YRC Public Data Repository - Protein Structure Prediction

Protein:	AROE_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	287 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AROE_SHEON.

Description	E-value	Query Range	Subject Range
gi\|167037479, gi... - gi\|76797197\|ref\|ZP_00779533.1\| Quinate/Shikimate 5-dehydrogenase [Thermoanaerobacter ethanolicus ATC...	246.0	[0..1]	[281..1]
AROE_ALKMQ - Shikimate dehydrogenase (NADP(+)) OS=Alkaliphilus metalliredigens (strain QYMF) GN=aroE PE=3 SV=1	245.0	[0..3]	[282..4]
gi\|114845254, gi... - gi\|167040141\|ref\|YP_001663126.1\| shikimate 5-dehydrogenase [Thermoanaerobacter sp. X514], gi\|1668543...	242.0	[0..1]	[281..1]
AROE_THETN - Shikimate dehydrogenase OS=Thermoanaerobacter tengcongensis GN=aroE PE=3 SV=1 AROE_CALS4 - Shikimate dehydrogenase (NADP(+)) OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM ... gi\|214034934, gi... - gi\|254479120\|ref\|ZP_05092471.1\| shikimate 5-dehydrogenase [Carboxydibrachium pacificum DSM 12653], g...	242.0	[0..3]	[283..2]
AROE_SHESM - Shikimate dehydrogenase (NADP(+)) OS=Shewanella sp. (strain MR-4) GN=aroE PE=3 SV=1	236.0	[0..2]	[286..6]
gi\|227883413, gi... - gi\|227883413\|ref\|ZP_04001218.1\| shikimate 5-dehydrogenase [Escherichia coli 83972], gi\|227839557\|gb\|... AROE_ECOL6 - Shikimate dehydrogenase OS=Escherichia coli O6 GN=aroE PE=3 SV=1 AROE_ECOL6 - Shikimate dehydrogenase (NADP(+)) OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=...	235.0	[0..8]	[283..1]
AROE_SHESR - Shikimate dehydrogenase (NADP(+)) OS=Shewanella sp. (strain MR-7) GN=aroE PE=3 SV=1	234.0	[0..2]	[286..6]
AROE_SHEFN - Shikimate dehydrogenase (NADP(+)) OS=Shewanella frigidimarina (strain NCIMB 400) GN=aroE PE=3 SV=1	233.0	[0..7]	[286..1]
AROE_SHESW - Shikimate dehydrogenase (NADP(+)) OS=Shewanella sp. (strain W3-18-1) GN=aroE PE=3 SV=1 AROE_SHEPC - Shikimate dehydrogenase (NADP(+)) OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=aroE P...	233.0	[0..7]	[286..1]
AROE_METKA - Shikimate dehydrogenase OS=Methanopyrus kandleri GN=aroE PE=3 SV=1 AROE_METKA - Shikimate dehydrogenase (NADP(+)) OS=Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC...	233.0	[0..4]	[284..7]

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Predicted Domain #1

Region A:
Residues: [1-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTSPIVDR YAVFGHPIGH SKSPFIHGQF AALTQESLTY EAILAPIDGF EASLKSFFSS  60
   61 GGKGANVTVP FKEQAFALCD SLSAEAALAG AVNTLSLLAD GSIRGDNTDG LGLVADLISH 120
  121 LGSLQHKRVL LVGAGGAARG CILPLLNAGV GQLVITNRTQ TKAKDLVDIF SQLEEGIYKD 180
  181 KLQALSMSEL TGEFELVINS TSASLAGELP PLPQSIIGST TVCYDMMYGA MPTAFNQWAL 240
  241 QQGAAKVIDG LGMLVGQAAK SFALWRTVEP DTAVVLKLLR EKLQLDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.221849
Match:	1nytA
Description:	Shikimate 5-dehydrogenase AroE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
shikimate 5-dehydrogenase activity	3.40568087442781	bayes_pls_golite062009
malate dehydrogenase activity	3.18316725684556	bayes_pls_golite062009
malic enzyme activity	2.5718745582089	bayes_pls_golite062009
oxidoreductase activity	2.15129810845685	bayes_pls_golite062009
catalytic activity	2.0643953589843	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.43144163429682	bayes_pls_golite062009
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	0.858327241653065	bayes_pls_golite062009
fatty acid synthase activity	0.714637370305282	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.39426299750207	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.192594057004213	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: