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View Structure Prediction Details

Protein: gi|24376049, gi|...
Organism: Shewanella oneidensis MR-1
Length: 464 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24376049, gi|....

Description E-value Query
Range
Subject
Range
gi|75701558, gi|... - gi|75907833|ref|YP_322129.1| amino acid adenylation [Anabaena variabilis ATCC 29413], gi|75701558|gb...
434.0 [0..5] [464..549]
gi|49610951, gi|... - gi|50120425|ref|YP_049592.1| non-ribosomal peptide synthetase [Pectobacterium atrosepticum SCRI1043]...
430.0 [0..5] [462..5913]
gi|27817222 - gi|27817222|gb|AAO23333.1| NcpA [Nostoc sp. ATCC 53789]
424.0 [0..5] [463..2671]
gi|17131741, gi|... - gi|17230140|ref|NP_486688.1| peptide synthetase [Nostoc sp. PCC 7120], gi|17131741|dbj|BAB74347.1| p...
gi|25294032 - pir||AI2136 peptide synthetase [imported] - Nostoc sp. (strain PCC 7120)
422.0 [0..5] [462..465]
LGRC_BREPA - Linear gramicidin synthase subunit C OS=Brevibacillus parabrevis GN=lgrC PE=3 SV=1
gi|42820780 - gi|42820780|emb|CAD92851.1| nonribosomal peptide synthetase [Brevibacillus brevis]
420.0 [0..6] [462..5648]
gi|186682529, gi... - gi|23129063|ref|ZP_00110897.1| COG1020: Non-ribosomal peptide synthetase modules and related protein...
418.0 [0..5] [464..1574]
gi|9715733 - gi|9715733|emb|CAC01603.1| peptide synthetase [Anabaena circinalis 90]
417.0 [0..5] [464..583]

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Predicted Domain #1
Region A:
Residues: [1-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRISPLHSAA LTFPEQTAVK CNGQDISYAS LSQMVLGLGE QLTRIGIRQG QPLACISRNN  60
   61 LEMICLYWAC IDIGAIFFPI SPRFPLAQVQ GLIDSHQIPC YWSETELGLT GCTQLSLDVA 120
  121 QISTTPAKTV DIQRPCNVIL TSGSSGFPKA AVHNLANHIA NAEGARSLIP LIKGDAWLLS 180
  181 LPLFHIGGLA ILNRCALVAA IVVLPESNLA LQEQVERDAL THISLVPTQL LNLLADKQAS 240
  241 LTSIKALLLG GGAVSIDLLK QLEQRHIASF TSYGMTEMGS QITTGPALSD GTSGKLLPRR 300
  301 ELKIVDDVIW VRGECLFMGY LTENGIEKPL DADSWFYTKD KGEWDANGNL KILGRVDNMF 360
  361 ICGGENIQPE EIEAALKLHP LIDEAIVFPQ PDITYGQLPA AIIRGNIIRG NTSQDMSTIE 420
  421 KQLEQFLADK IARFKRPRRY YPWPENAEQI GLKVNRQLII KLAI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.0
Match: 1amuA
Description: Phenylalanine activating domain of gramicidin synthetase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds 4.4819902512335 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 2.89129353633634 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
CoA-ligase activity 2.5960476232329 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
transcription regulator activity 2.31193176808353 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 1.5312519256537 bayes_pls_golite062009
transcription repressor activity 1.2638869228049 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle