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View Structure Prediction Details

Protein: PGTB2_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 325 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGTB2_YEAST.

Description E-value Query
Range		 Subject
Range
PGTB2_YEAST - Geranylgeranyl transferase type-2 subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
gi|190408099 - gi|190408099|gb|EDV11364.1| geranylgeranyltransferase type II beta subunit [Saccharomyces cerevisiae...
gi|207340213 - gi|207340213|gb|EDZ68633.1| YPR176Cp-like protein [Saccharomyces cerevisiae AWRI1631]
BET2 - Beta subunit of Type II geranylgeranyltransferase required for vesicular transport between the endop...
 0.0 [1..325] [1..325]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 2.0E-97 [1..322] [1..322]
gi|208967224 - gi|208967224|dbj|BAG73626.1| Rab geranylgeranyltransferase beta subunit [synthetic construct]
ENSPTRT00000001654 - null
RABGGTB - Rab geranylgeranyltransferase, beta subunit
gi|109008511 - gi|109008511|ref|XP_001101556.1| PREDICTED: similar to Rab geranylgeranyltransferase, beta subunit [...
 3.0E-96 [6..323] [17..327]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 8.0E-96 [6..323] [17..327]
gi|385477 - gi|385477|gb|AAB27019.1| Rab geranylgeranyl transferase component B beta subunit; Rab GG transferase...
PGTB2_RAT - Geranylgeranyl transferase type-2 subunit beta OS=Rattus norvegicus GN=Rabggtb PE=1 SV=1
 1.0E-95 [6..323] [17..327]
PGTB_MOUSE, PGTB... - Geranylgeranyl transferase type-2 subunit beta - Mus musculus (Mouse), Geranylgeranyl transferase ty...
 2.0E-92 [6..323] [25..335]
betaggt-II-PA - The gene Ã?ŽÃ?² subunit of type II geranylgeranyl transferase is referred to in FlyBase by the...
gi|220956328, gi... - gi|220956328|gb|ACL90707.1| betaggt-II-PA [synthetic construct], gi|220946648|gb|ACL85867.1| betaggt...
 7.0E-91 [5..323] [27..341]

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Predicted Domain #1
Region A:
Residues: [1-15] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSLTLLKE KHIRY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [163-325] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVLKCYNFDG GFGLCPNAES HAAQAFTCLG ALAIANKLDM LSDDQLEEIG WWLCERQLPE  60
   61 GGLNGRPSKL PDVCYSWWVL SSLAIIGRLD WINYEKLTEF ILKCQDEKKG GISDRPENEV 120
  121 DVFHTVFGVA GLSLMGYDNL VPIDPIYCMP KSVTSKFKKY PYK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1053.68867
Match: 1dceB_
Description: Rab geranylgeranyltransferase, beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein prenyltransferase activity 13.7736019666673 bayes_pls_golite062009
protein geranylgeranyltransferase activity 12.9757276506747 bayes_pls_golite062009
Rab geranylgeranyltransferase activity 12.8088011327065 bayes_pls_golite062009
prenyltransferase activity 11.6786310564018 bayes_pls_golite062009
CAAX-protein geranylgeranyltransferase activity 10.5569796788906 bayes_pls_golite062009
protein farnesyltransferase activity 4.15546866363415 bayes_pls_golite062009
binding 1.68564752993879 bayes_pls_golite062009
protein binding 1.45455287827127 bayes_pls_golite062009
transferase activity 1.0950430724883 bayes_pls_golite062009
catalytic activity 0.497699107100544 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [16-162] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IESLDTKKHN FEYWLTEHLR LNGIYWGLTA LCVLDSPETF VKEEVISFVL SCWDDKYGAF  60
   61 APFPRHDAHL LTTLSAVQIL ATYDALDVLG KDRKVRLISF IRGNQLEDGS FQGDRFGEVD 120
  121 TRFVYTALSA LSILGELTSE VVDPAVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1053.68867
Match: 1dceB_
Description: Rab geranylgeranyltransferase, beta subunit
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle