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View Structure Prediction Details

Protein: gi|24373377, gi|...
Organism: Shewanella oneidensis MR-1
Length: 397 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24373377, gi|....

Description E-value Query
Range
Subject
Range
gi|28204552, gi|... - gi|28212109|ref|NP_783053.1| methionine gamma-lyase [Clostridium tetani E88], gi|28204552|gb|AAO3699...
344.0 [0..7] [396..4]
gi|21698926 - gi|21698926|dbj|BAC02724.1| L-methionine-alpha-deamino-gamma- mercaptomethane-lyase [Fusobacterium n...
MEGL_FUSNP - L-methionine gamma-lyase OS=Fusobacterium nucleatum subsp. polymorphum GN=mgl PE=1 SV=1
gi|197737499, gi... - gi|254304388|ref|ZP_04971746.1| methionine gamma-lyase [Fusobacterium nucleatum subsp. polymorphum A...
342.0 [0..6] [396..3]
MEGL_FUSNN - L-methionine gamma-lyase OS=Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130...
335.0 [0..7] [396..4]
gi|89210477, gi|... - gi|89210477|ref|ZP_01188866.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [Halothermothrix oren...
334.0 [0..1] [393..1]
gi|78363440, gi|... - gi|78485154|ref|YP_391079.1| O-succinylhomoserine sulfhydrylase [Thiomicrospira crunogena XCL-2], gi...
332.0 [0..1] [397..1]
gi|28883481 - gi|28883481|gb|AAO46884.1| methionine gamma-lyase [Citrobacter freundii]
329.0 [0..1] [396..1]
MEGL_TREDE - L-methionine gamma-lyase OS=Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222) GN=megL...
328.0 [0..1] [397..1]
gi|71143823, gi|... - gi|71278083|ref|YP_268443.1| methionine gamma-lyase [Colwellia psychrerythraea 34H], gi|71143823|gb|...
328.0 [0..1] [396..1]
gi|77164660, gi|... - gi|77164660|ref|YP_343185.1| O-succinylhomoserine sulfhydrylase [Nitrosococcus oceani ATCC 19707], g...
325.0 [0..1] [395..1]

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Predicted Domain #1
Region A:
Residues: [1-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDKSSKMWK AATQAIHAGH EREAFGSLVT PLYQTATFVF DSAQQGGERF AGNEPGYIYT  60
   61 RLGNPTVAEL ERKMAILERA EAAAATASGM GAVSAALLAN LQIGDHLVAS NAVYGCTFAL 120
  121 MTNQFARFGI EVTLVDFSDV ELIERAIKPN TKVIFCETPV NPHLQVFDLS AIAAIAKRHS 180
  181 LTSIVDNTFM TPLLQQPIAL GIDVVVHSAT KYLNGHGDVI AGIVCGSEAQ LHRVKYEILK 240
  241 DIGAVMSPHD AWLILRGLKT LDVRLQRHCE SAQRVAEFLE QHPAVTRVYY PGLKSHSGHR 300
  301 FIGQQMRRAG GVIAFELAAD FTQAMAFVGN LKLFSIAVSL GDAESLIQHP ASMTHSPYSP 360
  361 EARAAAGIGD NLLRISVGLE DCDDIIADLS QALAALV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.69897
Match: 1y4iA
Description: Crystal structure of Citrobacter Freundii L-methionine-lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 2.82824364293374 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 2.82824364293374 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 1.87460342369605 bayes_pls_golite062009
transcription regulator activity 1.67701710033155 bayes_pls_golite062009
DNA binding 1.4774443071095 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
nucleic acid binding 1.39741122443159 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
transcription factor activity 1.15775909410582 bayes_pls_golite062009
binding 1.09053123792737 bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 0.994935084630764 bayes_pls_golite062009
ligase activity 0.827063849687833 bayes_pls_golite062009
carbon-sulfur lyase activity 0.698312655247044 bayes_pls_golite062009
cystathionine beta-lyase activity 0.6849039330512 bayes_pls_golite062009
vitamin binding 0.66463470119531 bayes_pls_golite062009
cystathionine gamma-lyase activity 0.505859361763689 bayes_pls_golite062009
alanine-glyoxylate transaminase activity 0.48682493494502 bayes_pls_golite062009
O-acyltransferase activity 0.452440867878365 bayes_pls_golite062009
cysteine synthase activity 0.417849187928985 bayes_pls_golite062009
structural molecule activity 0.347975812448725 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 0.271623203801431 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity 0.0669652799570574 bayes_pls_golite062009

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