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View Structure Prediction Details

Protein: FTHS_SHEON
Organism: Shewanella oneidensis MR-1
Length: 570 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTHS_SHEON.

Description E-value Query
Range		 Subject
Range
FTHS_MOOTA - Formate--tetrahydrofolate ligase OS=Moorella thermoacetica (strain ATCC 39073) GN=fhs PE=1 SV=1
 966.0 [0..1] [569..4]
FTHS_MOOTH - Formate--tetrahydrofolate ligase OS=Moorella thermoacetica GN=fhs PE=1 SV=1
 959.0 [0..1] [569..4]
FTHS_ALKOO - Formate--tetrahydrofolate ligase OS=Alkaliphilus oremlandii (strain OhILAs) GN=fhs PE=3 SV=1
 952.0 [0..1] [569..1]
gi|219536478, gi... - gi|68208618|ref|ZP_00560721.1| Formate--tetrahydrofolate ligase [Desulfitobacterium hafniense DCB-2]...
FTHS1_DESHY - Formate--tetrahydrofolate ligase 1 OS=Desulfitobacterium hafniense (strain Y51) GN=fhs1 PE=3 SV=1
 938.0 [0..1] [569..1]
FTHS_CLOTH - Formate--tetrahydrofolate ligase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 10...
 937.0 [0..1] [569..1]
gi|242231726, gi... - gi|242256735|ref|ZP_04801620.1| Formate--tetrahydrofolate ligase [Thermoanaerobacter sp. X513], gi|2...
FTHS_THEPX - Formate--tetrahydrofolate ligase OS=Thermoanaerobacter sp. (strain X514) GN=fhs PE=3 SV=1
 934.0 [0..1] [569..1]
gi|89272471 - gi|89272471|emb|CAJ82471.1| methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltet...
 930.0 [0..1] [569..315]
FTHS_SINMW - Formate--tetrahydrofolate ligase OS=Sinorhizobium medicae (strain WSM419) GN=fhs PE=3 SV=1
 930.0 [0..1] [569..12]

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Predicted Domain #1
Region A:
Residues: [1-570] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTDMEISRR AHLKDIAQLG AEFGLLPEEM QLFGNTKAKV DLQVQQRLAG QPKGKLIIVT  60
   61 AVTPTPHGEG KTVTTIGLTQ SLKALGNKVC ACIRQPSMGP VFGVKGGAAG GGYAQVVPMQ 120
  121 ELNLHLTGDI HAVSSAHNLG AAAIASRLYH EMRLGKAEFE RQSGLSYLDI DPKGIRWHRV 180
  181 VDHNDRCLRE IEVGLGENNG PAYTSGFDIT AASELMAILA LSRNLTDMRV RIGKLVLALN 240
  241 RQGEAVSADE LGVAGAMTAI MADAVKPTLM QTLNGAPCLI HAGPFANIAH GNSSVIADDI 300
  301 ALKLADFVVT EGGFGSDMGF EKFCNIKARQ SGLIPSAAVL VTTLKALKAN SGLASDTDIN 360
  361 APDQARLEAG FANLNWHINN VVQYGLPVVV AINRFASDTD AELNWLMEAV RGTAAFGCEL 420
  421 SEAFSQGEDG AMALAQTVIR ACEQPSEFRL LYPDNMELEA KLSTLAELGY GAAGINLSAV 480
  481 AKQQLQELSA LGYAHLPVCM AKTPLSISHD PQLKGVPQGF IVPVRELVLN AGAGFITALV 540
  541 GNVMTMPGLG LTPGYLKIDI DVDGEIIGLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1fp7A
Description: Formyltetrahydrofolate synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity 0.12351419478929 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle