YRC Public Data Repository - Protein Structure Prediction

Protein:	LEO1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	464 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LEO1_YEAST.

Description	E-value	Query Range	Subject Range
gi\|190407451 - gi\|190407451\|gb\|EDV10718.1\| protein LEO1 [Saccharomyces cerevisiae RM11-1a] LEO1 - Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone me... gi\|151945744 - gi\|151945744\|gb\|EDN63985.1\| conserved protein [Saccharomyces cerevisiae YJM789] LEO1_YEAST - RNA polymerase-associated protein LEO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=L...	0.0	[1..464]	[1..464]
gi\|1658503 - gi\|1658503\|gb\|AAB18341.1\| Atu [Drosophila melanogaster]	0.0	[4..450]	[245..673]
CE05166 - Yeast LEO1 protein like status:Confirmed UniProt:Q17431 protein_id:CAA97406.1	2.0E-84	[2..420]	[24..410]
VIP4_ARATH - Protein LEO1 homolog OS=Arabidopsis thaliana GN=VIP4 PE=1 SV=1	8.0E-79	[2..397]	[99..489]
LEO1 - Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) gi\|114657092 - gi\|114657092\|ref\|XP_510408.2\| PREDICTED: Leo1, Paf1/RNA polymerase II complex component, homolog iso...	8.0E-76	[8..454]	[189..656]
SPBC13E7.08c - RNA polymerase II associated Paf1 complex YOH8_SCHPO - Uncharacterized protein C13E7.08c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC13E7...	5.0E-67	[69..419]	[2..338]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSESPQDQP QKEQISNNVG VTTNSTSNEE TSRSQDDNVK EVNGNDDTKE EEQEEDAELD  60
   61 DLFGDDNDDD DDDDVKKSET EKSDSDSDED DEGENINHRS RHRESLGLDD DEAEEQAMYT 120
  121 RKFYGEDANN FSDQDETTHT FKEENVELVR HIIPSKANVN ETASHNEIFY ARIPNFLTID 180
  181 P

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [182-464]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPFDPPSFEA KVNERASNSA SREDQLDDRL IDENTVRWRY SRDKDQHVFK ESNTQIVQWS  60
   61 DGTYSLKVGE ECTDILVNDT SNTFLTVSHD QQELIQCYEG GEIKKTLMFI PTSTNSKIHQ 120
  121 KLSKAVIRRN QRQSKGPGTY IVSMDPEVEK KELERKQSQI LRDRRRRQLK EKEKQESPDA 180
  181 AFETGFRKQN SPTTYGASRR NEYEEDDFLV DDDEEEEAAF DDEEDDNEEE EEEEDADEEN 240
  241 ASRLRNLKRE GAAMYREEEE EEKDRSETKR RRVAVIEDDE DED

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [166-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEIFYARIPN FLTIDPIPFD PPSFEAKVNE RASNSASRED QLDDRLIDEN TVRWRYSRDK  60
   61 DQHVFKESNT QIVQW

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [241-464]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDGTYSLKVG EECTDILVND TSNTFLTVSH DQQELIQCYE GGEIKKTLMF IPTSTNSKIH  60
   61 QKLSKAVIRR NQRQSKGPGT YIVSMDPEVE KKELERKQSQ ILRDRRRRQL KEKEKQESPD 120
  121 AAFETGFRKQ NSPTTYGASR RNEYEEDDFL VDDDEEEEAA FDDEEDDNEE EEEEEDADEE 180
  181 NASRLRNLKR EGAAMYREEE EEEKDRSETK RRRVAVIEDD EDED

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits