| Protein: | HMS2_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 358 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HMS2_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [1..358] | [1..358] |
|
|
4.0E-67 | [6..229] | [33..251] |
|
|
8.0E-63 | [3..227] | [8..227] |
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1.0E-62 | [3..227] | [8..227] |
|
|
1.0E-61 | [2..239] | [3..221] |
|
|
1.0E-61 | [6..229] | [35..253] |
|
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2.0E-61 | [6..243] | [14..250] |
|
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2.0E-61 | [6..243] | [14..250] |
|
|
3.0E-61 | [3..227] | [8..227] |
|
Region A: Residues: [1-113] |
1 11 21 31 41 51
| | | | | |
1 MDATSRMEQP DVFVSKLYHL LQGNAYSNII QWSTDGSKLV IWNPDQFTKV ILERFFGIHT 60
61 FAAFVKQLSK YNFQKAGRPD CVEFSNIHFQ KDNINSLSLV KAHQSAATPN VAA
|
| Detection Method: |  |
| Confidence: | 86.124002 |
| Match: | 3htsB_ |
| Description: | Heat-shock transcription factor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 3.50995556050336 | bayes_pls_golite062009 |
| binding | 3.33026160538031 | bayes_pls_golite062009 |
| DNA binding | 3.22637331076146 | bayes_pls_golite062009 |
| nucleic acid binding | 3.05427098674 | bayes_pls_golite062009 |
| transcription factor activity | 2.60537570879007 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.32971938164691 | bayes_pls_golite062009 |
| transcription activator activity | 1.09351769815632 | bayes_pls_golite062009 |
| transcription repressor activity | 0.97608021324937 | bayes_pls_golite062009 |
| protein binding | 0.653872239015235 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.29742933266479 | bayes_pls_golite062009 |
|
Region A: Residues: [114-253] |
1 11 21 31 41 51
| | | | | |
1 VNNMNKQCTF HWDPFKVNSI LSKAIGKPSF EKLVKNVDRL QGNLDELKST NADSLRIIRE 60
61 INASLQTISY HQFHAYQTAN FLQENFEAIK KVVCPDSCLQ HQQRQPKRPK RYSLLLLIPN 120
121 ASELSETPLM RFAGVFEFMN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.261 | 0.295 | pseudohyphal growth | a.1.1 | Globin-like |
| View | Download | 0.271 | 0.174 | pseudohyphal growth | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.268 | 0.064 | pseudohyphal growth | a.77.1 | DEATH domain |
| View | Download | 0.236 | 0.038 | pseudohyphal growth | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.271 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.268 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.261 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.236 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.234 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.234 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.231 | N/A | N/A | a.1.1 | Globin-like |
|
Region A: Residues: [254-358] |
1 11 21 31 41 51
| | | | | |
1 CSLDTATQWH PQLHPEAYDL LFVTVSPNMQ QEHLIYFKRL RNLLPSFPVI AIINRPVSPQ 60
61 DTSIAPSNYS RYYFHHFLQL GFSDILVSPF TPTQLITLLS KHLRT
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.899 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.899 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.889 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.878 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.874 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.860 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.860 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.830 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.745 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.479 | 0.840 | pseudohyphal growth | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.438 | 0.840 | pseudohyphal growth | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.417 | 0.840 | pseudohyphal growth | c.23.1 | CheY-like |
| View | Download | 0.404 | 0.840 | pseudohyphal growth | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.400 | 0.840 | pseudohyphal growth | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.391 | 0.840 | pseudohyphal growth | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.377 | 0.840 | pseudohyphal growth | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.351 | 0.840 | pseudohyphal growth | c.10.1 | RNI-like |
| View | Download | 0.342 | 0.840 | pseudohyphal growth | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.333 | 0.840 | pseudohyphal growth | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.318 | 0.840 | pseudohyphal growth | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.308 | 0.840 | pseudohyphal growth | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.306 | 0.840 | pseudohyphal growth | c.10.1 | RNI-like |
| View | Download | 0.303 | 0.840 | pseudohyphal growth | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.298 | 0.840 | pseudohyphal growth | c.23.6 | Cobalamin (vitamin B12)-binding domain |
| View | Download | 0.297 | 0.840 | pseudohyphal growth | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.274 | 0.840 | pseudohyphal growth | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.252 | 0.840 | pseudohyphal growth | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.250 | 0.840 | pseudohyphal growth | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.241 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.231 | 0.840 | pseudohyphal growth | c.26.2 | Adenine nucleotide alpha hydrolases-like |
| View | Download | 0.230 | 0.840 | pseudohyphal growth | g.45.1 | Pyk2-associated protein beta ARF-GAP domain |
| View | Download | 0.221 | 0.840 | pseudohyphal growth | c.23.4 | Succinyl-CoA synthetase domains |
| View | Download | 0.219 | 0.840 | pseudohyphal growth | c.15.1 | BRCT domain |
| View | Download | 0.217 | 0.840 | pseudohyphal growth | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.215 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.215 | 0.840 | pseudohyphal growth | c.114.1 | YchN-like |
| View | Download | 0.213 | 0.840 | pseudohyphal growth | d.68.4 | YhbY-like |
| View | Download | 0.213 | 0.840 | pseudohyphal growth | d.74.4 | Prokaryotic AspRS, insert domain |
| View | Download | 0.213 | 0.840 | pseudohyphal growth | c.47.1 | Thioredoxin-like |
| View | Download | 0.213 | 0.840 | pseudohyphal growth | c.114.1 | YchN-like |
| View | Download | 0.209 | 0.840 | pseudohyphal growth | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.208 | 0.840 | pseudohyphal growth | c.57.1 | Molybdenum cofactor biosynthesis proteins |
| View | Download | 0.203 | 0.840 | pseudohyphal growth | c.23.1 | CheY-like |
