK 180
  181 VVRRILEKLN VSIYNEKKQK GLVRTIVTRT AVQTGEVQVT LITTKEELPN KEQFIAEVQK 240
  241 QMPAVKSIMQ NVNWRKTSVI FGDKTFKLAG KEVIQETLGD LSFELSARAF FQLNPEQTVV 300
  301 LYNEAKKAAA LTGNEKIVDA YCGVGTIGLW LANDAAEVRG MDVIPEAIAD ARKNAKRHGF 360
  361 TNTKYEAGKA EQWLPKWVKE GWRPDVIVVD PPRTGCDDKL LETILKVKPK QVVYVSCNPS 420
  421 SLARDVQALM KSYEVEYVQP VDMFPHTAHV ENVVKLTLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.045757
Match:	1uwvA
Description:	Crystal Structure of RumA, the iron-sulfur cluster containing E. coli 23S Ribosomal RNA 5-Methyluridine Methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
N-methyltransferase activity	4.07806017452628	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
protein methyltransferase activity	3.92746815303714	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
histone methyltransferase activity	2.99461585647365	bayes_pls_golite062009
tRNA methyltransferase activity	2.5931020126592	bayes_pls_golite062009
arginine N-methyltransferase activity	2.41876112831625	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	2.41876112831625	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
DNA-methyltransferase activity	2.18991764495147	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	2.04350689362549	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	2.04350689362549	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	2.04296107639729	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	2.04218282227834	bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity	1.88889414729709	bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity	1.88889414729709	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.66871163498737	bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity	1.29759910099835	bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity	1.29759910099835	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	1.1103522853299	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	1.10713374933008	bayes_pls_golite062009
ligase activity	1.06979791212194	bayes_pls_golite062009
single-stranded DNA binding	0.97496043954059	bayes_pls_golite062009
structural constituent of ribosome	0.943661008731946	bayes_pls_golite062009
transcription regulator activity	0.914549843668268	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.89325812193225	bayes_pls_golite062009
DNA binding	0.86027591375666	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
ribonuclease activity	0.702449673647117	bayes_pls_golite062009
nucleic acid binding	0.616949327277483	bayes_pls_golite062009
structural molecule activity	0.596857566298868	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.504302440847948	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.449277083957511	bayes_pls_golite062009
RNA binding	0.417524996559564	bayes_pls_golite062009
exoribonuclease activity	0.40223812695012	bayes_pls_golite062009
binding	0.383237930789959	bayes_pls_golite062009
sequence-specific DNA binding	0.32084431704638	bayes_pls_golite062009
transcription factor activity	0.298729064067577	bayes_pls_golite062009
O-methyltransferase activity	0.250946859465502	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	0.234572322347698	bayes_pls_golite062009
translation regulator activity	0.22908707234671	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	0.203168546434167	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.179682348023561	bayes_pls_golite062009
3'-5'-exoribonuclease activity	0.13299060447839	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: