YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24372517, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	664 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24372517, gi|....

Description	E-value	Query Range	Subject Range
gi\|16766377, gi\|... - gi\|16766377\|ref\|NP_461992.1\| transketolase [Salmonella typhimurium LT2], gi\|16421628\|gb\|AAL21951.1\| ... gi\|167990403, gi... - gi\|205331175\|gb\|EDZ17939.1\| transketolase [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- ... lcl\|NC_016856.1_... - [gene=tktA] [protein=transketolase] [protein_id=YP_005239220.1] [location=complement(3255532..325752... gi\|197262122, gi... - gi\|197262122\|ref\|ZP_03162196.1\| transketolase [Salmonella enterica subsp. enterica serovar Saintpaul...	654.0	[0..1]	[663..1]
gi\|29138980, gi\|... - gi\|29143346\|ref\|NP_806688.1\| transketolase [Salmonella enterica subsp. enterica serovar Typhi str. T... gi\|16761859 - gi\|16761859\|ref\|NP_457476.1\| transketolase [Salmonella enterica subsp. enterica serovar Typhi str. C... gi\|16504161, gi\|... - gi\|25286319\|pir\|\|AD0876 transketolase [imported] - Salmonella enterica subsp. enterica serovar Typhi... gi\|213051482 - gi\|213051482\|ref\|ZP_03344360.1\| transketolase [Salmonella enterica subsp. enterica serovar Typhi str... gi\|56129279, gi\|... - gi\|56415022\|ref\|YP_152097.1\| transketolase [Salmonella enterica subsp. enterica serovar Paratyphi A ... gi\|197095428, gi... - gi\|197363951\|ref\|YP_002143588.1\| transketolase [Salmonella enterica subsp. enterica serovar Paratyph... gi\|214002389 - gi\|214002389\|ref\|ZP_03413124.1\| transketolase [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213424121 - gi\|213424121\|ref\|ZP_03357014.1\| transketolase [Salmonella enterica subsp. enterica serovar Typhi str...	653.0	[0..1]	[663..1]
gi\|162138379 - gi\|162138379\|ref\|YP_542302.2\| transketolase [Escherichia coli UTI89] gi\|218559926, gi... - gi\|218559926\|ref\|YP_002392839.1\| transketolase [Escherichia coli S88], gi\|218366695\|emb\|CAR04452.1\| ... gi\|117625164, gi... - gi\|117625164\|ref\|YP_854152.1\| transketolase [Escherichia coli APEC O1], gi\|115514288\|gb\|ABJ02363.1\| ...	652.0	[0..1]	[663..1]
gi\|91073890, gi\|... - gi\|91212316\|ref\|YP_542302.1\| transketolase 1 [Escherichia coli UTI89], gi\|91073890\|gb\|ABE08771.1\| tr... gi\|237706414, gi... - gi\|237706414\|ref\|ZP_04536895.1\| transketolase 1 [Escherichia sp. 3_2_53FAA], gi\|226899454\|gb\|EEH8571...	652.0	[0..1]	[663..11]
gi\|82778297, gi\|... - gi\|82778297\|ref\|YP_404646.1\| transketolase [Shigella dysenteriae Sd197], gi\|81242445\|gb\|ABB63155.1\| ...	652.0	[0..1]	[663..1]
gi\|75178838, gi\|... - gi\|75178838\|ref\|ZP_00698874.1\| COG0021: Transketolase [Shigella boydii BS512], gi\|187733279\|ref\|YP_0...	652.0	[0..1]	[663..1]
gi\|62129221, gi\|... - gi\|62181588\|ref\|YP_218005.1\| transketolase [Salmonella enterica subsp. enterica serovar Choleraesuis...	651.0	[0..1]	[663..1]
gi\|110344676, gi... - gi\|110643084\|ref\|YP_670814.1\| transketolase [Escherichia coli 536], gi\|110344676\|gb\|ABG70913.1\| tran... gi\|75241267, gi\|... - gi\|75241267\|ref\|ZP_00725129.1\| COG0021: Transketolase [Escherichia coli F11], gi\|191171823\|ref\|ZP_03... gi\|227834758, gi... - gi\|227888489\|ref\|ZP_04006294.1\| transketolase [Escherichia coli 83972], gi\|227834758\|gb\|EEJ45224.1\| ... gi\|218691058, gi... - gi\|218691058\|ref\|YP_002399270.1\| transketolase [Escherichia coli ED1a], gi\|218428622\|emb\|CAR09551.2\|...	651.0	[0..1]	[663..1]
gi\|238902057, gi... - gi\|238902057\|ref\|YP_002927853.1\| transketolase 1, thiamin-binding [Escherichia coli BW2952], gi\|2388... gi\|254289605, gi... - gi\|254289605\|ref\|YP_003055353.1\| transketolase 1, thiamin-binding [Escherichia coli BL21(DE3)], gi\|2... gi\|242378462, gi... - gi\|251786189\|ref\|YP_003000493.1\| hypothetical protein B21_02728 [Escherichia coli BL21], gi\|24237846... gi\|157068074, gi... - gi\|75196886\|ref\|ZP_00706956.1\| COG0021: Transketolase [Escherichia coli HS], gi\|157162394\|ref\|YP_001... gi\|209920394, gi... - gi\|209920394\|ref\|YP_002294478.1\| transketolase [Escherichia coli SE11], gi\|209913653\|dbj\|BAG78727.1\|... gi\|194424168, gi... - gi\|83587665\|ref\|ZP_00926292.1\| COG0021: Transketolase [Escherichia coli 101-1], gi\|194436686\|ref\|ZP_... gi\|215266304, gi... - gi\|215488232\|ref\|YP_002330663.1\| transketolase [Escherichia coli O127:H6 str. E2348/69], gi\|21526630... gi\|254162845, gi... - gi\|254162845\|ref\|YP_003045953.1\| transketolase 1, thiamin-binding [Escherichia coli B str. REL606], ... TKT1_ECOLI - Transketolase 1 (EC 2.2.1.1) (TK 1) - Escherichia coli gi\|85675745, gi\|... - gi\|89109712\|ref\|AP_003492.1\| transketolase 1, thiamin-binding [Escherichia coli str. K-12 substr. W3... gi\|169753749, gi... - gi\|170018821\|ref\|YP_001723775.1\| transketolase [Escherichia coli ATCC 8739], gi\|169753749\|gb\|ACA7644... gi\|188493673, gi... - gi\|75515282\|ref\|ZP_00737466.1\| COG0021: Transketolase [Escherichia coli 53638], gi\|188493673\|ref\|ZP_... gi\|170082489, gi... - gi\|170082489\|ref\|YP_001731809.1\| transketolase 1, thiamin-binding [Escherichia coli str. K-12 substr... gi\|218371632, gi... - gi\|218701646\|ref\|YP_002409275.1\| transketolase [Escherichia coli IAI39], gi\|218371632\|emb\|CAR19471.1... gi\|218433545, gi... - gi\|218706448\|ref\|YP_002413967.1\| transketolase [Escherichia coli UMN026], gi\|218433545\|emb\|CAR14448.... EG11427 - transketolase 1, thiamine triphosphate-binding / Transketolase A; binds Zn(II) gi\|218362254, gi... - gi\|218555486\|ref\|YP_002388399.1\| transketolase [Escherichia coli IAI1], gi\|218362254\|emb\|CAQ99875.1\|... gi\|124526162, gi... - gi\|124526162\|ref\|ZP_01698167.1\| transketolase [Escherichia coli B], gi\|124502266\|gb\|EAY49726.1\| tran... gi\|218696532, gi... - gi\|218696532\|ref\|YP_002404199.1\| transketolase [Escherichia coli 55989], gi\|218353264\|emb\|CAU99213.1... EG11427 - transketolase 1, thiamine triphosphate-binding / Transketolase A; binds Zn(II)	651.0	[0..1]	[663..1]
gi\|208727518, gi... - gi\|208807717\|ref\|ZP_03250054.1\| transketolase [Escherichia coli O157:H7 str. EC4206], gi\|208727518\|g... gi\|195936556 - gi\|195936556\|ref\|ZP_03081938.1\| transketolase [Escherichia coli O157:H7 str. EC4024] gi\|208738906, gi... - gi\|208818783\|ref\|ZP_03259103.1\| transketolase [Escherichia coli O157:H7 str. EC4042], gi\|208738906\|g... gi\|208812817, gi... - gi\|208812817\|ref\|ZP_03254146.1\| transketolase [Escherichia coli O157:H7 str. EC4045], gi\|208734094\|g... gi\|217320116, gi... - gi\|217327749\|ref\|ZP_03443832.1\| transketolase [Escherichia coli O157:H7 str. TW14588], gi\|217320116\|... gi\|209161704, gi... - gi\|209400304\|ref\|YP_002272414.1\| transketolase [Escherichia coli O157:H7 str. EC4115], gi\|209161704\|... gi\|13363282, gi\|... - gi\|15833064\|ref\|NP_311837.1\| transketolase [Escherichia coli O157:H7 str. Sakai], gi\|13363282\|dbj\|BA... gi\|254594286, gi... - gi\|254794886\|ref\|YP_003079723.1\| transketolase 1, thiamin-binding [Escherichia coli O157:H7 str. TW1... gi\|188017797, gi... - gi\|188017797\|gb\|EDU55919.1\| transketolase [Escherichia coli O157:H7 str. EC4113], gi\|168747576\|ref\|Z... gi\|157155441, gi... - gi\|75187654\|ref\|ZP_00700921.1\| COG0021: Transketolase [Escherichia coli E24377A], gi\|157155441\|ref\|Y... gi\|189369283, gi... - gi\|189369283\|gb\|EDU87699.1\| transketolase [Escherichia coli O157:H7 str. EC4501], gi\|168760073\|ref\|Z... gi\|189358659, gi... - gi\|189358659\|gb\|EDU77078.1\| transketolase [Escherichia coli O157:H7 str. EC4401], gi\|168753883\|ref\|Z... gi\|81246852, gi\|... - gi\|82545441\|ref\|YP_409388.1\| transketolase [Shigella boydii Sb227], gi\|81246852\|gb\|ABB67560.1\| trans... gi\|187770781, gi... - gi\|187770781\|gb\|EDU34625.1\| transketolase [Escherichia coli O157:H7 str. EC4196], gi\|168773429\|ref\|Z... gi\|189363681, gi... - gi\|189363681\|gb\|EDU82100.1\| transketolase [Escherichia coli O157:H7 str. EC4486], gi\|168766938\|ref\|Z... gi\|75239493, gi\|... - gi\|75239493\|ref\|ZP_00723464.1\| COG0021: Transketolase [Escherichia coli E110019], gi\|193067298\|ref\|Z... gi\|189374031, gi... - gi\|189374031\|gb\|EDU92447.1\| transketolase [Escherichia coli O157:H7 str. EC869], gi\|168785789\|ref\|ZP... gi\|74313492, gi\|... - gi\|74313492\|ref\|YP_311911.1\| transketolase [Shigella sonnei Ss046], gi\|73856969\|gb\|AAZ89676.1\| trans... gi\|168781790, gi... - gi\|189000631\|gb\|EDU69617.1\| transketolase [Escherichia coli O157:H7 str. EC4076], gi\|168781790\|ref\|Z... gi\|25286310, gi\|... - pir\|\|B91105 transketolase 1 isozyme [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0... gi\|13363282, gi\|... - gi\|15833064\|ref\|NP_311837.1\| transketolase [Escherichia coli O157:H7], gi\|13363282\|dbj\|BAB37233.1\| t...	650.0	[0..1]	[663..1]

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Predicted Domain #1

Region A:
Residues: [1-664]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRKVLANA IRALSMDAVQ KANSGHPGAP MGMADIAEVL WNDFLKHNPN NPKWVDRDRF  60
   61 ILSNGHGSML IYSLLHLTGY DLPMDELKQF RQLHSKTPGH PEYGYTPGVE TTTGPLGAGI 120
  121 SNAVGMAIAE KTLAAQFNRE GHEIVDHYTY CFLGDGCLME GISHEACSLA GTLGLGKLIA 180
  181 FWDDNGISID GHVEGWFTDD TPKRFESYGW HVIANVDGHD SDAIRAAIEA AKAVTDKPTM 240
  241 ICCKTIIGFG SPNKSGSHDC HGAPLGDAEI AAAREFLGWP HAPFEIPADV YAGWDAKDAG 300
  301 AAREAAWNDK FAAYAAAYPE LAAEYERRVL KGELPADFEA KAQAFIQECQ AKGEGIASRK 360
  361 ASQNAIAAFG AILPELLGGS ADLAGSNLTL WAGSKGIQDD PAGNYVYYGV REFGMSGIMN 420
  421 GVSLHGGFIN YGATFMMFME YARNAVRMSA LMGIQNIFVY THDSIGQGED GQLTNPFEQL 480
  481 ANLRMTPNMA VWRPCDAAET AVAWKAAIER RHAPTSLIFS RQNLKAQART AEQLANVAKG 540
  541 AYVLQDCAAT PEYILIATGS EVQLAMEAAA TLTEQGKQVR VVSMPSNTEF DKQDAAYKES 600
  601 VLPKAVTKRI AIEAAHTDFW YKYVGFEGTV VGMTTFGESA PGNVLLKHFG FTVENVLNAA 660
  661 KSLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1qgdA
Description:	Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transketolase activity	6.17852985073866	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	2.93250853993668	bayes_pls_golite062009
pyruvate dehydrogenase activity	2.81702263447118	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	2.6977837113283	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.21959520697519	bayes_pls_golite062009
catalytic activity	0.545407789079971	bayes_pls_golite062009
binding	0.508291294830325	bayes_pls_golite062009
acetolactate synthase activity	0.159086519260601	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: