YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24347949, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	379 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24347949, gi|....

Description	E-value	Query Range	Subject Range
gi\|160861160, gi... - gi\|160875638\|ref\|YP_001554954.1\| S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydr... gi\|68542288, gi\|... - gi\|68542288\|ref\|ZP_00582021.1\| Zinc-containing alcohol dehydrogenase superfamily [Shewanella baltica... gi\|77816052, gi\|... - gi\|77816052\|ref\|ZP_00815261.1\| Zinc-containing alcohol dehydrogenase superfamily [Shewanella putrefa... gi\|153000927, gi... - gi\|153000927\|ref\|YP_001366608.1\| S-(hydroxymethyl)glutathione dehydrogenase [Shewanella baltica OS18... gi\|146863790, gi... - gi\|217973117\|ref\|YP_002357868.1\| S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydr...	419.0	[0..1]	[379..1]
gi\|113884808, gi... - gi\|82496301\|ref\|ZP_00881870.1\| alcohol dehydrogenase class III [Shewanella sp. MR-4], gi\|82405657\|gb... gi\|78685011, gi\|... - gi\|78685011\|ref\|ZP_00849792.1\| alcohol dehydrogenase class III [Shewanella sp. ANA-3], gi\|78507235\|g... gi\|78510849, gi\|... - gi\|78689689\|ref\|ZP_00854347.1\| alcohol dehydrogenase class III [Shewanella sp. MR-7], gi\|78510849\|gb...	418.0	[0..1]	[379..1]
gi\|238715026, gi... - gi\|77958654\|ref\|ZP_00822684.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia ber...	413.0	[0..7]	[379..2]
gi\|157278309, gi... - gi\|42412381\|gb\|AAS15570.1\| class III alcohol dehydrogenase [Oryzias latipes], gi\|157278309\|ref\|NP_00...	412.0	[0..3]	[377..2]
gi\|54308673, gi\|... - gi\|54308673\|ref\|YP_129693.1\| putative alcohol dehydrogenase class III [Photobacterium profundum SS9]...	412.0	[0..7]	[379..4]
gi\|90325090, gi\|... - gi\|90413906\|ref\|ZP_01221892.1\| putative alcohol dehydrogenase class III [Photobacterium profundum 3T...	412.0	[0..7]	[379..4]
gi\|238727202, gi... - gi\|77978816\|ref\|ZP_00834240.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia int...	412.0	[0..7]	[378..2]
gi\|46195771, gi\|... - gi\|46195771\|ref\|NP_571924.2\| class III alcohol dehydrogenase, chi subunit [Danio rerio], gi\|45595752...	411.0	[0..3]	[377..2]
gi\|238788842, gi... - gi\|77973854\|ref\|ZP_00829398.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia fre...	411.0	[0..7]	[379..2]
gi\|71145319, gi\|... - gi\|71279579\|ref\|YP_267566.1\| alcohol dehydrogenase, class III [Colwellia psychrerythraea 34H], gi\|71...	411.0	[0..1]	[379..1]

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Predicted Domain #1

Region A:
Residues: [1-379]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNEKPQFIK SKAAVAWGPR QPLKIEEVDV MLPKAGEVLV RIVATGVCHT DAFTLSGDDP  60
   61 EGVFPAILGH EGGGIVEQVG EGVTSVQVGD HVIPLYTPEC GECKFCLSGK TNLCQKIRAT 120
  121 QGKGLMPDGT TRFYKDGQPI FHYMGCSTFS EYTVLPEISL AKVNKTAPLK EICLLGCGVT 180
  181 TGMGAVMNTA KVEAGATVAI FGLGGIGLSA IIGATMAKAS RIIAIDINES KFELARKLGA 240
  241 TDCINPKNFD KPIQEVIVEM TDGGVDYSFE CIGNVNVMRS ALECCHKGWG ESVIIGVAGA 300
  301 GQEISTRPFQ LVTGRVWRGS AFGGVKGRSQ LPKIVEQYLA GEFKLDDFIT HTMGLEQVNE 360
  361 AFDLMHEGKS IRSVIHFDK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	109.0
Match:	1m6hA
Description:	Alcohol dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ethanol binding	4.47659026306883	bayes_pls_golite062009
NAD or NADH binding	4.35058438816264	bayes_pls_golite062009
retinol dehydrogenase activity	4.1750549780559	bayes_pls_golite062009
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
alcohol binding	2.97042200128883	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	2.94416173750168	bayes_pls_golite062009
retinol binding	2.89007863838685	bayes_pls_golite062009
all-trans retinal binding	2.84803957533249	bayes_pls_golite062009
S-(hydroxymethyl)glutathione dehydrogenase activity	2.58673703881996	bayes_pls_golite062009
hydroxymethylfurfural reductase (NADH) activity	2.2999175117758	bayes_pls_golite062009
hydroxymethylfurfural reductase activity	2.2999175117758	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	2.26153457113968	bayes_pls_golite062009
NADPH:quinone reductase activity	2.16668841986245	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	2.03039843216597	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	1.29842732066898	bayes_pls_golite062009
chaperone binding	1.19079350615542	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.01627645289834	bayes_pls_golite062009
binding	0.784517759335365	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.62461633437589	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.527946013169731	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.484089941059577	bayes_pls_golite062009
kinase activity	0.461063813999598	bayes_pls_golite062009
hydroxymethylfurfural reductase (NADPH) activity	0.382131941157781	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.375415252607746	bayes_pls_golite062009
coenzyme binding	0.35922330382799	bayes_pls_golite062009
protein kinase activity	0.339420053437627	bayes_pls_golite062009
nucleic acid binding	0.274019118261823	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.233238483713519	bayes_pls_golite062009
methylenetetrahydrofolate dehydrogenase activity	0.169301675015808	bayes_pls_golite062009
DNA binding	0.164288600669795	bayes_pls_golite062009
methenyltetrahydrofolate cyclohydrolase activity	0.162625185692811	bayes_pls_golite062009
fatty acid synthase activity	0.0962368786590111	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: